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|Crestor

Crestor

Crestor is used for:

Lowering cholesterol and triglyceride levels and increasing "good" cholesterol (high-density lipoprotein [HDL]) levels in patients who have also adopted lifestyle changes (eg, diet and exercise).

Crestor is an HMG-CoA reductase inhibitor (statin). It works in conjunction with diet and exercise by reducing the production of triglycerides in the liver.

Do NOT use Crestor if:

• you are allergic to any ingredient in Crestor
• you have liver problems or unexplained abnormal liver function test results
• you are pregnant or breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Crestor :

Some medical conditions may interact with Crestor . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have alcoholism or have a history of alcohol abuse
• if you have a history of muscle problems or weakness, heart problems, kidney problems, an underactive thyroid, low blood pressure, dehydration, a severe infection, an infection of the blood, seizures, liver problems, or diabetes; metabolism, endocrine, or electrolyte problems; high levels of the enzyme creatine phosphokinase; or a family history of muscle problems
• if you have had recent trauma or surgery (including organ transplant)

Some MEDICINES MAY INTERACT with Crestor . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cyclosporine, fibrates (eg, clofibrate), gemfibrozil, or niacin because they may increase the risk of Crestor "s side effects
• Anticoagulants (eg, warfarin), cimetidine, ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Crestor

This may not be a complete list of all interactions that may occur. Ask your health care provider if Crestor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Crestor :

Use Crestor as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Crestor may be taken with or without food.
• Do not take antacids for at least 2 hours after taking Crestor .
• It is important to continue to take Crestor even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.
• Crestor should be taken regularly to get the most benefit from it. Taking Crestor at the same time each day will help you remember to take it.
• If you miss a dose of Crestor , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Crestor .

Important safety information:

• Crestor may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Crestor . Using Crestor alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Crestor .
• Limit use of alcohol-containing beverages. Daily use of alcohol may increase your chance for serious side effects.
• Use Crestor with caution in Asian patients because they may be more sensitive to its effects, especially effects on the muscles that may lead to kidney problems.
• If you are able to become pregnant, talk with your doctor or pharmacist about the use of effective birth control while taking Crestor .
• LAB TESTS, including liver function, kidney function, and blood cholesterol levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Crestor with caution in the ELDERLY because they may be more sensitive to its effects, especially muscle problems.
• Use Crestor with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Do not use Crestor if you are pregnant. Crestor may cause harm to the fetus. Avoid becoming pregnant while taking Crestor . If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if Crestor is excreted in breast milk. Do not breast-feed while taking Crestor .

Possible side effects of Crestor :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; constipation; diarrhea; headache; indigestion; nausea; runny nose; sinus inflammation; sore throat; stomach upset; weakness.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; decreased or painful urination; fever; general body discomfort; muscle pain, cramping, tenderness, or weakness (especially with fever or unusual tiredness); severe or persistent nausea; stomach pain; swelling of the arms or legs; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Store Crestor at room temperature, between 68 and 77 degrees F (20 to 25 degrees C). Store away from heat, moisture, and light. Keep Crestor out of the reach of children and away from pets.

General information:

• If you have any questions about Crestor , please talk with your doctor, pharmacist, or other health care provider.
• Crestor is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Crestor . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.