Diphenoxylate Hydrochloride/Atropine Sulfate

drug-information.ru

|Diphenoxylate Hydrochloride/Atropine Sulfate

Drugs search, click the first letter of a drug name:


| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9  Home

Diphenoxylate Hydrochloride/Atropine Sulfate

Pronouncation: (die-fen-OX-ih-late HIGH-droe-KLOR-ide/AT-troe-peen SULL-fate)
Class: Antidiarrheal

Trade Names:
Logen
- Tablets 2.5 mg diphenoxylate HCl and 0.025 mg atropine sulfate

Trade Names:
Lomanate
- Liquid 2.5 mg diphenoxylate HCl and 0.025 mg atropine sulfate per 5 mL

Trade Names:
Lomotil
- Liquid 2.5 mg diphenoxylate HCl and 0.025 mg atropine sulfate per 5 mL
- Tablets 2.5 mg diphenoxylate HCl and 0.025 mg atropine sulfate

Trade Names:
Lonox
- Tablets 2.5 mg diphenoxylate HCl and 0.025 mg atropine sulfate

Mechanism of Action

Pharmacology

Diphenoxylate, related to meperidine, decreases motility of GI tract. Atropine discourages deliberate overdosage of diphenoxylate.

Indications and Usage

Adjunctive therapy in treatment of diarrhea.

Contraindications

Obstructive jaundice; diarrhea associated with pseudomembranous enterocolitis or enterotoxin-producing bacteria; narrow-angle glaucoma; use in children younger than 2 yr.

Dosage and Administration

Tablets may be crushed and administered with fluid.

Adults

Initial dose: PO 5 mg qid. Individualize dose.

Children 2 to 12 yr

PO 0.3 to 0.4 mg/kg/day in 4 divided doses.

Storage/Stability

Store in tightly closed, light-resistant container at room temperature.

Drug Interactions

Alcohol, barbiturates, CNS depressants, tranquilizers

May increase depressant action

MAOIs

May precipitate hypertensive crisis.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Cardiovascular

Tachycardia.

CNS

Dizziness; drowsiness; sedation; headache; malaise; lethargy; restlessness; euphoria; depression; numbness of extremities; confusion.

Dermatologic

Pruritus; angioneurotic edema; urticaria; dry skin and mucous membranes; flushing.

GI

Dry mouth; anorexia; nausea; vomiting; abdominal discomfort; paralytic ileus; toxic megacolon; pancreatitis; constipation.

Genitourinary

Urinary retention.

Miscellaneous

Swelling of gums; anaphylaxis; hyperthermia.

Precautions

Monitor

Assess frequency and consistency of stools before and throughout therapy. Monitor for signs of dehydration and toxic megacolon.


Pregnancy

Category B .

Lactation

Excreted in breast milk.

Children

Contraindicated in children younger than 2 yr. Greater risk of atropinism, especially with Down syndrome.

Hepatic Function

Use with extreme caution; may precipitate hepatic coma.

Diarrhea

Do not give for diarrhea associated with organisms that penetrate the intestinal mucosa (ie, Salmonella, Shigella), acute Crohn disease or pseudomembranous colitis caused by antibiotic therapy. Notify health care provider and discontinue therapy for abdominal distention or other untoward symptoms.

Fluid/electrolyte imbalance

Dehydration may contribute to adverse effects, especially in young children. If dehydration or electrolyte imbalance occurs, may need to discontinue therapy until condition is corrected.

Overdosage

Symptoms

Dry skin and mucous membranes, mydriasis, restlessness, flushing, hyperthermia, tachycardia, lethargy, coma, nystagmus, pinpoint pupils, respiratory depression.

Patient Information

  • Advise patient to continue taking drug until diarrhea has stopped for 24 to 36 hr. Discontinuing medication earlier may result in relapse or return of diarrhea.
  • Instruct patient to notify health care provider if fever and palpitations occur or when diarrhea persists or becomes malodorous or bloody.
  • Tell patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
  • Instruct patient to avoid intake of alcoholic beverages or other CNS depressants.
  • Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.




