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Generic Name: Balsalazide (bal-SAL-a-zide)
Brand Name: Colazal

Balsalazide is used for:

Treating mildly to moderately active inflammation of the colon. It may also be used for other conditions as determined by your doctor.

Balsalazide is an anti-inflammatory. How it works is not fully known. It appears to reduce ulcerative colitis (inflammation of the colon) by preventing the production of substances that cause the inflammation.

Do NOT use Balsalazide if:

  • you are allergic to any ingredient in Balsalazide , nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, naproxen), or any medicine containing a salicylate (eg, aspirin)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Balsalazide :

Tell your health care provider if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney disease or intestinal blockage

Some MEDICINES MAY INTERACT with Balsalazide . Tell your health care provider if you are taking any of the following medicines:

  • Meglitinide antidiabetics (eg, repaglinide), sulfonylureas (eg, glipizide), or valproic acid because the risk of their side effects may be increased by Balsalazide
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), probenecid, or sulfinpyrazone because their effectiveness may be decreased by Balsalazide

This may not be a complete list of all interactions that may occur. Ask your health care provider if Balsalazide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Balsalazide :

Use Balsalazide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Balsalazide by mouth with or without food.
  • If you cannot swallow the capsule whole, you may open it and sprinkle the contents over a spoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. You may crush or chew the medicine before swallowing if necessary. Do not store the mixture for future use.
  • If you miss a dose of Balsalazide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Balsalazide .

Important safety information:

  • Balsalazide may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Balsalazide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Balsalazide should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Balsalazide while you are pregnant. It is not known if Balsalazide is found in breast milk. If you are or will be breast-feeding while you use Balsalazide , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Balsalazide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Coughing; diarrhea; headache; heartburn; joint or muscle pain; loss of appetite; runny or stuffy nose; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; fatigue; fever; nausea; rectal bleeding; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately.

Proper storage of Balsalazide :

Store Balsalazide at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Balsalazide out of the reach of children and away from pets.

General information:

  • If you have any questions about Balsalazide , please talk with your doctor, pharmacist, or other health care provider.
  • Balsalazide is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Balsalazide . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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