Cortisporin Solution

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Cortisporin Solution


Generic Name: Hydrocortisone/Neomycin/Polymyxin B Ear Solution (hye-droe-KOR-ti-sone/nee-oh-MYE-sin/pol-i-MIX-in)
Brand Name: Examples include Cortisporin and Cortomycin

Cortisporin Solution is used for:

Treating infections of the ear caused by certain bacteria. It may also be used for other conditions as determined by your doctor.

Cortisporin Solution is a combination of 2 antibiotics and a corticosteroid. The antibiotics work by slowing the growth of, or killing, sensitive bacteria. The corticosteroid reduces inflammation.

Do NOT use Cortisporin Solution if:

  • you are allergic to any ingredient in Cortisporin Solution, to other aminoglycosides (eg, gentamicin), or to other corticosteroids (eg, prednisone)
  • you have a viral infection of the ear (eg, herpes simplex, chickenpox, shingles)
  • you have a perforated ear drum

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cortisporin Solution:

Some medical conditions may interact with Cortisporin Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma

Some MEDICINES MAY INTERACT with Cortisporin Solution. Because little, if any, of Cortisporin Solution is absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cortisporin Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cortisporin Solution:

Use Cortisporin Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cortisporin Solution is for use in the ear. Do not get Cortisporin Solution in your eyes. If you get Cortisporin Solution in your eyes, rinse immediately with cool tap water.
  • Wash your hands thoroughly before and after using Cortisporin Solution.
  • Wash and dry the outer ear with a sterile cotton applicator.
  • To use ear drops, lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for 5 minutes so the medicine can run to the bottom of the ear canal. A clean cotton plug may be gently inserted into the ear canal to prevent medicine from leaking out. To prevent germs from contaminating the medicine, do not touch the applicator to any surface, including the ear. Keep the container tightly closed.
  • To clear up your infection completely, continue using Cortisporin Solution for the full course of treatment even if you feel better in a few days.
  • If you miss a dose of Cortisporin Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cortisporin Solution.

Important safety information:

  • Cortisporin Solution is effective only against bacteria. It is not useful against fungal or viral infections.
  • It is important to use Cortisporin Solution for the full course of treatment. Failure to do so may decrease the effectiveness of Cortisporin Solution and may increase the risk that the bacteria will no longer be sensitive to Cortisporin Solution and will not be able to be treated by this or certain other antibiotics in the future.
  • Long-term or repeated use of Cortisporin Solution may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
  • If your condition does not improve within 7 days or if it becomes worse, check with your doctor.
  • Do not exceed the recommended dose or use Cortisporin Solution for longer than 10 days without checking with your doctor.
  • Do not use Cortisporin Solution for other ear conditions at a later time.
  • Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Cortisporin Solution.
  • Use Cortisporin Solution with extreme caution in CHILDREN younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Cortisporin Solution during pregnancy. It is unknown if Cortisporin Solution is excreted in breast milk after topical use. If you are or will be breast-feeding while you are using Cortisporin Solution, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Cortisporin Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild, temporary burning or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; changes in hearing; decreased urination; dry, scaly, or peeling skin at the application site; continued burning or stinging; excessive hair growth; inflamed hair follicles; inflammation around the mouth; loss of hearing; muscle weakness; pain, redness, itching, irritation, or swelling not present when you began using Cortisporin Solution; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Cortisporin Solution:

Store Cortisporin Solution between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Keep Cortisporin Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Cortisporin Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Cortisporin Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cortisporin Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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