Where can I get more information about Diphenoxylate Hydrochloride/Atropine Sulfate ? We recommend to use www.Drugs.com

Typical mistypes for Diphenoxylate Hydrochloride/Atropine Sulfate
siphenoxylate hydrochloride/atropine sulfate, xiphenoxylate hydrochloride/atropine sulfate, ciphenoxylate hydrochloride/atropine sulfate, fiphenoxylate hydrochloride/atropine sulfate, riphenoxylate hydrochloride/atropine sulfate, eiphenoxylate hydrochloride/atropine sulfate, duphenoxylate hydrochloride/atropine sulfate, djphenoxylate hydrochloride/atropine sulfate, dkphenoxylate hydrochloride/atropine sulfate, dophenoxylate hydrochloride/atropine sulfate, d9phenoxylate hydrochloride/atropine sulfate, d8phenoxylate hydrochloride/atropine sulfate, diohenoxylate hydrochloride/atropine sulfate, dilhenoxylate hydrochloride/atropine sulfate, di-henoxylate hydrochloride/atropine sulfate, di0henoxylate hydrochloride/atropine sulfate, dipgenoxylate hydrochloride/atropine sulfate, dipbenoxylate hydrochloride/atropine sulfate, dipnenoxylate hydrochloride/atropine sulfate, dipjenoxylate hydrochloride/atropine sulfate, dipuenoxylate hydrochloride/atropine sulfate, dipyenoxylate hydrochloride/atropine sulfate, diphwnoxylate hydrochloride/atropine sulfate, diphsnoxylate hydrochloride/atropine sulfate, diphdnoxylate hydrochloride/atropine sulfate, diphrnoxylate hydrochloride/atropine sulfate, diph4noxylate hydrochloride/atropine sulfate, diph3noxylate hydrochloride/atropine sulfate, dipheboxylate hydrochloride/atropine sulfate, diphemoxylate hydrochloride/atropine sulfate, diphejoxylate hydrochloride/atropine sulfate, diphehoxylate hydrochloride/atropine sulfate, diphenixylate hydrochloride/atropine sulfate, diphenkxylate hydrochloride/atropine sulfate, diphenlxylate hydrochloride/atropine sulfate, diphenpxylate hydrochloride/atropine sulfate, diphen0xylate hydrochloride/atropine sulfate, diphen9xylate hydrochloride/atropine sulfate, diphenozylate hydrochloride/atropine sulfate, diphenocylate hydrochloride/atropine sulfate, diphenodylate hydrochloride/atropine sulfate, diphenosylate hydrochloride/atropine sulfate, diphenoxtlate hydrochloride/atropine sulfate, diphenoxglate hydrochloride/atropine sulfate, diphenoxhlate hydrochloride/atropine sulfate, diphenoxulate hydrochloride/atropine sulfate, diphenox7late hydrochloride/atropine sulfate, diphenox6late hydrochloride/atropine sulfate, diphenoxykate hydrochloride/atropine sulfate, diphenoxypate hydrochloride/atropine sulfate, diphenoxyoate hydrochloride/atropine sulfate, diphenoxylzte hydrochloride/atropine sulfate, diphenoxylste hydrochloride/atropine sulfate, diphenoxylwte hydrochloride/atropine sulfate, diphenoxylqte hydrochloride/atropine sulfate, diphenoxylare hydrochloride/atropine sulfate, diphenoxylafe hydrochloride/atropine sulfate, diphenoxylage hydrochloride/atropine sulfate, diphenoxylaye hydrochloride/atropine sulfate, diphenoxyla6e hydrochloride/atropine sulfate, diphenoxyla5e hydrochloride/atropine sulfate, diphenoxylatw hydrochloride/atropine sulfate, diphenoxylats hydrochloride/atropine sulfate, diphenoxylatd hydrochloride/atropine sulfate, diphenoxylatr hydrochloride/atropine sulfate, diphenoxylat4 hydrochloride/atropine sulfate, diphenoxylat3 hydrochloride/atropine sulfate, diphenoxylate