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|Colrex Compound Coly-Mycin

Colrex Compound

Colrex Compound is used for:

Treating symptoms of the common cold, flu, or hay fever, and other upper respiratory allergies such as cough, congestion, runny nose, pain, fever, sneezing, itching of the nose and throat, and itchy, watery eyes. Colrex Compound may also be used for other conditions as determined by your doctor.

Colrex Compound is a narcotic antitussive (cough suppressant), analgesic, antihistamine, and decongestant combination. The antitussive works by suppressing the cough center in the brain. The analgesic works in the brain to reduce pain and fever. The antihistamine works by blocking the action of histamine, which reduces the symptoms of an allergic reaction such as itch, watery eyes and runny nose. The decongestant shrinks swollen nasal passages, which relieves nasal congestion.

Do NOT use Colrex Compound if:

• you are allergic to any ingredient in Colrex Compound or any other codeine-related medicine (eg, dihydrocodeine)
• you have diarrhea associated with poisoning, antibiotic use, or a bacterial infection (from eating or drinking contaminated food or water)
• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
• you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Colrex Compound :

Some medical conditions may interact with Colrex Compound . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol or drug abuse, dependence on narcotics, or suicidal thoughts or behaviors
• if you have increased pressure in the head, an unusual growth in the brain (eg, tumor), a recent head injury, Parkinson disease, Reye syndrome, the blood disease porphyria, or a blockage of your stomach, bowel, or bladder
• if you have a history of epilepsy or seizures, asthma or other breathing problems (eg, sleep apnea), stomach or intestinal problems, chronic constipation, liver problems (eg, hepatitis), severe kidney problems, glaucoma, an enlarged prostate gland or other prostate problems, difficulty urinating, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, overactive thyroid, seizures, or stroke
• if you have recently had abdominal surgery

Some MEDICINES MAY INTERACT with Colrex Compound . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturate anesthetics (eg, thiopental), beta-blockers (eg, propranolol), cimetidine, catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, ketorolac, MAO inhibitors (eg, phenelzine), naltrexone, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Colrex Compound may be increased, including dangerous sleepiness and a decrease in the ability to breathe
• Anticoagulants (eg, warfarin) or isoniazid because the risk of bleeding or liver problems may be increased
• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
• Rifampin or risperidone because the effectiveness of Colrex Compound may be decreased
• Bromocriptine or hydantoins (eg, phenytoin) because the actions and side effects may be increased by Colrex Compound
• Guanadrel, guanethidine, mecamylamine, methyldopa, mexiletine, or reserpine because the effectiveness may be decreased by Colrex Compound
• Naltrexone because the effectiveness of Colrex Compound will be decreased and withdrawal symptoms may occur in patients who have become physically dependent on opioids. You must not take naltrexone until you have stopped taking Colrex Compound for 7 to 10 days and after a naloxone challenge test is negative.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Colrex Compound may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Colrex Compound :

Use Colrex Compound as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Colrex Compound may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• If you miss a dose of Colrex Compound and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Colrex Compound .

Important safety information:

• Colrex Compound may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Colrex Compound . Using Colrex Compound alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Do not drink alcohol while you are using Colrex Compound . Avoid taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Colrex Compound . Colrex Compound will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• If your symptoms do not improve within 7 days or if you develop a high fever or persistent headache, check with your doctor.
• Use Colrex Compound with caution in the ELDERLY because they may be more sensitive to its effects, especially possible breathing problems and drowsiness.
• Use Colrex Compound with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is unknown if Colrex Compound can cause harm to the fetus. If you become pregnant while taking Colrex Compound , discuss with your doctor the benefits and risks of using Colrex Compound during pregnancy. Colrex Compound is excreted in breast milk. If you are or will be breast-feeding while you are using Colrex Compound , check with your doctor or pharmacist to discuss the risks to your baby.

Use of Colrex Compound can lead to TOLERANCE. When using for an extended period, Colrex Compound may not work as well and may require different dosing. Talk with your doctor if Colrex Compound stops working well.

Long-term use of Colrex Compound can lead to physical DEPENDENCE. The early sign of addiction is medicine ineffectiveness. Dependence is not an issue in terminal illness, when pain relief is more important. If using Colrex Compound for an extended period of time, do not suddenly stop taking Colrex Compound without your doctor"s approval. WITHDRAWAL symptoms have occurred when Colrex Compound is suddenly stopped and may include anxiety; diarrhea; fever; runny nose or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping use of Colrex Compound .

Possible side effects of Colrex Compound :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; flushing or redness of face; stomach pain; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; coma; confusion; deep sleep or loss of consciousness; difficulty breathing; diminished mental alertness; hallucinations; hot or cold skin; large and unchanging pupils; sedation; seizures; shaking; sleeplessness; slowed breathing; slow heartbeat.

Store Colrex Compound at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Colrex Compound out of the reach of children and away from pets.

General information:

• If you have any questions about Colrex Compound , please talk with your doctor, pharmacist, or other health care provider.
• Colrex Compound is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Colrex Compound . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.