Aspirin, Sodium Bicarbonate, And Citric Acid

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ASPIRIN, SODIUM BICARBONATE, AND CITRIC ACID (Systemic)

Some commonly used brand names are:

In the U.S.—

  • Alka-Seltzer Effervescent Pain Reliever and Antacid
  • Flavored Alka-Seltzer Effervescent Pain Reliever and Antacid

In Canada—

  • Alka-Seltzer Effervescent Pain Reliever and Antacid
  • Flavored Alka-Seltzer Effervescent Pain Reliever and Antacid

Other commonly used names for aspirin are acetylsalicylic acid and ASA . Because Aspirin is a brand name in Canada, ASA is the term that commonly appears on Canadian product labels.

Category

  • Analgesic-antacid
  • Platelet aggregation inhibitor

Description

Aspirin, sodium bicarbonate, and citric acid (AS-pir-in, SOE-dee-um bye-KAR-boe-nate, and SI-trik AS-id) combination is used to relieve pain occurring together with heartburn, sour stomach, or acid indigestion.

The aspirin in this combination is the pain reliever. Aspirin belongs to the group of medicines known as salicylates (sa-LISS-ih-lates) and to the group of medicines known as anti-inflammatory analgesics. The sodium bicarbonate in this medicine is an antacid. It neutralizes stomach acid by combining with it to form a new substance that is not an acid.

Aspirin, sodium bicarbonate, and citric acid combination may also be used to lessen the chance of heart attack, stroke, or other problems that may occur when a blood vessel is blocked by blood clots. The aspirin in this medicine helps prevent dangerous blood clots from forming. However, this effect of aspirin may increase the chance of serious bleeding in some people. Therefore, aspirin should be used for this purpose only when your doctor decides, after studying your medical condition and history, that the danger of blood clots is greater than the risk of bleeding. Do not take aspirin to prevent blood clots or a heart attack unless it has been ordered by your doctor .

This combination medicine is available without a prescription. However, your doctor may have special instructions on the proper dose for your medical condition.

Aspirin, sodium bicarbonate, and citric acid combination is available in the following dosage form:

  • Oral
  • Effervescent tablets (U.S. and Canada)

Before Using This Medicine

If you are taking this medicine without a prescription, carefully read and follow any precautions on the label. For aspirin, sodium bicarbonate, and citric acid combination, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to aspirin or other salicylates, including methyl salicylate (oil of wintergreen), or to any of the following medicines:

  • Diclofenac (e.g., Voltaren)
  • Diflunisal (e.g., Dolobid)
  • Etodolac (e.g., Lodine)
  • Fenoprofen (e.g., Nalfon)
  • Floctafenine (e.g., Idarac)
  • Flurbiprofen, oral (e.g., Ansaid)
  • Ibuprofen (e.g., Motrin)
  • Indomethacin (e.g., Indocin)
  • Ketoprofen (e.g., Orudis)
  • Ketorolac (e.g., Toradol)
  • Meclofenamate (e.g., Meclomen)
  • Mefenamic acid (e.g., Ponstel)
  • Nabumetone (e.g., Relafen)
  • Naproxen (e.g., Naprosyn)
  • Oxaprozin (e.g., Daypro)
  • Oxyphenbutazone (e.g., Tandearil)
  • Phenylbutazone (e.g., Butazolidin)
  • Piroxicam (e.g., Feldene)
  • Sulindac (e.g., Clinoril)
  • Suprofen (e.g., Suprol)
  • Tenoxicam (e.g., Mobiflex)
  • Tiaprofenic acid (e.g., Surgam)
  • Tolmetin (e.g., Tolectin)
  • Zomepirac (e.g., Zomax)

Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Studies in humans have not shown that aspirin causes birth defects in humans. However, it has been shown to cause birth defects in animal studies.

Do not take aspirin during the last 3 months of pregnancy unless it has been ordered by your doctor . Some reports have suggested that too much use of aspirin late in pregnancy may cause a decrease in the newborn"s weight and possible death of the fetus or newborn infant. However, the mothers in these reports had been taking much larger amounts of aspirin than are usually recommended. Studies of mothers taking aspirin in the doses that are usually recommended did not show these unwanted effects. However, there is a chance that regular use of aspirin late in pregnancy may cause unwanted effects on the heart or blood flow in the fetus or in the newborn infant.

Use of aspirin during the last 2 weeks of pregnancy may cause bleeding problems in the fetus before or during delivery or in the newborn infant. Also, too much use of aspirin during the last 3 months of pregnancy may increase the length of pregnancy, prolong labor, cause other problems during delivery, or cause severe bleeding in the mother before, during, or after delivery.