gydrochloride/atropine sulfate, diphenoxylate bydrochloride/atropine sulfate, diphenoxylate nydrochloride/atropine sulfate, diphenoxylate jydrochloride/atropine sulfate, diphenoxylate uydrochloride/atropine sulfate, diphenoxylate yydrochloride/atropine sulfate, diphenoxylate htdrochloride/atropine sulfate, diphenoxylate hgdrochloride/atropine sulfate, diphenoxylate hhdrochloride/atropine sulfate, diphenoxylate hudrochloride/atropine sulfate, diphenoxylate h7drochloride/atropine sulfate, diphenoxylate h6drochloride/atropine sulfate, diphenoxylate hysrochloride/atropine sulfate, diphenoxylate hyxrochloride/atropine sulfate, diphenoxylate hycrochloride/atropine sulfate, diphenoxylate hyfrochloride/atropine sulfate, diphenoxylate hyrrochloride/atropine sulfate, diphenoxylate hyerochloride/atropine sulfate, diphenoxylate hydeochloride/atropine sulfate, diphenoxylate hyddochloride/atropine sulfate, diphenoxylate hydfochloride/atropine sulfate, diphenoxylate hydtochloride/atropine sulfate, diphenoxylate hyd5ochloride/atropine sulfate, diphenoxylate hyd4ochloride/atropine sulfate, diphenoxylate hydrichloride/atropine sulfate, diphenoxylate hydrkchloride/atropine sulfate, diphenoxylate hydrlchloride/atropine sulfate, diphenoxylate hydrpchloride/atropine sulfate, diphenoxylate hydr0chloride/atropine sulfate, diphenoxylate hydr9chloride/atropine sulfate, diphenoxylate hydroxhloride/atropine sulfate, diphenoxylate hydrovhloride/atropine sulfate, diphenoxylate hydrofhloride/atropine sulfate, diphenoxylate hydrodhloride/atropine sulfate, diphenoxylate hydrocgloride/atropine sulfate, diphenoxylate hydrocbloride/atropine sulfate, diphenoxylate hydrocnloride/atropine sulfate, diphenoxylate hydrocjloride/atropine sulfate, diphenoxylate hydroculoride/atropine sulfate, diphenoxylate hydrocyloride/atropine sulfate, diphenoxylate hydrochkoride/atropine sulfate, diphenoxylate hydrochporide/atropine sulfate, diphenoxylate hydrochooride/atropine sulfate, diphenoxylate hydrochliride/atropine sulfate, diphenoxylate hydrochlkride/atropine sulfate, diphenoxylate hydrochllride/atropine sulfate, diphenoxylate hydrochlpride/atropine sulfate, diphenoxylate hydrochl0ride/atropine sulfate, diphenoxylate hydrochl9ride/atropine sulfate, diphenoxylate hydrochloeide/atropine sulfate, diphenoxylate hydrochlodide/atropine sulfate, diphenoxylate hydrochlofide/atropine sulfate, diphenoxylate hydrochlotide/atropine sulfate, diphenoxylate hydrochlo5ide/atropine sulfate, diphenoxylate hydrochlo4ide/atropine sulfate, diphenoxylate hydrochlorude/atropine sulfate, diphenoxylate hydrochlorjde/atropine sulfate, diphenoxylate hydrochlorkde/atropine sulfate, diphenoxylate hydrochlorode/atropine sulfate, diphenoxylate hydrochlor9de/atropine sulfate, diphenoxylate hydrochlor8de/atropine sulfate, diphenoxylate hydrochlorise/atropine sulfate, diphenoxylate hydrochlorixe/atropine sulfate, diphenoxylate hydrochlorice/atropine sulfate, diphenoxylate hydrochlorife/atropine sulfate, diphenoxylate hydrochlorire/atropine sulfate, diphenoxylate hydrochloriee/atropine sulfate, diphenoxylate hydrochloridw/atropine sulfate, diphenoxylate hydrochlorids/atropine sulfate, diphenoxylate hydrochloridd/atropine sulfate, diphenoxylate hydrochloridr/atropine sulfate, diphenoxylate