Budesonide Suspension

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Budesonide Suspension


Generic Name: Budesonide Inhalation Suspension (byoo-DESS-oh-nide)
Brand Name: Pulmicort Respules

Use caution if you switch from an oral steroid (eg, prednisone) to Budesonide Suspension. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again.

Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.


Budesonide Suspension is used for:

Long-term treatment of asthma and prevention of asthma in children 1 to 8 years of age. It is not used to relieve an asthma attack. It may also be used for other conditions as determined by your doctor.

Budesonide Suspension is an inhaled corticosteroid. It works by decreasing the irritation and swelling of the breathing tubes (bronchioles) of the lung to control or prevent asthma symptoms.

Do NOT use Budesonide Suspension if:

  • you are allergic to any ingredient in Budesonide Suspension
  • you are having an asthma attack
  • you are taking mifepristone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Budesonide Suspension:

Some medical conditions may interact with Budesonide Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have glaucoma; cataracts; a herpes eye infection; a bacterial, fungal, parasitic, or viral infection; diarrhea; measles; tuberculosis; chicken pox; or shingles
  • if you have had a positive TB skin test or have recently been vaccinated

Some MEDICINES MAY INTERACT with Budesonide Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease Budesonide Suspension"s effectiveness
  • Clarithromycin, steroidal contraceptives (eg, birth control pills), or imidazole antifungals (eg, ketoconazole, itraconazole) because they may increase the risk of Budesonide Suspension"s side effects
  • Ritodrine or live vaccines because the risk of their side effects may be increased by Budesonide Suspension
  • Hydantoins (eg, phenytoin) because their effectiveness may be decreased by Budesonide Suspension
  • Mifepristone because risk of side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Budesonide Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Budesonide Suspension:

Use Budesonide Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Do not mix Budesonide Suspension with other medicines in the nebulizer.
  • Budesonide Suspension is to be used in a nebulizer or a respirator. Do not use Budesonide Suspension in an ultrasonic nebulizer.
  • Open the aluminum foil envelope and remove 1 ampule. Record the date on which you open the foil on the back of the envelope. Once the foil is open, the unused ampules should be used within 2 weeks.
  • Gently shake the ampules, and then squeeze the contents into the nebulizer. Connect the nebulizer to the air pump and begin treatment as directed. Breathe calmly and evenly. When there is no more mist in the nebulizer chamber, the treatment is complete.
  • Rinse the mouth with water (without swallowing) after each treatment to help prevent mouth infections. Make sure to wash the face after using a face mask. Rinse well and dry.
  • Once an ampule is opened, use the medicine immediately or discard.
  • Improvement may be seen within 2 to 8 days after beginning treatment, although the full benefit may not been seen for 4 to 6 weeks after starting treatment. If the asthma symptoms do not improve in 4 to 6 weeks, contact your health care provider.
  • After use, wash the reservoir of the nebulizer, mouthpiece, and mask according to the manufacturer"s directions.
  • If you miss a dose of Budesonide Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Budesonide Suspension.

Important safety information:

  • It may take several days for Budesonide Suspension to work. Do not stop using Budesonide Suspension without checking with your doctor.
  • Budesonide Suspension will not stop an asthma attack. Always carry appropriate medicine (eg, bronchodilator inhaler) in case you have an asthma attack. Contact your doctor immediately if your bronchodilator does not help you to breathe normally.
  • Tell your doctor or dentist that you take Budesonide Suspension before you receive any medical or dental care, emergency care, or surgery.
  • Carry an ID card at all times that says you take Budesonide Suspension.
  • Use caution if you switch from an oral steroid (eg, prednisone) to Budesonide Suspension. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
  • If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Budesonide Suspension. Talk with your doctor before you receive any vaccine.
  • Lab tests, including adrenal function assessment, may be performed while you use Budesonide Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Budesonide Suspension.
  • Budesonide Suspension should not be used in CHILDREN younger than 12 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Budesonide Suspension while you are pregnant. It is unknown if Budesonide Suspension is found in breast milk. If you are or will be breast-feeding while you use Budesonide Suspension, check with your doctor. Discuss any possible risks to your baby.

If symptoms of WITHDRAWAL occur when switching from an oral medicine to an inhaled one (muscle and joint pain, exhaustion, depression), contact your health care provider at once.

Possible side effects of Budesonide Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Coughing; diarrhea; nosebleed; rash; redness of the eyes; runny nose; stomach pain; stomach problems; throat irritation; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); depression; ear infection; fainting; increased wheezing; infection (fever, chills, sore throat); irritability; mental/mood changes; personality change; severe dizziness; sinus infection; sudden weight loss; tightness in the lungs; unusual weakness; vomiting; white patches in the mouth or throat.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Budesonide Suspension:

Store Budesonide Suspension at controlled room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and direct sunlight. Replace the cover after each use. Do not puncture, break, or burn the canister even if it appears to be empty. Do not store in the bathroom. Keep Budesonide Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Budesonide Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Budesonide Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Budesonide Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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