Colestipol Granules

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Colestipol Granules


Generic Name: Colestipol Granules (koe-LES-ti-pol)
Brand Name: Colestid

Colestipol Granules is used for:

Lowering blood cholesterol levels. It is used along with changes in diet.

Colestipol Granules is a bile acid sequestrant/anion-exchange resin. It works by increasing the removal of bile acids from the body. As the body loses bile acids, it replaces them by converting cholesterol from the blood to bile acids. This causes the blood level of cholesterol to decrease.

Do NOT use Colestipol Granules if:

  • you are allergic to any ingredient in Colestipol Granules
  • you have an obstruction of your biliary tract, bile drainage problems, impacted feces, high blood chloride levels, or certain types of elevated blood lipid levels (type III, IV, or V hyperlipidemia)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Colestipol Granules:

Some medical conditions may interact with Colestipol Granules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart disease, constipation, a blood disease, high blood levels of triglycerides, a clotting disorder, poor absorption from the intestinal tract or other intestinal problems, kidney problems, or phenylketonuria (PKU)

Some MEDICINES MAY INTERACT with Colestipol Granules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol) or digitoxin because their effectiveness may be altered by Colestipol Granules
  • Chlorothiazide, furosemide, gemfibrozil, hydrochlorothiazide, oral hydrocortisone, oral phosphate supplements, penicillin, or tetracycline because their effectiveness may be decreased by Colestipol Granules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Colestipol Granules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Colestipol Granules:

Use Colestipol Granules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Colestipol Granules is taken by mouth, usually before or with meals.
  • Digoxin and Colestipol Granules should be taken as far apart as possible.
  • Corticosteroids (eg, hydrocortisone) and diuretics (eg, chlorothiazide, furosemide) should be taken 2 to 3 hours before this medicine.
  • All other medicines should be taken at least 1 hour before or 4 hours after taking Colestipol Granules.
  • Do not take Colestipol Granules in its dry form. Always mix with water or other fluids before taking.
  • If you are taking Colestipol Granules with a beverage, add the prescribed amount of medicine to 3 to 6 ounces of liquid before taking. Stir until well mixed (it will not dissolve) before drinking. After drinking all the liquid, rinse the glass with more liquid and drink it to ensure that all medicine is taken.
  • Colestipol Granules may also be taken with milk in hot or cold breakfast cereals, or mixed with soups (chicken noodle, tomato) or fruits (applesauce, peaches, crushed pineapple, pears, fruit cocktail) containing plenty of fluid.
  • Drink several full glasses of water or other liquid (8 oz/240 mL) daily, unless directed otherwise by your doctor.
  • If you miss a dose of Colestipol Granules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Colestipol Granules.

Important safety information:

  • Colestipol Granules may cause dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Colestipol Granules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • The color of the powder may vary from batch to batch. This is normal and does not change the effect.
  • Lab tests, including lipid profiles and prothrombin times, may be performed while you use Colestipol Granules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Colestipol Granules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Colestipol Granules while you are pregnant. It is not known if Colestipol Granules is found in breast milk. If you are or will be breast-feeding while you use Colestipol Granules, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Colestipol Granules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal pain; aggravated hemorrhoids; bloating; constipation; cramps; diarrhea; dizziness; drowsiness; gas; heartburn; indigestion; lightheadedness; loose stools; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); increased bleeding; severe constipation.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include constipation; feeling of fullness.

Proper storage of Colestipol Granules:

Store Colestipol Granules at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Colestipol Granules out of the reach of children and away from pets.

General information:

  • If you have any questions about Colestipol Granules, please talk with your doctor, pharmacist, or other health care provider.
  • Colestipol Granules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Colestipol Granules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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