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|Glyburide Micronized Glyburide Micronized

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Glyburide Micronized

Generic Name: Glyburide Micronized Tablets (GLYE-byoor-ide)
Brand Name: Glynase Pres Tab

Glyburide Micronized is used for:

Treating patients with type 2 diabetes who cannot control blood sugar levels by diet and exercise alone. It may be used alone or with other antidiabetic medicines.

Glyburide Micronized is a sulfonylurea-type antidiabetic medicine. It works by stimulating the release of your body"s natural insulin from the pancreas, which in turn helps to lower your blood sugar.

Do NOT use Glyburide Micronized if:

you are allergic to any ingredient in Glyburide Micronized
you have certain problems associated with diabetes (eg, diabetic ketoacidosis, diabetic coma), severe burns, severe acidosis, or type 1 diabetes
you are in the late stages of pregnancy (at least 2 weeks before the expected delivery date)
you are taking bosentan

Contact your doctor or health care provider right away if any of these apply to you.

Before using Glyburide Micronized :

Some medical conditions may interact with Glyburide Micronized . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines or other substances
If you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
if you have liver, kidney, thyroid, or heart problems
if you have stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), severe diarrhea, or are malnourished
if you are debilitated, have a high fever, a severe infection, have suffered from severe trauma (eg, injury), or will be having surgery
if you have certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), an electrolyte imbalance, acidosis, or high blood pressure

Some MEDICINES MAY INTERACT with Glyburide Micronized . Tell your health care provider if you are taking any other medicines, especially any of the following:

Bosentan because liver problems may occur; the effectiveness of both medicines also may be decreased
Birth control pills, certain asthma medicine (eg, albuterol), calcium channel blockers (eg, diltiazem), corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diet pills, diuretics (eg, furosemide, hydrochlorothiazide, epinephrine, estrogens, isoniazid, miconazole, niacin, phenothiazines (eg, promethazine), rifamycins (eg, rifampin), seizure medicines (eg, phenytoin), or thyroid supplements (eg, levothyroxine) because the effects of Glyburide Micronized may be decreased
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), azole antifungals (eg, ketoconazole), beta-blockers (eg, propranolol), blood thinners (eg, warfarin), chloramphenicol, cimetidine, clofibrate, fenfluramine and derivatives, fluoxetine, macrolide antibiotics (eg, erythromycin), maprotiline, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nonsteroidal anti-inflammatory medicines (eg, ibuprofen), phenylbutazone, probenecid, quinidine, quinolone antibiotics (eg, ciprofloxacin), ranitidine, salicylates (eg, aspirin), and sulfonamides (eg, sulfamethoxazole) because side effects such as low blood sugar levels may be increased
Cyclosporine because side effects such as kidney harm may occur
Gemfibrozil because side effects such as increased or decreased blood sugar levels may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Glyburide Micronized may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Glyburide Micronized :

Use Glyburide Micronized as directed by your doctor. Check the label on the medicine for exact dosing instructions.

If you are taking 1 dose daily, take Glyburide Micronized with breakfast or your first main meal unless otherwise directed by your doctor.
Avoid excessive dietary fiber while taking Glyburide Micronized unless otherwise instructed by your health care provider.
Take Glyburide Micronized regularly to receive the most benefit from it.
Taking this medicine at the same time each day will help you to remember to take it.
If you miss a dose of Glyburide Micronized , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Glyburide Micronized .

Important safety information:

Glyburide Micronized may cause drowsiness, dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Glyburide Micronized . Using Glyburide Micronized alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
Avoid drinking alcoholic beverages while using Glyburide Micronized because they can increase the risk of developing hypoglycemia (low blood sugar). Rarely, alcohol can interact with Glyburide Micronized and cause a serious reaction (disulfiram-like reaction) with symptoms such as facial flushing, nausea, vomiting, dizziness, or stomach pain. Consult your doctor or pharmacist about the safe use of alcohol.
Glyburide Micronized may cause increased sensitivity to the sun. Avoid exposure to the sun or sunlamps until you know how you react to Glyburide Micronized . Use a sunscreen or protective clothing if you must be outside for a prolonged period.
Do not change from the micronized brand of Glyburide Micronized to the nonmicronized brand without consulting your pharmacist or doctor. They may not be equally effective.
Be sure to follow the diet and exercise program prescribed by your health care provider.
Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor"s directions. If your blood sugar level is often higher than it should be and you are taking this medicine according to directions, check with your doctor.
Glyburide Micronized may cause low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, fainting). It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you do not have a reliable source of glucose available, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or nondiet soda to quickly raise your blood sugar level. Tell your doctor immediately about the reaction. To prevent low blood sugar,, eat meals on a regular schedule and do not skip meals.
Use of similar medicines has been associated with an increased risk of heart problems. If you experience chest pain, irregular heartbeat, swelling in your hands or feet, or unusual or sudden weight gain, contact your doctor immediately. Talk to your doctor if you have any questions or concerns about taking Glyburide Micronized .
Monitor blood glucose levels on a regular basis. Contact your health care provider if high or low blood sugar levels develop.
Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are taking Glyburide Micronized .
During times of stress, such as fever, infection, injury, or surgery, it may be more difficult to control your blood sugar. Consult your doctor as a change in your medicine may be needed.
LAB TESTS, including liver function, kidney function, fasting blood glucose, glycosylated hemoglobin, and complete blood counts, may be performed to monitor your progress or to check for side effects. Keep all doctor and lab appointments.
Use caution in the ELDERLY because they may be more sensitive to the effects of Glyburide Micronized , especially abnormally low blood sugar levels.
Glyburide Micronized is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of taking Glyburide Micronized during pregnancy. If Glyburide Micronized is taken during pregnancy, it should be stopped at least 2 weeks before the expected delivery date to minimize the risk of severe low blood sugar in the newborn infant. It is unknown if Glyburide Micronized is excreted in breast milk. Do not breast-feed while taking Glyburide Micronized .

Possible side effects of Glyburide Micronized :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Allergic skin reactions; flushing; heartburn; itching; nausea; rash; redness; stomach fullness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; itching; dizziness); chest pain or irregular heartbeat; dark urine; easy bleeding/bruising; heart problems; high blood sugar levels (thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, fruity breath odor); mental/mood changes; persistent sore throat or fever; seizures; stomach pain; swelling of the hands or feet; unusual or sudden weight gain; unusual tiredness or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include coma; confusion; lethargy and impaired consciousness; light-headedness; loss of consciousness; mild stomach pain; nausea; rapid pulse; seizures (convulsions); sweating; tingling of the lips and tongue; tremor; vomiting.

Proper storage of Glyburide Micronized :

Store Glyburide Micronized at 59 to 86 degrees F (15 to 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Glyburide Micronized out of the reach of children and away from pets.

General information:

If you have any questions about Glyburide Micronized , please talk with your doctor, pharmacist, or other health care provider.
Glyburide Micronized is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Glyburide Micronized . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

Where can I get more information about Glyburide Micronized Glyburide Micronized ? We recommend to use www.Drugs.com

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