CellCept Solution

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CellCept Solution


Generic Name: Mycophenolate Mofetil Injection Solution (mye-koe-FEN-oh-late MOE-feh-til)
Brand Name: CellCept

CellCept Solution decreases your immune system, which may decrease your ability to fight illness or infection. It may also increase the risk of certain types of cancer (eg, lymphoma). Use CellCept Solution only under close medical supervision.


CellCept Solution is used for:

Preventing organ rejection following kidney, liver, or heart transplants. CellCept Solution is used in combination with other medicines. It may also be used to treat other conditions as determined by your doctor.

CellCept Solution is an immunosuppressant. It works by decreasing the activity of certain cells that make up part of the immune system to help reduce the risk of organ transplant rejection.

Do NOT use CellCept Solution if:

  • you are allergic to any ingredient in CellCept Solution
  • you are taking cholestyramine, colestipol, azathioprine, or mycophenolic acid

Contact your doctor or health care provider right away if any of these apply to you.

Before using CellCept Solution:

Some medical conditions may interact with CellCept Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach or intestinal problems, including ulcers; kidney problems; or a rare hereditary deficiency of hypoxanthine guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome
  • if you are scheduled for a vaccination

Some MEDICINES MAY INTERACT with CellCept Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cholestyramine or colestipol because the effectiveness of CellCept Solution may be decreased
  • Azathioprine, mycophenolic acid, acyclovir, ganciclovir, or probenecid because the actions and side effects of CellCept Solution may be increased
  • Oral contraceptives because their effectiveness may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if CellCept Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use CellCept Solution:

Use CellCept Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • CellCept Solution is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using CellCept Solution at home, carefully follow the injection procedures taught to you by your health care provider.
  • If CellCept Solution contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Do not inhale or touch the medicine. If the medicine touches your skin or eyes, wash skin thoroughly with soap and water or rinse eyes with water.
  • Your doctor may change this prescription to medicine you take by mouth. If this occurs, be sure you understand the dosing schedule and follow it exactly.
  • If you miss a dose of CellCept Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use CellCept Solution.

Important safety information:

  • CellCept Solution may cause blurred vision, drowsiness, or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to CellCept Solution. Using CellCept Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • CellCept Solution may increase your risk of developing certain types of cancer (eg, lymphoma, skin cancer). Avoid sunlamps or tanning booths. Limit sun exposure by using a sunscreen or protective clothing if you must be outside for a prolonged period.
  • CellCept Solution may lower your body"s ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection including fever, sore throat, rashes, or chills.
  • Check with your doctor before having vaccinations while you are taking CellCept Solution.
  • While you are using CellCept Solution, it is important to brush and floss your teeth carefully and also have regular dental check-ups.
  • Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.
  • LAB TESTS, including complete blood cell counts, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Do not use CellCept Solution if you are pregnant. You must have a negative pregnancy test within 1 week before starting CellCept Solution. To prevent pregnancy, use 2 effective forms of birth control before therapy, during therapy, and for 6 weeks after therapy is completed. The effectiveness of birth control pills may be decreased when taken with CellCept Solution. Talk with your doctor or pharmacist to determine which forms of effective birth control are right for you. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if CellCept Solution is excreted in breast milk. Do not breast-feed while taking CellCept Solution.

Possible side effects of CellCept Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; anxiety; back pain; constipation; cough; diarrhea; dizziness; headache; incoordination; increased hair growth; indigestion; loss of appetite; mild or moderate stomach pain; muscle cramps; muscle or joint pain; nausea; pain; pain in arms or legs; pain, redness, or swelling at the injection site; shakiness; sleeplessness; stomach bloating; vomiting; weakness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; bloody or black stools; changes in heart rhythm; chest pain; enlarged lymph nodes; enlarged stomach; fainting; fever; frequent or infrequent urination; itching; leg pain; night sweats; pounding in the chest; severe vomiting or stomach pain; skin growths; sore throat; swelling of the hands, ankles, or feet; swollen glands; unusual bruising or bleeding; unusual lumps or growths; unusual tiredness; upper respiratory tract infection; urinary tract infection; vomiting blood that looks like coffee grounds; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include diarrhea; nausea; vomiting.

Proper storage of CellCept Solution:

Store CellCept Solution at room temperature, 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep CellCept Solution, as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about CellCept Solution, please talk with your doctor, pharmacist, or other health care provider.
  • CellCept Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about CellCept Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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