The sodium in this combination medicine can cause your body to hold water. This may result in swelling and weight gain. Therefore, you should not use this combination medicine if you tend to hold body water.

Breast-feeding—Aspirin passes into the breast milk. However, aspirin (in the amounts used to relieve pain or prevent blood clots), sodium bicarbonate, and citric acid have not been reported to cause problems in nursing babies.

Children—Do not give any medicine containing aspirin to a child with fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child"s doctor . This is very important because aspirin may cause a serious illness called Reye"s syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the chance of side effects during treatment.

Older adults—People 60 years of age and older are especially sensitive to the effects of aspirin. This may increase the chance of side effects during treatment. Also, the sodium in this combination medicine can be harmful to some elderly people, especially if large amounts of the medicine are taken regularly. Therefore, it is best that older people not use this medicine for more than 5 days in a row, unless otherwise directed by their doctor.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this combination medicine, it is especially important that your health care professional know if you are taking any of the following:

  • Anticoagulants (blood thinners) or
  • Carbenicillin by injection (e.g., Geopen) or
  • Cefamandole (e.g., Mandol) or
  • Cefoperazone (e.g., Cefobid) or
  • Cefotetan (e.g., Cefotan) or
  • Dipyridamole (e.g., Persantine) or
  • Divalproex (e.g., Depakote) or
  • Heparin or
  • Pentoxifylline (e.g., Trental) or
  • Plicamycin (e.g., Mithracin) or
  • Ticarcillin (e.g., Ticar) or
  • Valproic acid (e.g., Depakene)—Use of these medicines together with aspirin may increase the chance of bleeding
  • Antidiabetics, oral (diabetes medicine you take by mouth)—Aspirin may increase the effects of these medicines; a change in dose may be needed
  • Ciprofloxacin (e.g., Cipro) or
  • Enoxacin (e.g., Penetrex) or
  • Itraconazole (e.g., Sporanox) or
  • Ketoconazole (e.g., Nizoral) or
  • Lomefloxacin (e.g., Maxaquin) or
  • Methenamine (e.g., Mandelamine) or
  • Norfloxacin (e.g., Noroxin) or
  • Ofloxacin (e.g., Floxin) or
  • Tetracyclines (medicine for infection), taken by mouth—Sodium bicarbonate can keep these medicines from working properly
  • Mecamylamine (e.g., Inversine)—Sodium bicarbonate may increase the chance of unwanted effects by causing mecamylamine to stay in your body longer than usual
  • Medicine for pain and/or inflammation (except narcotics) or
  • Methotrexate (e.g., Mexate) or
  • Vancomycin (e.g., Vancocin)—The chance of serious side effects may be increased
  • Probenecid (e.g., Benemid) or
  • Sulfinpyrazone (e.g., Anturane)—Aspirin can keep these medicines from working properly when they are used to treat gout

Other medical problems—The presence of other medical problems may affect the use of this combination medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anemia or
  • Stomach ulcer or other stomach problems—Aspirin can make these conditions worse
  • Appendicitis (symptoms of, such as stomach or lower abdominal pain, cramping, bloating, soreness, nausea, or vomiting)—Sodium bicarbonate can make your condition worse; also, people who may have appendicitis need medical attention and should not try to treat themselves
  • Asthma, allergies, and nasal polyps (history of) or
  • Kidney disease or
  • Liver disease—The chance of serious side effects may be increased
  • Edema (swelling of face, fingers, feet, or lower legs caused by too much water in the body) or
  • Heart disease or
  • High blood pressure or
  • Toxemia of pregnancy—The sodium in this combination medicine can make these conditions worse
  • Gout—Aspirin can make this condition worse and can also keep some medicines used to treat gout from working properly
  • Hemophilia or other bleeding problems—Aspirin increases the chance of serious bleeding

Proper Use of This Medicine

Make certain your health care professional knows if you are on any special diet, such as a low-sodium or low-sugar diet. This medicine contains a large amount of sodium (more than 500 mg in each tablet).

Unless otherwise directed by your doctor, do not take more of this medicine than is recommended on the package label . If too much is taken, serious side effects may occur.

Do not take this medicine if it has a strong vinegar-like odor . This odor means the aspirin in it is breaking down. If you have any questions about this, check with your health care professional.