hydrochlorid4/atropine sulfate, diphenoxylate hydrochlorid3/atropine sulfate, diphenoxylate hydrochloride/ztropine sulfate, diphenoxylate hydrochloride/stropine sulfate, diphenoxylate hydrochloride/wtropine sulfate, diphenoxylate hydrochloride/qtropine sulfate, diphenoxylate hydrochloride/arropine sulfate, diphenoxylate hydrochloride/afropine sulfate, diphenoxylate hydrochloride/agropine sulfate, diphenoxylate hydrochloride/ayropine sulfate, diphenoxylate hydrochloride/a6ropine sulfate, diphenoxylate hydrochloride/a5ropine sulfate, diphenoxylate hydrochloride/ateopine sulfate, diphenoxylate hydrochloride/atdopine sulfate, diphenoxylate hydrochloride/atfopine sulfate, diphenoxylate hydrochloride/attopine sulfate, diphenoxylate hydrochloride/at5opine sulfate, diphenoxylate hydrochloride/at4opine sulfate, diphenoxylate hydrochloride/atripine sulfate, diphenoxylate hydrochloride/atrkpine sulfate, diphenoxylate hydrochloride/atrlpine sulfate, diphenoxylate hydrochloride/atrppine sulfate, diphenoxylate hydrochloride/atr0pine sulfate, diphenoxylate hydrochloride/atr9pine sulfate, diphenoxylate hydrochloride/atrooine sulfate, diphenoxylate hydrochloride/atroline sulfate, diphenoxylate hydrochloride/atro-ine sulfate, diphenoxylate hydrochloride/atro0ine sulfate, diphenoxylate hydrochloride/atropune sulfate, diphenoxylate hydrochloride/atropjne sulfate, diphenoxylate hydrochloride/atropkne sulfate, diphenoxylate hydrochloride/atropone sulfate, diphenoxylate hydrochloride/atrop9ne sulfate, diphenoxylate hydrochloride/atrop8ne sulfate, diphenoxylate hydrochloride/atropibe sulfate, diphenoxylate hydrochloride/atropime sulfate, diphenoxylate hydrochloride/atropije sulfate, diphenoxylate hydrochloride/atropihe sulfate, diphenoxylate hydrochloride/atropinw sulfate, diphenoxylate hydrochloride/atropins sulfate, diphenoxylate hydrochloride/atropind sulfate, diphenoxylate hydrochloride/atropinr sulfate, diphenoxylate hydrochloride/atropin4 sulfate, diphenoxylate hydrochloride/atropin3 sulfate, diphenoxylate hydrochloride/atropine aulfate, diphenoxylate hydrochloride/atropine zulfate, diphenoxylate hydrochloride/atropine xulfate, diphenoxylate hydrochloride/atropine dulfate, diphenoxylate hydrochloride/atropine eulfate, diphenoxylate hydrochloride/atropine wulfate, diphenoxylate hydrochloride/atropine sylfate, diphenoxylate hydrochloride/atropine shlfate, diphenoxylate hydrochloride/atropine sjlfate, diphenoxylate hydrochloride/atropine silfate, diphenoxylate hydrochloride/atropine s8lfate, diphenoxylate hydrochloride/atropine s7lfate, diphenoxylate hydrochloride/atropine sukfate, diphenoxylate hydrochloride/atropine supfate, diphenoxylate hydrochloride/atropine suofate, diphenoxylate hydrochloride/atropine suldate, diphenoxylate hydrochloride/atropine sulcate, diphenoxylate hydrochloride/atropine sulvate, diphenoxylate hydrochloride/atropine sulgate, diphenoxylate hydrochloride/atropine sultate, diphenoxylate hydrochloride/atropine sulrate, diphenoxylate hydrochloride/atropine sulfzte, diphenoxylate hydrochloride/atropine sulfste, diphenoxylate hydrochloride/atropine sulfwte, diphenoxylate hydrochloride/atropine sulfqte, diphenoxylate hydrochloride/atropine sulfare, diphenoxylate hydrochloride/atropine sulfafe, diphenoxylate