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|Carbinoxamine/Hydrocodone/Phenylephrine Liquid

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Carbinoxamine/Hydrocodone/Phenylephrine Liquid

Generic Name: Carbinoxamine/Hydrocodone/Phenylephrine Liquid (car-bihn-OCKS-ah-meen/hye-droe-KOE-done/fen-il-EF-rin)
Brand Name: Examples include Excof-SF and Max HC

Carbinoxamine/Hydrocodone/Phenylephrine Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory tract infections, and allergies. It may also be used for other conditions as determined by your doctor.

Carbinoxamine/Hydrocodone/Phenylephrine Liquid is a decongestant, antihistamine, and narcotic cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Carbinoxamine/Hydrocodone/Phenylephrine Liquid if:

you are allergic to any ingredient in Carbinoxamine/Hydrocodone/Phenylephrine Liquid or any other codeine- or morphine-related medicine (eg, oxycodone)
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
you are unable to urinate or are having an asthma attack
you have diarrhea due to antibiotic use or poisoning
you are taking sodium oxybate (GHB), droxidopa, or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Carbinoxamine/Hydrocodone/Phenylephrine Liquid:

Some medical conditions may interact with Carbinoxamine/Hydrocodone/Phenylephrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat or other heart or blood vessel problems
if you have a history of adrenal gland problems (eg, adrenal gland tumor); liver or kidney problems; high blood pressure; diabetes; stroke; glaucoma; increased pressure in the eye; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; trouble sleeping; an enlarged prostate or other prostate problems; or thyroid problems
if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
if you have a history of head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures
if you have a history of stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel, chronic constipation), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery
if you are very ill or very weak or you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Carbinoxamine/Hydrocodone/Phenylephrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Carbinoxamine/Hydrocodone/Phenylephrine Liquid"s side effects
Barbiturates (eg, phenobarbital), cimetidine, digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased
Naltrexone because it may decrease Carbinoxamine/Hydrocodone/Phenylephrine Liquid"s effectiveness
Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Carbinoxamine/Hydrocodone/Phenylephrine Liquid
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Carbinoxamine/Hydrocodone/Phenylephrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if this medicine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Carbinoxamine/Hydrocodone/Phenylephrine Liquid:

Use Carbinoxamine/Hydrocodone/Phenylephrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Carbinoxamine/Hydrocodone/Phenylephrine Liquid by mouth with or without food.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Carbinoxamine/Hydrocodone/Phenylephrine Liquid and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carbinoxamine/Hydrocodone/Phenylephrine Liquid.

Important safety information:

Carbinoxamine/Hydrocodone/Phenylephrine Liquid may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Carbinoxamine/Hydrocodone/Phenylephrine Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Carbinoxamine/Hydrocodone/Phenylephrine Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Do not use Carbinoxamine/Hydrocodone/Phenylephrine Liquid for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
Do not take diet or appetite control medicines while you are taking Carbinoxamine/Hydrocodone/Phenylephrine Liquid without checking with your doctor.
Carbinoxamine/Hydrocodone/Phenylephrine Liquid has phenylephrine in it. Before you start any new medicine, check the label to see if it has phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
Carbinoxamine/Hydrocodone/Phenylephrine Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Carbinoxamine/Hydrocodone/Phenylephrine Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Carbinoxamine/Hydrocodone/Phenylephrine Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Carbinoxamine/Hydrocodone/Phenylephrine Liquid for a few days before the tests.
Tell your doctor or dentist that you take Carbinoxamine/Hydrocodone/Phenylephrine Liquid before you receive any medical or dental care, emergency care, or surgery.
Use Carbinoxamine/Hydrocodone/Phenylephrine Liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness or excitability.
Caution is advised when using Carbinoxamine/Hydrocodone/Phenylephrine Liquid in CHILDREN; they may be more sensitive to its effects, especially drowsiness or excitability.
Carbinoxamine/Hydrocodone/Phenylephrine Liquid should not be used in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Carbinoxamine/Hydrocodone/Phenylephrine Liquid may cause harm to the fetus if taken during late pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Carbinoxamine/Hydrocodone/Phenylephrine Liquid while you are pregnant. It is not known if Carbinoxamine/Hydrocodone/Phenylephrine Liquid is found in breast milk. Do not breast-feed while taking Carbinoxamine/Hydrocodone/Phenylephrine Liquid.

When used for long periods of time or at high doses, Carbinoxamine/Hydrocodone/Phenylephrine Liquid may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Carbinoxamine/Hydrocodone/Phenylephrine Liquid stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Carbinoxamine/Hydrocodone/Phenylephrine Liquid. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Carbinoxamine/Hydrocodone/Phenylephrine Liquid, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Carbinoxamine/Hydrocodone/Phenylephrine Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth; excitability; headache; loss of appetite; nausea; nervousness or anxiety; restlessness; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include cold, clammy skin; confusion; difficulty breathing; dilated pupils; flushing; hallucinations; loss of coordination; overexcitement; seizures; severe dizziness, lightheadedness, headache, or vomiting; severe drowsiness; unusually fast, slow, or irregular heartbeat.

Proper storage of Carbinoxamine/Hydrocodone/Phenylephrine Liquid:

Store Carbinoxamine/Hydrocodone/Phenylephrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carbinoxamine/Hydrocodone/Phenylephrine Liquid out of the reach of children and away from pets.

General information:

If you have any questions about Carbinoxamine/Hydrocodone/Phenylephrine Liquid, please talk with your doctor, pharmacist, or other health care provider.
Carbinoxamine/Hydrocodone/Phenylephrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Carbinoxamine/Hydrocodone/Phenylephrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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