To use this medicine:

  • The tablets must be dissolved in water before taking. Do not swallow the tablets or any pieces of the tablets.
  • Place the number of tablets needed for one dose (1 or 2 tablets) into a glass. Then add 1/2 glass (4 ounces) of cool water.
  • Check to be sure that the tablets have disappeared completely. This shows that all of the medicine is in the liquid. Then drink all of the liquid. You may drink the liquid while it is still fizzing or after the fizzing stops.
  • Add a little more water to the glass and drink that, to make sure that you get the full amount of the medicine.

Dosing—The dose of this combination medicine will be different for different people. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of this combination medicine. If your dose is different, do not change it unless your doctor tells you to do so.

  • For oral dosage forms (effervescent tablets):
    • For pain and upset stomach:
      • Adults and teenagers—One or two regular-strength (325-milligram [mg]) tablets every four to six hours as needed, one extra-strength (500-mg) tablet every four to six hours as needed, or two extra-strength (500-mg) tablets every six hours as needed, dissolved in water. Elderly people should not take more than four regular-strength or extra-strength tablets a day. Other adults and teenagers should not take more than 6 regular-strength flavored tablets, 8 regular-strength unflavored tablets, or 7 extra-strength tablets a day.
      • Children—The dose depends on the child"s age.
        • Children younger than 3 years of age: Use and dose must be determined by your doctor.
        • Children 3 to 5 years of age: One-half of a regular-strength (325-mg) tablet, dissolved in water, every four to six hours as needed.
        • Children 6 to 12 years of age: One regular-strength (325-mg) tablet, dissolved in water, every four to six hours as needed.
    • For reducing the chance of heart attack, stroke, or other problems that may occur when a blood vessel is blocked by blood clots:
      • Adults—One regular-strength (325-mg) tablet a day, dissolved in water.
      • Children and teenagers—Use and dose must be determined by your doctor.

Missed dose—If your doctor has ordered you to take this medicine according to a regular schedule and you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—To store this medicine:

  • Keep out of the reach of children. Overdose is very dangerous in young children.
  • Store away from heat and direct light.
  • Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

If you will be taking this medicine for a long time (more than 5 days in a row for children or 10 days in a row for adults), your doctor should check your progress at regular visits.

Check with your doctor if your pain and/or upset stomach last for more than 10 days for adults or 5 days for children or if they get worse, if new symptoms occur, or if the painful area is red or swollen. These could be signs of a serious condition that needs medical treatment.

The sodium bicarbonate in this combination medicine can keep other medicines from working properly if the 2 medicines are taken too close together. Always take this medicine :

  • At least 6 hours before or 2 hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin (e.g., Maxaquin) .
  • At least 8 hours before or 2 hours after taking enoxacin (e.g., Penetrex) .
  • At least 2 hours after taking itraconazole (e.g., Sporanox) .
  • At least 3 hours before or after taking ketoconazole (e.g., Nizoral) .
  • At least 2 hours before or after taking norfloxacin (e.g., Noroxin) or ofloxacin (e.g., Floxin) .
  • At least 3 or 4 hours before or after taking a tetracycline antibiotic by mouth .
  • At least 1 or 2 hours before or after taking any other medicine by mouth .

If you are also taking a laxative that contains cellulose, take this combination medicine at least 2 hours before or after you take the laxative. Taking the medicines too close together may lessen the effects of aspirin.

Check the labels of all nonprescription (over-the-counter [OTC]) and prescription medicines you now take . If any contain aspirin or other salicylates, including bismuth subsalicylate (e.g., Pepto-Bismol), magnesium salicylate (e.g., Nuprin Backache Caplets), or salsalate (e.g., Disalcid); if any contain salicylic acid (present in some shampoos or medicines for your skin); or if any contain sodium, check with your health care professional . Taking other salicylate-containing or other sodium-containing products together with this medicine may cause an overdose.

Do not take aspirin for 5 days before any surgery, including dental surgery, unless otherwise directed by your medical doctor or dentist. Taking aspirin during this time may cause bleeding problems.

For patients taking this medicine to lessen the chance of a heart attack, stroke, or other problems caused by blood clots:

  • Take only the amount of aspirin ordered by your doctor . If you need a medicine to relieve pain, a fever, or arthritis, your doctor may not want you to take extra aspirin. It is a good idea to discuss this with your doctor, so that you will know ahead of time what medicine to take.
  • Do not stop taking this medicine for any reason without first checking with the doctor who directed you to take it .