hydrochloride/atropine sulfage, diphenoxylate hydrochloride/atropine sulfaye, diphenoxylate hydrochloride/atropine sulfa6e, diphenoxylate hydrochloride/atropine sulfa5e, diphenoxylate hydrochloride/atropine sulfatw, diphenoxylate hydrochloride/atropine sulfats, diphenoxylate hydrochloride/atropine sulfatd, diphenoxylate hydrochloride/atropine sulfatr, diphenoxylate hydrochloride/atropine sulfat4, diphenoxylate hydrochloride/atropine sulfat3, iphenoxylate hydrochloride/atropine sulfate, dphenoxylate hydrochloride/atropine sulfate, dihenoxylate hydrochloride/atropine sulfate, dipenoxylate hydrochloride/atropine sulfate, diphnoxylate hydrochloride/atropine sulfate, dipheoxylate hydrochloride/atropine sulfate, diphenxylate hydrochloride/atropine sulfate, diphenoylate hydrochloride/atropine sulfate, diphenoxlate hydrochloride/atropine sulfate, diphenoxyate hydrochloride/atropine sulfate, diphenoxylte hydrochloride/atropine sulfate, diphenoxylae hydrochloride/atropine sulfate, diphenoxylat hydrochloride/atropine sulfate, diphenoxylatehydrochloride/atropine sulfate, diphenoxylate ydrochloride/atropine sulfate, diphenoxylate hdrochloride/atropine sulfate, diphenoxylate hyrochloride/atropine sulfate, diphenoxylate hydochloride/atropine sulfate, diphenoxylate hydrchloride/atropine sulfate, diphenoxylate hydrohloride/atropine sulfate, diphenoxylate hydrocloride/atropine sulfate, diphenoxylate hydrochoride/atropine sulfate, diphenoxylate hydrochlride/atropine sulfate, diphenoxylate hydrochloide/atropine sulfate, diphenoxylate hydrochlorde/atropine sulfate, diphenoxylate hydrochlorie/atropine sulfate, diphenoxylate hydrochlorid/atropine sulfate, diphenoxylate hydrochlorideatropine sulfate, diphenoxylate hydrochloride/tropine sulfate, diphenoxylate hydrochloride/aropine sulfate, diphenoxylate hydrochloride/atopine sulfate, diphenoxylate hydrochloride/atrpine sulfate, diphenoxylate hydrochloride/atroine sulfate, diphenoxylate hydrochloride/atropne sulfate, diphenoxylate hydrochloride/atropie sulfate, diphenoxylate hydrochloride/atropin sulfate, diphenoxylate hydrochloride/atropinesulfate, diphenoxylate hydrochloride/atropine ulfate, diphenoxylate hydrochloride/atropine slfate, diphenoxylate hydrochloride/atropine sufate, diphenoxylate hydrochloride/atropine sulate, diphenoxylate hydrochloride/atropine sulfte, diphenoxylate hydrochloride/atropine sulfae, diphenoxylate hydrochloride/atropine sulfat, idphenoxylate hydrochloride/atropine sulfate, dpihenoxylate hydrochloride/atropine sulfate, dihpenoxylate hydrochloride/atropine sulfate, dipehnoxylate hydrochloride/atropine sulfate, diphneoxylate hydrochloride/atropine sulfate, dipheonxylate hydrochloride/atropine sulfate, diphenxoylate hydrochloride/atropine sulfate, diphenoyxlate hydrochloride/atropine sulfate, diphenoxlyate hydrochloride/atropine sulfate, diphenoxyalte hydrochloride/atropine sulfate, diphenoxyltae hydrochloride/atropine sulfate, diphenoxylaet hydrochloride/atropine sulfate, diphenoxylat ehydrochloride/atropine sulfate, diphenoxylateh ydrochloride/atropine sulfate, diphenoxylate yhdrochloride/atropine sulfate, diphenoxylate hdyrochloride/atropine sulfate, diphenoxylate hyrdochloride/atropine sulfate, diphenoxylate hydorchloride/atropine sulfate, diphenoxylate