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|Depo-Sub Q Provera Injectable Suspension

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Depo-Sub Q Provera Injectable Suspension (subcutaneous)

Generic Name: Medroxyprogesterone Injectable Suspension (subcutaneous) (meh-DROX-ee-pro-JESS-tuh-rone)
Brand Name: Depo-Sub Q Provera

Depo-Sub Q Provera Injectable Suspension (subcutaneous) may decrease the amount of calcium in your bones. The longer you use Depo-Sub Q Provera Injectable Suspension (subcutaneous), the more calcium you are likely to lose. The calcium may not return completely once you stop using Depo-Sub Q Provera Injectable Suspension (subcutaneous). Loss of bone calcium may cause weak bones (osteoporosis). This could increase the risk of bone fracture, especially after menopause. It is not known if using Depo-Sub Q Provera Injectable Suspension (subcutaneous) during adolescence or early adulthood will increase your chances of developing osteoporosis later in life. Depo-Sub Q Provera Injectable Suspension (subcutaneous) should be used as a long-term birth control method (more than 2 years) only if other birth control methods are not right for you.

Depo-Sub Q Provera Injectable Suspension (subcutaneous) is used for:

Management of pain associated with endometriosis, prevention of pregnancy, and certain conditions as determined by your doctor that may not be listed in the professional package insert.

Depo-Sub Q Provera Injectable Suspension (subcutaneous) is a progestin hormone. It works by inhibiting chemicals released from the brain, which normally stimulate the ovaries to produce eggs. It also alters the lining of the uterus so it is less likely to accept a fertilized egg. These effects work together to reduce the chance of pregnancy occurring after intercourse.

Do NOT use Depo-Sub Q Provera Injectable Suspension (subcutaneous) if:

you are allergic to any ingredient in Depo-Sub Q Provera Injectable Suspension (subcutaneous)
you have a history of bleeding in the brain or stroke, breast cancer, undiagnosed vaginal bleeding,or blood clots
you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Depo-Sub Q Provera Injectable Suspension (subcutaneous):

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

if you are planning to become pregnant or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have diabetes or depression

Some MEDICINES MAY INTERACT with Depo-Sub Q Provera Injectable Suspension (subcutaneous). Tell your health care provider if you are taking any of the following medicines.

Rifampin because the effects of Depo-Sub Q Provera Injectable Suspension (subcutaneous) may be decreased and side effects, such as menstrual irregularities (spotting, breakthrough bleeding, loss of menses, and/or pregnancy), may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Depo-Sub Q Provera Injectable Suspension (subcutaneous) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Depo-Sub Q Provera Injectable Suspension (subcutaneous):

Use Depo-Sub Q Provera Injectable Suspension (subcutaneous) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Depo-Sub Q Provera Injectable Suspension (subcutaneous) is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Depo-Sub Q Provera Injectable Suspension (subcutaneous) at home, carefully follow the injection procedures taught to you by your health care provider.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) comes with an additional patient leaflet. Read it carefully and reread it each time you get Depo-Sub Q Provera Injectable Suspension (subcutaneous) refilled.
If the medicine contains particles or is discolored, or if the vial/container is cracked or damaged in any way, do not use it.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) is given every 3 months. It is very important that you return to your doctor"s office for your next injection promptly at the end of the 3-month interval.
If you miss a dose of Depo-Sub Q Provera Injectable Suspension (subcutaneous), contact your doctor as soon as possible.

Ask your health care provider any questions you may have about how to use Depo-Sub Q Provera Injectable Suspension (subcutaneous).

Important safety information:

Depo-Sub Q Provera Injectable Suspension (subcutaneous) may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Depo-Sub Q Provera Injectable Suspension (subcutaneous). Using Depo-Sub Q Provera Injectable Suspension (subcutaneous) alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) may cause a decrease in the amount of calcium in your bones. A decrease in bone calcium is of most concern if you have the following risk factors: adolescence, bone disease, anorexia nervosa (an eating disorder), a strong family history of osteoporosis, if you take certain medicines (eg, for epilepsy or steroids), or if you drink a lot of alcohol or smoke cigarettes often. If you need a birth control method for more than 2 years, your health care provider may switch you to another method or test you for weak bones. When Depo-Sub Q Provera Injectable Suspension (subcutaneous) is stopped, the calcium in bones begins to come back. Your health care provider may recommend that you take calcium or vitamin D to help lower the amount of calcium lost from your bones.
Diabetes patients - Depo-Sub Q Provera Injectable Suspension (subcutaneous) may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Depo-Sub Q Provera Injectable Suspension (subcutaneous) if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Depo-Sub Q Provera Injectable Suspension (subcutaneous) is excreted in breast milk. If you are or will be breast-feeding while you are using Depo-Sub Q Provera Injectable Suspension (subcutaneous), check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Depo-Sub Q Provera Injectable Suspension (subcutaneous):

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; dizziness; drowsiness; fever; headache; hot flashes;nausea; nervousness; pain; rash; sleeplessness; stomach pain; weakness; weight gain or loss.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood clots; chest pain; depression; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache; swelling of fingers or ankles; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Depo-Sub Q Provera Injectable Suspension (subcutaneous):

Store Depo-Sub Q Provera Injectable Suspension (subcutaneous) at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep Depo-Sub Q Provera Injectable Suspension (subcutaneous) out of the reach of children and away from pets.

General information:

If you have any questions about Depo-Sub Q Provera Injectable Suspension (subcutaneous), please talk with your doctor, pharmacist, or other health care provider.
Depo-Sub Q Provera Injectable Suspension (subcutaneous) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Depo-Sub Q Provera Injectable Suspension (subcutaneous). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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