Taking certain other medicines together with a salicylate may increase the chance of unwanted effects. The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. If your doctor directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take any of the following medicines together with a salicylate for more than a few days, unless your doctor has directed you to do so and is following your progress :

  • Acetaminophen (e.g., Tylenol)
  • Diclofenac (e.g., Voltaren)
  • Diflunisal (e.g., Dolobid)
  • Etodolac (e.g., Lodine)
  • Fenoprofen (e.g., Nalfon)
  • Floctafenine (e.g., Idarac)
  • Flurbiprofen, oral (e.g., Ansaid)
  • Ibuprofen (e.g., Motrin)
  • Indomethacin (e.g., Indocin)
  • Ketoprofen (e.g., Orudis)
  • Ketorolac (e.g., Toradol)
  • Meclofenamate (e.g., Meclomen)
  • Mefenamic acid (e.g., Ponstel)
  • Nabumetone (e.g., Relafen)
  • Naproxen (e.g., Naprosyn)
  • Oxaprozin (e.g., Daypro)
  • Phenylbutazone (e.g., Butazolidin)
  • Piroxicam (e.g., Feldene)
  • Sulindac (e.g., Clinoril)
  • Tenoxicam (e.g., Mobiflex)
  • Tiaprofenic acid (e.g., Surgam)
  • Tolmetin (e.g., Tolectin)

If you will be taking more than an occasional 1 or 2 doses of this medicine:

  • Do not drink alcoholic beverages . Drinking alcoholic beverages while you are taking aspirin, especially if you take aspirin regularly or in large amounts, may increase the chance of stomach problems.
  • Do not drink a lot of milk or eat a lot of milk products . To do so may increase the chance of side effects.
  • To prevent side effects caused by too much sodium in the body, you may need to limit the amount of sodium in the foods you eat. Some foods that contain large amounts of sodium are canned soup, canned vegetables, pickles, ketchup, green and ripe (black) olives, relish, frankfurters and other sausage-type meats, soy sauce, and carbonated beverages. If you have any questions about this, check with your health care professional.

Before you have any medical tests, tell the person in charge that you are taking this medicine. The results of some tests may be affected by the aspirin in this combination medicine.

For diabetic patients :

  • Aspirin can cause false urine glucose (sugar) test results if you regularly take 8 or more 324-mg, or 4 or more 500-mg (extra-strength), tablets a day. Smaller amounts or occasional use of aspirin usually will not affect the test results. However, check with your health care professional if you notice any change in your urine glucose test results. This is especially important if your diabetes is not well-controlled.

If you think that you or anyone else may have taken an overdose, get emergency help at once . Taking an overdose of aspirin may cause unconsciousness or death, especially in young children. Signs of overdose include convulsions (seizures), hearing loss, confusion, ringing or buzzing in the ears, severe drowsiness or tiredness, severe excitement or nervousness, and fast or deep breathing.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if:

  • too much medicine is taken.
  • the medicine is taken several times a day.
  • the medicine is taken for more than a few days in a row.

Get emergency help immediately if any of the following side effects occur:

Any loss of hearing; bloody urine; confusion; convulsions (seizures); diarrhea (severe or continuing); difficulty in swallowing; dizziness, lightheadedness, or feeling faint (severe); drowsiness (severe); excitement or nervousness (severe); fast or deep breathing; flushing, redness, or other change in skin color; hallucinations (seeing, hearing, or feeling things that are not there); nausea or vomiting (severe or continuing); shortness of breath, troubled breathing, tightness in chest, or wheezing; stomach pain (severe or continuing); swelling of eyelids, face, or lips; unexplained fever; uncontrollable flapping movements of the hands (especially in elderly patients); vision problems

Signs of overdose in children

Changes in behavior; drowsiness or tiredness (severe); fast or deep breathing

Also, check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Bloody or black, tarry stools; frequent urge to urinate; headache (severe or continuing); increased blood pressure; loss of appetite (continuing); mood or mental changes; muscle pain or twitching; ringing or buzzing in ears (continuing); skin rash, hives, or itching; slow breathing; swelling of face, fingers, ankles, feet, or lower legs; unpleasant taste; unusual tiredness or weakness; vomiting of blood or material that looks like coffee grounds; weight gain (unusual)

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your health care professional if any of the following side effects continue or are bothersome:

Heartburn or indigestion; increased thirst; nausea or vomiting; stomach pain (mild)

