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|Flumazenil Flumazenil

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Flumazenil

Generic Name: Flumazenil (FLOO-may-ze-nil)
Brand Name: Romazicon

Flumazenil may cause seizures, especially in patients who have been on benzodiazepines (eg, diazepam) for a long time or if a patient has taken too much of a benzodiazepine (overdose).

Flumazenil is used for:

Reversing drowsiness, sedation, and other effects caused by benzodiazepines.

Flumazenil is a benzodiazepine antagonist. It works by blocking receptors in the brain and central nervous system that benzodiazepines need to reach to be active, which helps reduce drowsiness and sedation.

Do NOT use Flumazenil if:

you are allergic to any ingredient in Flumazenil or to benzodiazepines (eg, alprazolam)
you have been given a benzodiazepine for control of a potentially life-threatening condition (eg, increased pressure in the head, seizures)
you are experiencing side effects due to an overdose of a medicine used to treat depression

Contact your doctor or health care provider right away if any of these apply to you.

Before using Flumazenil :

Some medical conditions may interact with Flumazenil . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine (especially benzodiazepines), herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of seizures, panic disorder, liver problems, alcohol or other substance abuse, or you have had a recent head injury

Some MEDICINES MAY INTERACT with Flumazenil . However, no specific interactions with Flumazenil are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Flumazenil may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Flumazenil :

Use Flumazenil as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Flumazenil is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Flumazenil at home, carefully follow the injection procedures taught to you by your health care provider.
If Flumazenil contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
If Flumazenil accidentally spills on your skin, wash it off immediately with soap and water.
Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
If you miss a dose of Flumazenil , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Flumazenil .

Important safety information:

Flumazenil may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Flumazenil . Using Flumazenil alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
Avoid drinking alcohol or taking other medicines that cause drowsiness (eg, sedatives, tranquilizers) for at least 24 hours after receiving Flumazenil . Flumazenil will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
Although Flumazenil is given to reverse drowsiness, you may experience a return of drowsiness for up to 24 hours after Flumazenil is given. If you notice a return of drowsiness or experience shortness of breath, contact your doctor as soon as possible.
Flumazenil is not recommended for use in CHILDREN younger than 1 year of age. Safety and effectiveness in this age group have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Flumazenil , discuss with your doctor the benefits and risks of using Flumazenil during pregnancy. It is unknown if Flumazenil is excreted in breast milk. If you are or will be breast-feeding while you are using Flumazenil , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Flumazenil :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal or blurred vision; abnormal skin sensations; changes in vision; clumsiness; dizziness; dry mouth; feeling of a whirling motion; flushing; general body discomfort; headache; hot flashes; increased sweating; nausea; nervousness; pain at the injection site; restlessness; sleeplessness; sweating; tiredness; tremors; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; change in behavior, mood, or emotions (eg, anxiety, depression); pounding in the chest; rapid deep breathing; seizures.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; anxiety; emotional or mood changes; increased sensitivity to pain or touch; seizures.

Proper storage of Flumazenil :

Flumazenil is usually handled and stored by a health care provider. If you are using Flumazenil at home, store Flumazenil as directed by your pharmacist or health care provider. Keep Flumazenil out of the reach of children and away from pets.

General information:

If you have any questions about Flumazenil , please talk with your doctor, pharmacist, or other health care provider.
Flumazenil is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Flumazenil . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

Where can I get more information about Flumazenil Flumazenil ? We recommend to use www.Drugs.com

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