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Demerol HCl, |Demerol HCl

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Demerol HCl

Generic Name: meperidine (me PER i deen)
Brand Names: Demerol HCl

What is meperidine?

Meperidine is in a class of drugs called narcotic analgesics. It relieves pain.

Meperidine is used to treat moderate-to-severe pain.

Meperidine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about meperidine?

Meperidine may increase the effects of other drugs that cause drowsiness, including other pain relievers, alcohol, antihistamines, sedatives (used to treat insomnia), antidepressants, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Meperidine may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in the diet can also help to alleviate constipation.

Never take more meperidine than is prescribed. If the pain is not being adequately treated, talk to your doctor.

What should I discuss with my healthcare provider before taking meperidine?

Meperidine may be habit forming and should only be used under close supervision if there is a history of alcohol or drug addiction.

Before taking this medication, tell your doctor if you have

kidney disease;
liver disease;
asthma;
urinary retention;
an enlarged prostate;
hypothyroidism;
seizures or epilepsy;
gallbladder disease;
a head injury; or
Addison"s disease.

You may not be able to take meperidine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Meperidine may cause addiction and withdrawal symptoms as well as other harmful effects in an unborn baby. Do not take meperidine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Meperidine may also cause addiction and withdrawal symptoms in a nursing infant. Do not take meperidine without first talking to your doctor if you are breast-feeding a baby.

How should I take meperidine?

Take meperidine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take meperidine with food or milk if it causes stomach upset.

To ensure that you get a correct dose, measure the syrup with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Meperidine is also available as an injection. Your healthcare provider will administer injectable meperidine. If you are using injectable meperidine at home, your healthcare provider will give you detailed instructions regarding preparation, administration, and storage of the medication.

Never take more meperidine than is prescribed. If the pain is not being adequately treated, talk to your doctor.

Meperidine may be habit forming. Physical and/or psychological dependence can occur, and withdrawal effects are possible if the medication is stopped suddenly after prolonged or high-dose treatment. Do not stop taking meperidine suddenly without first talking to your doctor if you have been taking it continuously for more than 5 to 7 days. Your doctor may want to gradually reduce the dose. Meperidine may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in the diet can also help to alleviate constipation.

Do not share this medication with anyone else.

Store meperidine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking the next dose.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a meperidine overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, and small pupils.

What should I avoid while taking meperidine?

Use caution when driving, operating machinery, or performing other hazardous activities. Meperidine may cause drowsiness. If you experience drowsiness, avoid these activities. Avoid alcohol while taking meperidine. Alcohol may increase the drowsiness and dizziness caused by meperidine and could be dangerous.

Meperidine side effects

If you experience any of the following serious side effects, stop taking meperidine and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
slow, weak breathing;
seizures;
cold, clammy skin;
severe weakness or dizziness; or
unconsciousness.

Other, less serious side effects may be more likely to occur. Continue to take meperidine and talk to your doctor if you experience

constipation;
dry mouth, nausea, vomiting, or decreased appetite;
dizziness, tiredness, or lightheadedness;
muscle twitches;
sweating;
itching;
decreased urination; or
decreased sex drive.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect meperidine?

Do not take meperidine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Drugs other than those listed here may also interact with meperidine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about meperidine written for health professionals that you may read.

What does my medication look like?

Meperidine is available with a prescription generically and under the brand name Demerol. Other formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Demerol 50 mg--white, round, convex, scored tablets
Demerol 100 mg--white, round, convex tablets
Demerol Syrup 50 mg per 5 mL (1 teaspoon)--banana flavored

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 4.05. Revision Date: 2/24/06 10:37:33 AM.

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