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Revised: 08/29/1994

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ci6ric acid, aspirin, sodium bicarbonate, and ci5ric acid, aspirin, sodium bicarbonate, and citeic acid, aspirin, sodium bicarbonate, and citdic acid, aspirin, sodium bicarbonate, and citfic acid, aspirin, sodium bicarbonate, and cittic acid, aspirin, sodium bicarbonate, and cit5ic acid, aspirin, sodium bicarbonate, and cit4ic acid, aspirin, sodium bicarbonate, and citruc acid, aspirin, sodium bicarbonate, and citrjc acid, aspirin, sodium bicarbonate, and citrkc acid, aspirin, sodium bicarbonate, and citroc acid, aspirin, sodium bicarbonate, and citr9c acid, aspirin, sodium bicarbonate, and citr8c acid, aspirin, sodium bicarbonate, and citrix acid, aspirin, sodium bicarbonate, and citriv acid, aspirin, sodium bicarbonate, and citrif acid, aspirin, sodium bicarbonate, and citrid acid, aspirin, sodium bicarbonate, and citric zcid, aspirin, sodium bicarbonate, and citric scid, aspirin, sodium bicarbonate, and citric wcid, aspirin, sodium bicarbonate, and citric qcid, aspirin, sodium bicarbonate, and citric axid, aspirin, sodium bicarbonate, and citric avid, aspirin, sodium bicarbonate, and citric afid, aspirin, sodium bicarbonate, and citric adid, aspirin, sodium bicarbonate, and citric acud, aspirin, sodium bicarbonate, and citric acjd, aspirin, sodium bicarbonate, and citric ackd, aspirin, sodium bicarbonate, and citric acod, aspirin, sodium bicarbonate, and citric ac9d, aspirin, sodium bicarbonate, and citric ac8d, aspirin, sodium bicarbonate, and citric acis, aspirin, sodium bicarbonate, and citric acix, aspirin, sodium bicarbonate, and citric acic, aspirin, sodium bicarbonate, and citric acif, aspirin, sodium bicarbonate, and citric acir, aspirin, sodium bicarbonate, and citric acie, spirin, sodium bicarbonate, and citric acid, apirin, sodium bicarbonate, and citric acid, asirin, sodium bicarbonate, and citric acid, asprin, sodium bicarbonate, and citric acid, aspiin, sodium bicarbonate, and citric acid, aspirn, sodium bicarbonate, and citric acid, aspiri, sodium bicarbonate, and citric acid, aspirin sodium bicarbonate, and citric acid, aspirin,sodium bicarbonate, and citric acid, aspirin, odium bicarbonate, and citric acid, aspirin, sdium bicarbonate, and citric acid, aspirin, soium bicarbonate, and citric acid, aspirin, sodum bicarbonate, and citric acid, aspirin, sodim bicarbonate, and citric acid, aspirin, sodiu bicarbonate, and citric acid, aspirin, sodiumbicarbonate, and citric acid, aspirin, sodium icarbonate, and citric acid, aspirin, sodium bcarbonate, and citric acid, aspirin, sodium biarbonate, and citric acid, aspirin, sodium bicrbonate, and citric acid, aspirin, sodium bicabonate, and citric acid, aspirin, sodium bicaronate, and citric acid, aspirin, sodium bicarbnate, and citric acid, aspirin, sodium bicarboate, and citric acid, aspirin, sodium bicarbonte, and citric acid, aspirin, sodium bicarbonae, and citric acid, aspirin, sodium bicarbonat, and citric acid, aspirin, sodium bicarbonate and citric acid, aspirin, sodium bicarbonate,and citric acid, aspirin, sodium bicarbonate, nd citric acid, aspirin, sodium bicarbonate, ad citric acid, aspirin, sodium bicarbonate, an citric acid, aspirin, sodium bicarbonate, andcitric acid, aspirin, sodium bicarbonate, and itric acid, aspirin, sodium bicarbonate, and ctric acid, aspirin, sodium bicarbonate, and ciric acid, aspirin, sodium bicarbonate, and citic acid, aspirin, sodium bicarbonate, and citrc acid, aspirin, sodium bicarbonate, and citri acid, aspirin, sodium bicarbonate, and citricacid, aspirin, sodium bicarbonate, and citric cid, aspirin, sodium bicarbonate, and citric aid, aspirin, sodium bicarbonate, and citric acd, aspirin, sodium bicarbonate, and citric aci, sapirin, sodium bicarbonate, and citric acid, apsirin, sodium bicarbonate, and citric acid, asiprin, sodium bicarbonate, and citric