glatiramer injectable

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Copaxone, |glatiramer injectable

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glatiramer

Generic Name: glatiramer (injectable) (gla TEAR a mer)
Brand Names: Copaxone

What is glatiramer?

Glatiramer is a combination of four amino acids (proteins). It is believed to affect the immune system.

Glatiramer is used to decrease the frequency of relapses in patients with relapsing-remitting multiple sclerosis (MS).

Glatiramer may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about glatiramer?

Glatiramer is injected subcutaneously (under the skin). Your doctor or nurse will give you detailed instructions on how and where to inject glatiramer. Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you.

What should I discuss with my healthcare provider before using glatiramer?

Do not use glatiramer if you have an allergy to mannitol.

Before using this medication, tell your doctor if you have any other illness or if you take any other medicines. You may not be able to take glatiramer, or you may require a dosage adjustment or special monitoring during treatment.

Glatiramer is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether glatiramer passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should I use glatiramer?

Use glatiramer exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Glatiramer is injected subcutaneously (under the skin). Your doctor or nurse will give you detailed instructions on how and where to inject glatiramer. Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you.

Do not use any medication that is discolored or that has particles in it.

A prefilled syringe package should be allowed to stand at room temperature for 20 minutes to allow the solution to warm up to room temperature. To prevent the loss of medication, do not try to expel any air that is in the prefilled syringe before injecting the medication.

Wash and dry the hands before preparing or administering an injection.

To reconstitute the powdered form of glatiramer, add the diluent provided to the powdered material using a syringe as directed. Gently swirl the mixture and allow the solid material to completely dissolve at room temperature. Use the mixture immediately after mixing.

The premixed or reconstituted medicine should be injected into the skin of the thighs, back of the hips, back of the upper arms, or abdomen (about 2 inches on either side of the bellybutton). Rotate the injection site as directed. Use each injection site only once every 7 days. Injections should be administered at about the same time each day.

Do not change your dose or stop using this medication without first talking to your doctor.

The vials and prefilled syringes are designed for a single use only. Throw away any unused medication after each injection.

Never reuse a needle or syringe. Dispose of all needles and syringes in an appropriate, puncture-resistant disposal container.

Store the prefilled syringes and brown vials of glatiramer in the refrigerator at 36 to 46 degrees Fahrenheit (2 to 8 degrees Celsius). In extenuating circumstances, when refrigeration may not be available, the product may be allowed to reach room temperature, 59 to 86 degrees Fahrenheit (15 to 30 degrees Celsius) for up to one week. Avoid exposure to higher temperatures or intense light. Store the clear vials of the diluent (labeled "Sterile Water for Injection") at room temperature.

What happens if I miss a dose?

Inject the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and use only the next regularly scheduled dose. Do not inject a double dose of this medication unless otherwise directed.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a glatiramer overdose are not known.

What should I avoid while using glatiramer?

There are no specific restrictions on food, beverages, or activities during treatment with glatiramer. Follow any special instructions given by your doctor.

Glatiramer side effects

Stop using glatiramer and seek emergency medical attention or contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; chest pain; hives; skin rash with irritation; dizziness; sweating; or severe pain at the injection site).

Other less serious side effects may be more likely to occur. Notify your doctor if you experience

  • flushing, increased heart rate, or anxiety shortly following an injection;

  • fever or chills;

  • headache;

  • weakness or joint pain;

  • swelling or fluid retention;

  • redness, pain, inflammation, itching, or a lump at the injection site;

  • nausea, vomiting, or decreased appetite; or

  • diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect glatiramer?

It is not known if other drugs interact with glatiramer. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

  • Your pharmacist has additional information about glatiramer written for health professionals that you may read.

What does my medication look like?

Glatiramer is available with a prescription under the brand name Copaxone. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Copaxone 20 mg/mL prefilled syringes

  • Copaxone 20 mg vials

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with other, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 3.05. Revision Date: 8/11/04 2:46:53 PM.



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