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|Insulin Detemir Cartridges

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Insulin Detemir Cartridges

Generic Name: Insulin Detemir Cartridges and Prefilled Syringes (IN-su-lin DE-te-meer)
Brand Name: Levemir

Insulin Detemir Cartridges is used for:

Treating diabetes mellitus.

Insulin Detemir Cartridges is a hormone that is produced by the pancreas and is necessary for the body"s correct use of food, especially sugar. Diabetes occurs when the pancreas does not make enough insulin to meet the body"s needs. Insulin helps to keep blood glucose at a nearly normal level.

Do NOT use Insulin Detemir Cartridges if:

you are allergic to any ingredient in Insulin Detemir Cartridges
you are having an episode of low blood sugar

Contact your doctor or health care provider right away if any of these apply to you.

Before using Insulin Detemir Cartridges:

Some medical conditions may interact with Insulin Detemir Cartridges. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you drink alcoholic beverages
if you have kidney or liver problems, diabetic ketoacidosis, or nerve problems
if you have high blood sodium levels or you are on a low sodium diet

Some MEDICINES MAY INTERACT with Insulin Detemir Cartridges. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), clonidine, or lithium because the risk of high or low blood sugar may be increased
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), disopyramide, fenfluramine, fibrates (eg, clofibrate, gemfibrozil), fluoxetine, monoamine oxidase (MAO) inhibitors (eg, phenelzine), oral medicines for diabetes (eg, glipizide, metformin, nateglinide), pentamidine, propoxyphene, salicylates (eg, aspirin), somatostatin analogs (eg, octreotide), or sulfonamide antibiotics (eg, sulfamethoxazole) because the risk of low blood sugar may be increased
Corticosteroids (eg, propranolol), danazol, diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), isoniazid, phenothiazines (eg, chlorpromazine), progesterones (eg, medroxyprogesterone), somatropin, sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid hormones (eg, levothyroxine) because they may decrease Insulin Detemir Cartridges"s effectiveness, resulting in high blood sugar
Beta-blockers (eg, propranolol), clonidine, guanethidine, or reserpine because they may decrease or hide the signs and symptoms of low blood sugar if it occurs

This may not be a complete list of all interactions that may occur. Ask your health care provider if Insulin Detemir Cartridges may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Insulin Detemir Cartridges:

Use Insulin Detemir Cartridges as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An additional patient leaflet is available with Insulin Detemir Cartridges. Talk to your pharmacist if you have questions about this information.
Insulin Detemir Cartridges may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
If you are using Insulin Detemir Cartridges at home, carefully follow the injection procedures taught to you by your health care provider. Inject deep under the skin, NOT into a vein or muscle.
Injection sites within an injection area (eg, abdomen, thigh, upper arm) must be rotated from one injection to the next.
Insulin Detemir Cartridges is a clear, colorless solution. If the medicine contains particles or is discolored, or if the container is cracked or damaged in any way, do not use it.
Be sure you have purchased the correct insulin. Insulin comes in a variety of containers, including vials, cartridges, and pens. Make sure that you understand how to properly measure and prepare your dose. If you have any questions about measuring and preparing your dose, contact your doctor or pharmacist for information.
Do not mix this insulin with any other type of insulin or medicine in the same syringe.
Do not use Insulin Detemir Cartridges in an insulin infusion pump.
Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
It is very important to follow your insulin regimen exactly. Do NOT miss any doses. Ask your doctor for specific instructions to follow in case you ever miss a dose of insulin.

Ask your health care provider any questions you may have about how to use Insulin Detemir Cartridges.

Important safety information:

Insulin Detemir Cartridges may cause drowsiness, dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Insulin Detemir Cartridges. Using Insulin Detemir Cartridges alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
Do not drink alcohol without discussing it with your doctor. Drinking alcohol may increase your risk of developing high or low blood sugar.
Illness, especially with nausea and vomiting, emotional problems, stress, or changes in diet or activity level may cause your insulin requirements to change. Even if you are not eating, you still require insulin. You and your doctor should establish a sick day plan to use in case of illness. When you are sick, test your blood/urine frequently and call your doctor as instructed.
If you will be traveling across time zones, ask your doctor about adjustments to your insulin schedule.
Proper diet, regular exercise, and regular testing of blood sugar are important for best results when using Insulin Detemir Cartridges. Follow your doctor"s instructions carefully. If your blood sugar level is often higher than it should be and you are taking Insulin Detemir Cartridges according to the directions, check with your doctor.
Carry an identification card at all times that says you have diabetes.
Do not exceed the recommended dose, use Insulin Detemir Cartridges more often than prescribed, or change the type or dose of insulin you are taking without first checking with your doctor.
An insulin reaction resulting from low blood sugar levels (hypoglycemia) may occur if you take too much insulin, skip a meal, or exercise too much. Signs of hypoglycemia include increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, or fainting. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you do not have a reliable source of glucose available, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. Tell your doctor immediately about the reaction.
Developing a fever or infection, eating significantly more than usual, or missing your dose of insulin may cause high blood sugar (hyperglycemia). Symptoms of hyperglycemia include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor immediately. If not treated, loss of consciousness, coma, or death may occur.
Lab tests, such as fasting blood glucose levels or glycosylated hemoglobin levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
Use Insulin Detemir Cartridges with caution in the ELDERLY because they may be more sensitive to its effects, especially low blood sugar.
Use Insulin Detemir Cartridges with extreme caution in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Insulin Detemir Cartridges during pregnancy. It is unknown if Insulin Detemir Cartridges is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the benefits and risks to your baby.

Possible side effects of Insulin Detemir Cartridges:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Depression in the skin; enlargement or thickening of the skin; redness, swelling, mild pain, or itching at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chills; dizziness; drowsiness; fainting; fast heartbeat; fast, shallow breathing; headache; hoarseness; increased hunger, thirst, or urination; loss of consciousness; nervousness; seizures; slurred speech; stomach pain; sweating; sweet or fruity breath; swelling of arms or legs; tremor; weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm) or emergency room immediately. Symptoms may include chills; dizziness; drowsiness; fainting; headache; increased heartbeat; increased hunger; loss of consciousness; nervousness; seizures; shakiness; sweating; tremor; vision changes; weakness.

Proper storage of Insulin Detemir Cartridges:

Store new (unopened) cartridges and prefilled syringes in a refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze Insulin Detemir Cartridges. Store used (open) cartridges and prefilled syringes at room temperature, below 86 degrees F (30 degrees C). Do NOT store used (open) cartridges or prefilled syringes in the refrigerator. Store away from heat and light. If Insulin Detemir Cartridges has been frozen or overheated, throw it away.

Do not leave Insulin Detemir Cartridges in a car on a warm or sunny day. Do not use Insulin Detemir Cartridges after the expiration date stamped on the label. Throw away used cartridges or prefilled syringes 28 days after the first use, even if they still contain medicine. Keep Insulin Detemir Cartridges, as well as syringes and needles, out of the reach of children and away from pets.

General information:

If you have any questions about Insulin Detemir Cartridges, please talk with your doctor, pharmacist, or other health care provider.
Insulin Detemir Cartridges is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Insulin Detemir Cartridges. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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