hydrcohloride/atropine sulfate, diphenoxylate hydrohcloride/atropine sulfate, diphenoxylate hydroclhoride/atropine sulfate, diphenoxylate hydrocholride/atropine sulfate, diphenoxylate hydrochlroide/atropine sulfate, diphenoxylate hydrochloirde/atropine sulfate, diphenoxylate hydrochlordie/atropine sulfate, diphenoxylate hydrochloried/atropine sulfate, diphenoxylate hydrochlorid/eatropine sulfate, diphenoxylate hydrochloridea/tropine sulfate, diphenoxylate hydrochloride/taropine sulfate, diphenoxylate hydrochloride/artopine sulfate, diphenoxylate hydrochloride/atorpine sulfate, diphenoxylate hydrochloride/atrpoine sulfate, diphenoxylate hydrochloride/atroipne sulfate, diphenoxylate hydrochloride/atropnie sulfate, diphenoxylate hydrochloride/atropien sulfate, diphenoxylate hydrochloride/atropin esulfate, diphenoxylate hydrochloride/atropines ulfate, diphenoxylate hydrochloride/atropine uslfate, diphenoxylate hydrochloride/atropine slufate, diphenoxylate hydrochloride/atropine suflate, diphenoxylate hydrochloride/atropine sulafte, diphenoxylate hydrochloride/atropine sulftae, diphenoxylate hydrochloride/atropine sulfaet, ddiphenoxylate hydrochloride/atropine sulfate, diiphenoxylate hydrochloride/atropine sulfate, dipphenoxylate hydrochloride/atropine sulfate, diphhenoxylate hydrochloride/atropine sulfate, dipheenoxylate hydrochloride/atropine sulfate, diphennoxylate hydrochloride/atropine sulfate, diphenooxylate hydrochloride/atropine sulfate, diphenoxxylate hydrochloride/atropine sulfate, diphenoxyylate hydrochloride/atropine sulfate, diphenoxyllate hydrochloride/atropine sulfate, diphenoxylaate hydrochloride/atropine sulfate, diphenoxylatte hydrochloride/atropine sulfate, diphenoxylatee hydrochloride/atropine sulfate, diphenoxylate hydrochloride/atropine sulfate, diphenoxylate hhydrochloride/atropine sulfate, diphenoxylate hyydrochloride/atropine sulfate, diphenoxylate hyddrochloride/atropine sulfate, diphenoxylate hydrrochloride/atropine sulfate, diphenoxylate hydroochloride/atropine sulfate, diphenoxylate hydrocchloride/atropine sulfate, diphenoxylate hydrochhloride/atropine sulfate, diphenoxylate hydrochlloride/atropine sulfate, diphenoxylate hydrochlooride/atropine sulfate, diphenoxylate hydrochlorride/atropine sulfate, diphenoxylate hydrochloriide/atropine sulfate, diphenoxylate hydrochloridde/atropine sulfate, diphenoxylate hydrochloridee/atropine sulfate, diphenoxylate hydrochloride//atropine sulfate, diphenoxylate hydrochloride/aatropine sulfate, diphenoxylate hydrochloride/attropine sulfate, diphenoxylate hydrochloride/atrropine sulfate, diphenoxylate hydrochloride/atroopine sulfate, diphenoxylate hydrochloride/atroppine sulfate, diphenoxylate hydrochloride/atropiine sulfate, diphenoxylate hydrochloride/atropinne sulfate, diphenoxylate hydrochloride/atropinee sulfate, diphenoxylate hydrochloride/atropine sulfate, diphenoxylate hydrochloride/atropine ssulfate, diphenoxylate hydrochloride/atropine suulfate, diphenoxylate hydrochloride/atropine sullfate, diphenoxylate hydrochloride/atropine sulffate, diphenoxylate hydrochloride/atropine sulfaate, diphenoxylate hydrochloride/atropine sulfatte, diphenoxylate hydrochloride/atropine sulfatee, etc.



© Copyright by drug-information.ru 2001-2019. All rights reserved