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|Chromic Phosphate P 32 |
Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9 Home Chromic Phosphate P 32Pronouncation: (KROME-ik FOSS-fate)Class: Radiopharmaceuticals Trade Names: Mechanism of ActionPharmacologyLocal irradiation by beta emission. Chromic phosphate P32 decays by beta emission with a physical half-life of 14.3 days. Indications and UsageAdultsTreatment of peritoneal or pleural effusions caused by metastatic disease, cancer. ContraindicationsPresence of ulcerative tumors; administration in exposed cavities or where there is evidence of loculation unless its extent is determined. Dosage and AdministrationTreatment of Peritoneal or Pleural Effusions Caused by Metastatic Disease, CancerAdults (about 70 kg) Intraperitoneal 10 to 20 mCi. Adults (about 70 kg)Intrapleural 6 to 12 mCi. Adults (about 70 kg)Interstitial 0.1 to 0.5 mCi/g of estimated weight of tumor. General Advice
Drug InteractionsNone well documented. Laboratory Test InteractionsNone well documented. Adverse ReactionsGINausea; abdominal cramping. MiscellaneousTransitory radiation sickness; bone marrow depression; pleuritis; peritonitis. PrecautionsPregnancyCategory C . LactationUse only when clearly needed. Benzyl alcoholThis product contains benzyl alcohol, which has been associated with fatal “gasping syndrome” in preterm infants. Intracavitary instillationCareful intracavitary instillation is required to avoid placing the dose of chromic phosphate P 32 into intrapleural or intraperitoneal loculations, bowel lumen, or the body wall. Intestinal fibrosis or necrosis and chronic fibrosis or the body wall have resulted from unrecognized misplacement of the therapeutic agent. Intracavitary useNot for intravascular use. Large tumor massesWhen other forms of treatment fail to control effusion, chromic phosphate P 32 may be used. Radioactive materialsEnsure minimum radiation exposure to the patient and occupational workers consistent with proper patient management. Patient Information
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