Butorphanol Solution

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|Butorphanol Solution

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Butorphanol Solution


Generic Name: Butorphanol Nasal Solution (byoo-TOR-fan-ahl)
Brand Name: Generic only. No brands available.

Butorphanol Solution is used for:

Relieving headache or pain due to surgery, labor, or other causes. It may also be used to treat other conditions as determined by your doctor.

Butorphanol Solution is a narcotic analgesic. It works by blocking certain nerve stimulation that causes pain.

Do NOT use Butorphanol Solution if:

  • you are allergic to any ingredient in Butorphanol Solution
  • you are taking sodium oxybate (gamma hydroxybutyrate; GHB) or you drink alcohol
  • you have diarrhea due to poisoning, difficulty breathing, or pseudomembranous colitis
  • you are dependent on narcotic pain relievers

Contact your doctor or health care provider right away if any of these apply to you.

Before using Butorphanol Solution:

Some medical conditions may interact with Butorphanol Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have stomach problems; prostate problems; asthma or other breathing problems; heart problems; recent heart attack, surgery, or trauma; liver disease; high blood pressure; underactive thyroid; increased pressure on the brain or a brain lesion; thoughts of suicide; seizures; bowel problems; or urinary problems
  • if you have a history of substance abuse or dependence

Some MEDICINES MAY INTERACT with Butorphanol Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Naltrexone or rifampin because the effectiveness of Butorphanol Solution may be decreased
  • Barbiturate anesthetics (eg, thiopental), cimetidine, ethanol, ketorolac, or sodium oxybate (GHB) because side effects, such as difficulty breathing or seizures, may occur
  • Barbiturate anesthetics (eg, thiopental) or sodium oxybate (GHB) because the actions and side effects of these medicines may be increased
  • Methadone or mexiletine because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Butorphanol Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Butorphanol Solution:

Use Butorphanol Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Butorphanol Solution is supplied as a nasal pump. Your pharmacist may have assembled the pump for you.
  • Butorphanol Solution comes with an instruction sheet that explains how to use it. Read and make sure you understand the instructions before using a dose.
  • The usual dose of Butorphanol Solution is one spray into one nostril. Do not spray into both nostrils unless directed by your doctor.
  • If you miss a dose of Butorphanol Solution and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Butorphanol Solution.

Important safety information:

  • Butorphanol Solution may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Butorphanol Solution. Using Butorphanol Solution alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Avoid drinking alcohol while you are using Butorphanol Solution.
  • Before you have any medical or dental surgery or emergency treatment, tell your doctor or dentist that you are taking Butorphanol Solution.
  • Do not take more of Butorphanol Solution or take it more often than recommended by your doctor. Exceeding the recommended dose or taking Butorphanol Solution for longer than prescribed may be habit forming.
  • Caution should be used in the ELDERLY since they may be more sensitive to the effects of Butorphanol Solution.
  • Butorphanol Solution is not recommended for use in CHILDREN. Safety and effectiveness have not been established.
  • PREGNANCY and BREAST-FEEDING: If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Butorphanol Solution during pregnancy. It is unknown if Butorphanol Solution is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the benefits and risks to your baby.

Butorphanol Solution may be habit-forming and lead to DEPENDENCE if used in high doses or for a long period of time. If you are on long-term or high dosage therapy, you may have WITHDRAWAL symptoms (eg, convulsions, tremor, stomach and muscle cramps, vomiting, sweating) if you suddenly stop taking Butorphanol Solution. Do not stop therapy abruptly or change dosage without asking your pharmacist or doctor. Discuss overuse with your doctor or pharmacist.

Possible side effects of Butorphanol Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; dizziness; drowsiness; dry mouth; lightheadedness; nasal irritation; nasal stuffiness; nausea; runny nose; sleeplessness; sore throat; stuffy nose; unpleasant taste.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; blurred vision; chest pain; confusion; cough; ear pain; excessive confusion; excessive drowsiness; fainting; flushing; rash or hives; restlessness; ringing in the ears; seizures; slow or difficult breathing; slow or irregular heartbeat; tremors; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include cold and clammy skin; deep sleep; dizziness; drowsiness; lightheadedness; loss of consciousness; slowed breathing; and slowed heartbeat.

Proper storage of Butorphanol Solution:

Store Butorphanol Solution at room temperature between 59 and 77 degrees F (15 and 25 degrees C), away from heat and light. Do not store in the bathroom. Keep Butorphanol Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Butorphanol Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Butorphanol Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Butorphanol Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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