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BENZOYL PEROXIDE (Topical)

Some commonly used brand names are:

In the U.S.—

Acne-Aid Vanishing Cream
Acne-Aid Aqua Gel
Ambi 10 Acne Medication
Benoxyl 5 Lotion
Benoxyl 10 Lotion
Benzac AC 21/2 Gel
Benzac AC 5 Gel
Benzac AC 10 Gel
Benzac AC Wash 21/2
Benzac AC Wash 5
Benzac AC Wash 10
Benzac 5 Gel
Benzac 10 Gel
Benzac W 21/2 Gel
Benzac W 5 Gel
Benzac W 10 Gel
Benzac W Wash 5
Benzac W Wash 10
5 Benzagel
10 Benzagel
BenzaShave 5 Cream
BenzaShave 10 Cream
Brevoxyl-4 Gel
Brevoxyl-8 Gel
Brevoxyl-4 Cleansing Lotion
Brevoxyl-8 Cleansing Lotion
Clean & Clear Persagel 5
Clean & Clear Persagel 10
Clearasil Maximum Strength Medicated Anti-Acne 10 Tinted Cream
Clearasil Maximum Strength Medicated Anti-Acne 10 Vanishing Cream
Clearasil Maximum Strength Medicated Anti-Acne 10 Vanishing Lotion
Clear By Design 2.5 Gel
Clearplex 5
Clearplex 10
Cuticura Acne 5 Cream
Del-Aqua-5 Gel
Del-Aqua-10 Gel
Desquam-E 2.5 Gel
Desquam-E 5 Gel
Desquam-E 10 Gel
Desquam-X 10 Bar
Desquam-X 2.5 Gel
Desquam-X 5 Gel
Desquam-X 10 Gel
Desquam-X 5 Wash
Desquam-X 10 Wash
Exact 5 Tinted Cream
Exact 5 Vanishing Cream
Fostex 10 Bar
Fostex 10 Cream
Fostex 5 Gel
Fostex 10 BPO Gel
Fostex 10 Wash
Loroxide 5.5 Lotion
Neutrogena Acne Mask 5
Noxzema Clear-ups Maximum Strength 10 Lotion
Noxzema Clear-ups On-The-Spot 10 Lotion
Oxy Balance Deep Action Night Formula Lotion
Oxy 10 Balance Emergency Spot Treatment Cover-Up Formula Gel
Oxy 10 Balance Emergency Spot Treatment Invisible Formula Gel
Oxy Balance Emergency Spot Treatment Invisible Formula Gel
Oxy 10 Balance Maximum Medicated Face Wash
PanOxyl AQ 21/2 Gel
PanOxyl AQ 5 Gel
PanOxyl AQ 10 Gel
PanOxyl 5 Bar
PanOxyl 10 Bar
PanOxyl 5 Gel
PanOxyl 10 Gel
Student"s Choice Acne Medication
Triaz
Triaz Cleanser

In Canada—

Acetoxyl 2.5 Gel
Acetoxyl 5 Gel
Acetoxyl 10 Gel
Acetoxyl 20 Gel
Acnomel B.P. 5 Lotion
Benoxyl 5 Lotion
Benoxyl 10 Lotion
Benoxyl 20 Lotion
Benzac AC 5 Gel
Benzac AC 10 Gel
Benzac W 5 Gel
Benzac W 10 Gel
Benzac W Wash 5
Benzac W Wash 10
2.5 Benzagel Acne Gel
5 Benzagel Acne Gel
10 Benzagel Acne Gel
2.5 Benzagel Acne Lotion
5 Benzagel Acne Lotion
5 Benzagel Acne Wash
5 Benzagel Liquid Acne Soap
Clearasil BP Plus 5 Lotion
Clearasil BP Plus Skin Tone Cream
Dermacne
Dermoxyl Aqua 5 Gel
Dermoxyl 5 Gel
Dermoxyl 10 Gel
Dermoxyl 20 Gel
Desquam-X 5 Gel
Desquam-X 10 Gel
Desquam-X 5 Wash
Desquam-X 10 Wash
H ₂ Oxyl 2.5 Gel
H ₂ Oxyl 5 Gel
H ₂ Oxyl 10 Gel
H ₂ Oxyl 20 Gel
Loroxide 5 Lotion
Oxyderm 5 Lotion
Oxyderm 10 Lotion
Oxyderm 20 Lotion
Oxy 5 Regular Strength Cover-Up Cream
Oxy 5 Regular Strength Vanishing Lotion
Oxy 5 Sensitive Skin Vanishing Lotion
PanOxyl Aquagel 2.5
PanOxyl Aquagel 5
PanOxyl Aquagel 10
PanOxyl Aquagel 20
PanOxyl 5 Bar
PanOxyl 10 Bar
PanOxyl 5 Gel
PanOxyl 10 Gel
PanOxyl 15 Gel
PanOxyl 20 Gel
PanOxyl 5 Wash
PanOxyl 10 Wash
Solugel 4
Solugel 8
Xerac BP 5

Generic name product may be available in the U.S.

Description

Benzoyl peroxide (BEN-zoe-ill per-OX-ide) is used to treat acne.

It may also be used for other conditions as determined by your doctor.

Some of these preparations are available only with your doctor"s prescription. Others are available without a prescription; however, your doctor may have special instructions on the proper use of benzoyl peroxide for your medical condition.

Benzoyl peroxide is available in the following dosage forms:

Topical
Cleansing bar (U.S. and Canada)
Cream (U.S. and Canada)
Gel (U.S. and Canada)
Lotion (U.S. and Canada)
Cleansing lotion (U.S. and Canada)
Facial mask (U.S.)
Stick

Before Using This Medicine

If you are using this medicine without a prescription, carefully read and follow any precautions on the label. For benzoyl peroxide, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to benzoyl peroxide. Also tell your health care professional if you are allergic to any other substances, such as preservatives or dyes.

