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|Herceptin |
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In Canada—
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DescriptionTrastuzumab (tras-TOO-ze-mab) is a monoclonal antibody. It is used to treat breast cancer that has spread to other parts of the body. Trastuzumab may prevent the growth of some breast tumors that produce extra amounts of a certain substance known as the HER2 protein. Trastuzumab should be used only in certain patients whose breast tumors have been shown to produce extra amounts of this protein. Trastuzumab is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form:
Before Using This MedicineIn deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For trastuzumab, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to trastuzumab, to mouse proteins, or to benzyl alcohol. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy—Trastuzumab has not been studied in pregnant women. However, this medicine was found to cross the placenta in monkeys but did not cause harmful effects in the fetus. Before receiving this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant. Breast-feeding—It is not known whether trastuzumab passes into the breast milk. However, breast-feeding is not recommended while you are receiving this medicine and for a while after you stop receiving it. Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of trastuzumab in children with use in other age groups. Older adults—There is no specific information comparing the use of trastuzumab in the elderly with use in other age groups. However, certain heart problems may be more likely to occur in the elderly, who may be more sensitive to the effects of trastuzumab. Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Other medical problems—The presence of other medical problems may affect the use of trastuzumab. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This MedicineDosing—The dose of trastuzumab will be different for different patients. The dose that is used may depend on a number of things, including your size. Trastuzumab usually is given by a doctor or nurse in the hospital or outpatient clinic. If you have any questions about the proper dose of trastuzumab, ask your doctor. Precautions While Using This MedicineIt is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for any unwanted effects. Contact your doctor immediately if you experience any chest pain, increased coughing, troubled breathing, sudden difficulty breathing at night, or abnormal swelling of your ankles or legs. These could be symptoms of serious heart problems. Side Effects of This MedicineAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur during or after the administration of trastuzumab : More common Dizziness; fever or chills; headache; nausea or vomiting; shortness of breath; skin rash; weakness Rare Tightness in chest; troubled breathing; wheezing Check with your doctor as soon as possible if any of the following side effects occur: Less common Fast or irregular heartbeat; increased cough; swelling of feet or lower legs Rare Blue lips and fingernails; blurred vision; chest pain; confusion; cough or hoarseness, accompanied by fever or chills; faintness or light-headedness when getting up from a lying or sitting position; increased sweating; itching; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, feet, or sex organs; lower back or side pain, accompanied by fever or chills; painful or difficult urination, accompanied by fever or chills; pale skin; redness of skin; unusual tiredness or weakness Incidence not known Black, tarry stools; cough; shortness of breath; sore throat; sores, ulcers, or white spots in mouth; unusual bleeding or bruising Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Diarrhea; pain Less common Loss of appetite; numbness or tingling of hands or feet; runny nose; trouble in sleeping Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Revised: 09/19/2005 The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Where can I get more information about Herceptin ? 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