Calan SR Controlled-Release Tablets

|Calan SR Controlled-Release Tablets

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Calan SR Controlled-Release Tablets

Generic Name: Verapamil Controlled-Release Tablets (ver-AP-a-mil)
Brand Name: Calan SR and Isoptin SR

Calan SR Controlled-Release Tablets is used for:

Treating high blood pressure. It may be used alone or other medicines. It may also be used for other conditions as determined by your doctor.

Calan SR Controlled-Release Tablets is a calcium channel blocker. It works by relaxing (dilating) your blood vessels, lowering blood pressure.

Do NOT use Calan SR Controlled-Release Tablets if:

  • you are allergic to any ingredient in Calan SR Controlled-Release Tablets
  • you have certain heart problems (eg, left-ventricular dysfunction, sick sinus syndrome, second- or third-degree heart block and do not have a pacemaker), very low blood pressure, or moderate to severe congestive heart failure
  • you have atrial fibrillation or flutter and a pre-excitation syndromes (extra conduction pathway in the heart), such as Wolff-Parkinson-White syndrome (WPW) or Lown-Ganong-Levine syndrome (LGL)
  • you have shock due to serious heart problems
  • you are taking dofetilide, eletriptan, erythromycin, or disopyramide

Contact your doctor or health care provider right away if any of these apply to you.

Before using Calan SR Controlled-Release Tablets:

Some medical conditions may interact with Calan SR Controlled-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart failure or a recent heart attack with lung congestion; low blood pressure; heart problems, including a very slow heart rate or heart valve disease
  • if you have kidney or liver disease, muscular dystrophy, or neurologic disease
  • if you are taking another blood pressure medicine

Some MEDICINES MAY INTERACT with Calan SR Controlled-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), ketolides (eg, telithromycin), lincomycin, and macrolides (eg, erythromycin) because the actions and side effects of Calan SR Controlled-Release Tablets, some potentially life-threatening, may be increased
  • Rifampin or St. John"s wort because they may decrease Calan SR Controlled-Release Tablets"s effectiveness
  • Aldosterone blockers (eg, spironolactone), beta-blockers (eg, propranolol), carbamazepine, digoxin, disopyramide, dofetilide, eletriptan, erythromycin, flecainide, general anesthetics, HMG-CoA reductase inhibitors (eg, simvastatin), lithium, nondepolarizing muscle relaxants (eg, atracurium), quinazolines (eg, metolazone), quinidine, or theophyllines (eg, aminophylline) because the actions and side effects, some potentially life-threatening, may be increased by Calan SR Controlled-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Calan SR Controlled-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Calan SR Controlled-Release Tablets:

Use Calan SR Controlled-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Calan SR Controlled-Release Tablets by mouth with or without food.
  • Do not eat grapefruit or drink grapefruit juice while you use Calan SR Controlled-Release Tablets.
  • Swallow Calan SR Controlled-Release Tablets whole. Do not crush or chew before swallowing.
  • Taking Calan SR Controlled-Release Tablets at the same time each day will help you remember to take it.
  • If you miss a dose of Calan SR Controlled-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Calan SR Controlled-Release Tablets.

Important safety information:

  • Calan SR Controlled-Release Tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Calan SR Controlled-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Calan SR Controlled-Release Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Calan SR Controlled-Release Tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Tell your doctor or dentist that you take Calan SR Controlled-Release Tablets before you receive any medical or dental care, emergency care, or surgery.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Lab tests, including liver function, kidney function, complete blood cell count, and blood pressure, may be performed while you use Calan SR Controlled-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Calan SR Controlled-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Calan SR Controlled-Release Tablets should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Calan SR Controlled-Release Tablets while you are pregnant. Calan SR Controlled-Release Tablets is found in breast milk. Do not breast-feed while taking Calan SR Controlled-Release Tablets.

Possible side effects of Calan SR Controlled-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; fatigue; general feeling of being unwell; headache; lightheadedness; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; fever; lightheadedness, especially upon standing; severe dizziness; shortness of breath; swelling of feet or hands; unusually fast, slow, or irregular heartbeat; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include decreased mental status; dizziness; loss of consciousness; seizures; shortness of breath; slow or irregular heartbeat.

Proper storage of Calan SR Controlled-Release Tablets:

Store Calan SR Controlled-Release Tablets between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Calan SR Controlled-Release Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Calan SR Controlled-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Calan SR Controlled-Release Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Calan SR Controlled-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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