Glyset

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Glyset


Generic Name: Miglitol (MIG-li-tol)
Brand Name: Glyset

Glyset is used for:

Treating type 2 diabetes in adults whose diabetes cannot be managed with diet alone. Glyset may be used alone, in combination with other oral diabetes medicines, or with insulin.

Acarbose is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose. This decreases blood sugar levels following a meal.

Do NOT use Glyset if:

  • you are allergic to any ingredient in Glyset
  • you have blockage of the stomach or intestine or are at risk for these problems
  • you have long-term (chronic) bowel inflammation, colon ulcers, or stomach or intestine problems that interfere with digestion or nutrient absorption
  • you have diabetic ketoacidosis (high ketone levels) or moderate to severe kidney problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Glyset :

Some medical conditions may interact with Glyset . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach or intestinal problems, liver problems, or kidney problems

Some MEDICINES MAY INTERACT with Glyset . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Insulin or sulfonylureas (eg, glyburide) because side effects may be increased by Glyset
  • Digoxin, propranolol, or ranitidine because their effectiveness may be decreased by Glyset

This may not be a complete list of all interactions that may occur. Ask your health care provider if Glyset may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Glyset :

Use Glyset as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Glyset with the first bite of each main meal, unless directed otherwise by your doctor.
  • If you are also taking charcoal or digestive enzyme preparations with Glyset , space them at least 2 to 4 hours apart for maximum effectiveness.
  • Carefully follow the diet and exercise program given to you by your health care provider.
  • Temporary insulin therapy may be necessary during stressful periods (such as fever, trauma, infection, or surgery).
  • If you miss a dose of Glyset , skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Glyset .

Important safety information:

  • Notify your dentist or doctor that you are taking Glyset before you have any dental work or surgery.
  • Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider.
  • Glyset , used with other diabetes medicines, may cause a loss of blood sugar control. Your health care provider may need to change the amount of medicine that you are taking. Because Glyset prevents the breakdown of table (cane) sugar, be sure to use glucose (dextrose), not sugar or fruits, to treat symptoms of low blood sugar (tiredness, excessive hunger and sweating, numbness in arms or legs). Contact your health care provider if these symptoms occur.
  • LAB TESTS, including blood glucose and glycosylated hemoglobin levels, may be performed to monitor your progress and to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Glyset with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Glyset , discuss with your doctor the benefits and risks of using Glyset during pregnancy. Glyset is excreted in breast milk. Do not breast feed while taking Glyset .

Possible side effects of Glyset :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloating; diarrhea; gas; soft stools; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe stomach pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include severe or persistent diarrhea, gas, or stomach pain or discomfort.

Proper storage of Glyset :

Store Glyset at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Glyset out of the reach of children and away from pets.

General information:

  • If you have any questions about Glyset , please talk with your doctor, pharmacist, or other health care provider.
  • Glyset is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Glyset . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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