Pregnancy—Studies on effects in pregnancy have not been done in either humans or animals. However, benzoyl peroxide may be absorbed through the skin.

Breast-feeding—Benzoyl peroxide may be absorbed through the mother"s skin. It is not known whether it passes into the breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Children—For children up to 12 years of age: Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of benzoyl peroxide with use in other age groups. For children 12 years of age and older: Although there is no specific information comparing use of benzoyl peroxide in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children 12 years of age and older than it does in adults.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of benzoyl peroxide in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin.

Other medical problems—The presence of other medical problems may affect the use of benzoyl peroxide. Make sure you tell your doctor if you have any other medical problems, especially:

Dermatitis, seborrheic or
Eczema or
Red or raw skin, including sunburned skin—Irritation will occur if benzoyl peroxide is used with these conditions

Proper Use of This Medicine

It is very important that you use this medicine only as directed . Do not use more of it and do not use it more often than recommended on the label, unless otherwise directed by your doctor. To do so may cause irritation of the skin.

Do not use this medicine in or around the eyes or lips, or inside the nose, or on sensitive areas of the neck . Spread the medicine away from these areas when applying. If the medicine gets on these areas, wash with water at once.

Do not apply this medicine to windburned or sunburned skin or on open wounds, unless otherwise directed by your doctor .

This medicine usually comes with patient directions. Read them carefully before using the medicine.

To use the cream, gel, lotion, or stick form of benzoyl peroxide:

Before applying, wash the affected area with nonmedicated soap and water or with a mild cleanser and then gently pat dry with a towel.
Apply enough medicine to cover the affected areas, and rub in gently.

To use the shave cream form of benzoyl peroxide:

Wet the area to be shaved.
Apply a small amount of the shave cream and gently rub over entire area.
Shave.
Rinse the area and pat dry.
After-shave lotions or other drying face products should not be used without checking with your doctor first.

To use the cleansing bar, cleansing lotion, or soap form of benzoyl peroxide:

Use to wash the affected areas as directed.

To use the facial mask form of benzoyl peroxide:

Before applying, wash the affected area with a nonmedicated cleanser. Then rinse and pat dry.
Using a circular motion, apply a thin layer of the mask evenly over the affected area.
Allow the mask to dry for 15 to 25 minutes.
Then rinse thoroughly with warm water and pat dry.

After applying the medicine, wash your hands to remove any medicine that might remain on them.

Dosing—The dose of benzoyl peroxide will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of benzoyl peroxide. If your dose is different, do not change it unless your doctor tells you to do so.

For acne:
- For cleansing bar dosage form:
  - Adults and children 12 years of age and over—Use two or three times a day, or as directed by your doctor.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.
- For cleansing lotion, cream , or gel dosage forms:
  - Adults and children 12 years of age and over—Use on the affected area(s) of the skin one or two times a day.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.
- For lotion dosage form:
  - Adults and children 12 years of age and over—Use on the affected area(s) of the skin one to four times a day.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.
- For facial mask dosage form:
  - Adults and children 12 years of age and over—Use one time a week or as directed by your doctor.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.
- For stick dosage form:
  - Adults and children 12 years of age and over—Use on the affected area(s) of the skin one to three times a day.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.

Missed dose—If you miss a dose of this medicine, apply or use it as soon as possible. Then go back to your regular dosing schedule.

Storage—To store this medicine:

Keep out of the reach of children.
Store away from heat and direct light.
Keep the cream, gel, or liquid form of this medicine from freezing.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

During the first 3 weeks you are using benzoyl peroxide, your skin may become irritated. Also, your acne may seem to get worse before it gets better. If your skin problem has not improved within 4 to 6 weeks, check with your health care professional.

You should not wash the areas of the skin treated with benzoyl peroxide for at least 1 hour after application.

Avoid using any other topical medicine on the same area within 1 hour before or after using benzoyl peroxide . Otherwise, benzoyl peroxide may not work properly.

Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as benzoyl peroxide:

Any other topical acne product or skin product containing a peeling agent (such as resorcinol, salicylic acid, sulfur, or tretinoin);
Hair products that are irritating, such as permanents or hair removal products;
Skin products that cause sensitivity to the sun, such as those containing lime or spices;
Skin products containing a large amount of alcohol, such as astringents, shaving creams, or after-shave lotions; or
Skin products that are too drying or abrasive, such as some cosmetics, soaps, or skin cleansers.

Using these products along with benzoyl peroxide may cause mild to severe irritation of the skin. Although skin irritation can occur, some doctors sometimes allow benzoyl peroxide to be used with tretinoin to treat acne. Usually tretinoin is applied at night so that it doesn"t cause a problem with any other topical products that you might use during the day. Check with your doctor before using any other topical medicines with benzoyl peroxide.

This medicine may bleach hair or colored fabrics .

Check with your doctor at any time your skin becomes too dry or irritated. Your health care professional can help you choose the right skin products for you to reduce skin dryness and irritation.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Painful irritation of skin, including burning, blistering, crusting, itching, severe redness, or swelling; skin rash

Symptoms of overdose

Burning, itching, scaling, redness, or swelling of skin (severe)

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your health care professional if any of the following side effects continue or are bothersome:

Less common

Dryness or peeling of skin (may occur after a few days); feeling of warmth, mild stinging, and redness of skin

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your health care professional.

Additional Information

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, benzoyl peroxide is used in certain patients with the following medical conditions:

Decubital ulcer (bed sores)
Stasis ulcer (a certain type of ulcer)

Other than the above information, there is no additional information relating to proper use, precautions, or side effects for these uses.

Revised: 07/29/1998

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

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