acid, aspriin, sodium bicarbonate, and citric acid, aspiirn, sodium bicarbonate, and citric acid, aspirni, sodium bicarbonate, and citric acid, aspiri,n sodium bicarbonate, and citric acid, aspirin ,sodium bicarbonate, and citric acid, aspirin,s odium bicarbonate, and citric acid, aspirin, osdium bicarbonate, and citric acid, aspirin, sdoium bicarbonate, and citric acid, aspirin, soidum bicarbonate, and citric acid, aspirin, soduim bicarbonate, and citric acid, aspirin, sodimu bicarbonate, and citric acid, aspirin, sodiu mbicarbonate, and citric acid, aspirin, sodiumb icarbonate, and citric acid, aspirin, sodium ibcarbonate, and citric acid, aspirin, sodium bciarbonate, and citric acid, aspirin, sodium biacrbonate, and citric acid, aspirin, sodium bicrabonate, and citric acid, aspirin, sodium bicabronate, and citric acid, aspirin, sodium bicarobnate, and citric acid, aspirin, sodium bicarbnoate, and citric acid, aspirin, sodium bicarboante, and citric acid, aspirin, sodium bicarbontae, and citric acid, aspirin, sodium bicarbonaet, and citric acid, aspirin, sodium bicarbonat,e and citric acid, aspirin, sodium bicarbonate ,and citric acid, aspirin, sodium bicarbonate,a nd citric acid, aspirin, sodium bicarbonate, nad citric acid, aspirin, sodium bicarbonate, adn citric acid, aspirin, sodium bicarbonate, an dcitric acid, aspirin, sodium bicarbonate, andc itric acid, aspirin, sodium bicarbonate, and ictric acid, aspirin, sodium bicarbonate, and ctiric acid, aspirin, sodium bicarbonate, and cirtic acid, aspirin, sodium bicarbonate, and citirc acid, aspirin, sodium bicarbonate, and citrci acid, aspirin, sodium bicarbonate, and citri cacid, aspirin, sodium bicarbonate, and citrica cid, aspirin, sodium bicarbonate, and citric caid, aspirin, sodium bicarbonate, and citric aicd, aspirin, sodium bicarbonate, and citric acdi, aaspirin, sodium bicarbonate, and citric acid, asspirin, sodium bicarbonate, and citric acid, asppirin, sodium bicarbonate, and citric acid, aspiirin, sodium bicarbonate, and citric acid, aspirrin, sodium bicarbonate, and citric acid, aspiriin, sodium bicarbonate, and citric acid, aspirinn, sodium bicarbonate, and citric acid, aspirin,, sodium bicarbonate, and citric acid, aspirin, sodium bicarbonate, and citric acid, aspirin, ssodium bicarbonate, and citric acid, aspirin, soodium bicarbonate, and citric acid, aspirin, soddium bicarbonate, and citric acid, aspirin, sodiium bicarbonate, and citric acid, aspirin, sodiuum bicarbonate, and citric acid, aspirin, sodiumm bicarbonate, and citric acid, aspirin, sodium bicarbonate, and citric acid, aspirin, sodium bbicarbonate, and citric acid, aspirin, sodium biicarbonate, and citric acid, aspirin, sodium biccarbonate, and citric acid, aspirin, sodium bicaarbonate, and citric acid, aspirin, sodium bicarrbonate, and citric acid, aspirin, sodium bicarbbonate, and citric acid, aspirin, sodium bicarboonate, and citric acid, aspirin, sodium bicarbonnate, and citric acid, aspirin, sodium bicarbonaate, and citric acid, aspirin, sodium bicarbonatte, and citric acid, aspirin, sodium bicarbonatee, and citric acid, aspirin, sodium bicarbonate,, and citric acid, aspirin, sodium bicarbonate, and citric acid, aspirin, sodium bicarbonate, aand citric acid, aspirin, sodium bicarbonate, annd citric acid, aspirin, sodium bicarbonate, andd citric acid, aspirin, sodium bicarbonate, and citric acid, aspirin, sodium bicarbonate, and ccitric acid, aspirin, sodium bicarbonate, and ciitric acid, aspirin, sodium bicarbonate, and cittric acid, aspirin, sodium bicarbonate, and citrric acid, aspirin, sodium bicarbonate, and citriic acid, aspirin, sodium bicarbonate, and citricc acid, aspirin, sodium bicarbonate, and citric acid, aspirin, sodium bicarbonate, and citric aacid, aspirin, sodium bicarbonate, and citric accid, aspirin, sodium bicarbonate, and citric aciid, aspirin, sodium bicarbonate, and citric acidd, etc.



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