drug-information.ru |
|Alcohol and Dextrose |
Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9 Home Alcohol and DextroseGeneric Name: Alcohol and Dextrose monohydrate Dosage Form: Injection, usp Alcohol and Dextrose DescriptionEach 100 mL of 5% Alcohol and 5% Dextrose Injection USP contains: pH: 5.0 (3.5–6.5); Calories per liter: 450 Each 100 mL of 10% Alcohol and 5% Dextrose Injection USP contains: Alcohol USP 10 mL; Hydrous Dextrose USP 5 g pH: 4.6 (3.5–6.5); Calories per liter: 720 These intravenous solutions are sterile, nonpyrogenic, hypertonic and contain no bacteriostatic or antimicrobial agents. The formulas of the active ingredients are:
Alcohol and Dextrose - Clinical PharmacologyAlcohol and Dextrose Injections USP are an intravenous source of calories. In the average adult, pure ethyl alcohol is metabolized at a rate of 10 to 20 mL per hour. Sedative effects of alcohol occur if the rate of infusion exceeds the rate of metabolism. Dextrose (D-glucose) can be infused at a maximum rate of approximately 0.5 to 0.85 g/kg of body weight/hr without producing significant glycosuria. Thus, the maximum rate that alcohol can be infused without producing sedative effects is well below the maximum rate of utilization of dextrose. Alcohol is metabolized, mostly in the liver, to acetaldehyde or acetate. The rate of oxidation is a linear function of time. Starvation lowers the rate of metabolism and insulin increases the rate. Indications and Usage for Alcohol and DextroseAlcohol and Dextrose Injections USP are indicated for increasing caloric intake. ContraindicationsAlcohol should not be used in patients with epilepsy, urinary tract infection, or diabetic coma. Alcohol is contraindicated in patients who have been addicted to it. Do not give subcutaneously and avoid extravasation during intravenous administration. Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products. WarningsAlcohol should be used cautiously, if at all, in patients with liver impairment, in the presence of shock, following cranial surgery, in actual or anticipated postpartum hemorrhage, or in the presence of significant renal impairment. Alcohol decreases blood sugar in diabetic patients. In the untreated diabetic, the rate of alcohol metabolism is slowed. As a nutrient, alcohol supplies only calories. Given alone, it may cause or potentiate vitamin deficiencies and certain liver alterations. Alcohol crosses the placenta rapidly and enters the fetal circulation. It may also be found in the milk of lactating women. The use of these solutions in pregnancy should be carefully considered. PrecautionsGeneralAlcohol and Dextrose Injections USP should be administered slowly, and the patient observed for restlessness or narcosis. The half lives of phenytoin, warfarin and tolbutamide may be shortened 50% to 75% by concurrent administration of alcohol. Alcohol increases serum uric acid and can precipitate acute gout. The vasodilating effect of alcohol may potentiate postural hypotension, particularly in association with some antihypertensive drugs. If the administration is controlled by a pumping device, care must be taken to discontinue pumping action before the container runs dry or air embolism may result. To minimize the risk of possible incompatibilities arising from mixing this solution with other additives that may be prescribed, the final infusate should be inspected for cloudiness or precipitation immediately after mixing, prior to administration, and periodically during administration. Use only if solution is clear and vacuum is present. Usage in PregnancyPregnancy Category CAnimal reproduction studies have not been conducted with Alcohol and Dextrose Injections USP. It is also not known whether Alcohol and Dextrose Injections USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Alcohol and Dextrose Injections USP should be given to a pregnant woman only if clearly needed. Pediatric UseSafety and effectiveness in children have not been established. Adverse ReactionsAlcoholic intoxication may occur with too rapid infusion. Vertigo, flushing, disorientation (especially in elderly patients), or sedation may also occur. An alcoholic odor may be noted in the breath. Generally, these effects can be avoided by slowing the rate of infusion. Too rapid infusion of hypertonic solutions may cause local pain and, rarely, vein irritation. Use of the largest available peripheral vein and a well-placed, small bore needle is recommended. OverdosageIn the event of fluid overload during parenteral therapy, reevaluate the patient"s condition, and institute appropriate corrective treatment. Alcohol and Dextrose Dosage and AdministrationAlcohol and Dextrose Injections USP are administered by intravenous infusion only. Total dosage and rate of infusion depend on the patient"s response and tolerance. The average adult can metabolize approximately 10 mL of pure alcohol per hour, equivalent to the alcohol contained in 200 mL of a 5% solution or 100 mL of a 10% solution. The usual adult dosage is 1 to 2 liters and rarely exceeds 3 liters of a 5% solution in a 24-hour period. Children may be given 40 mL per kg per 24 hours or from 350 mL to 1000 mL depending on size and clinical response. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. How is Alcohol and Dextrose SuppliedThese solutions are supplied sterile and nonpyrogenic in single dose glass containers packaged 6 per case.
Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product. Rx only Revised: June 1999 Directions for Use of B. Braun Glass ContainersBefore use, perform the following checks:
B. Braun Medical Inc. In Canada, distributed by: ©1999 B. Braun Medical Inc. Y36-002-423
Revised: 10/2006 Where can I get more information about Alcohol and Dextrose ? We recommend to use www.Drugs.com Typical mistypes for Alcohol and Dextrose zlcohol and dextrose, slcohol and dextrose, wlcohol and dextrose, qlcohol and dextrose, akcohol and dextrose, apcohol and dextrose, aocohol and dextrose, alxohol and dextrose, alvohol and dextrose, alfohol and dextrose, aldohol and dextrose, alcihol and dextrose, alckhol and dextrose, alclhol and dextrose, alcphol and dextrose, alc0hol and dextrose, alc9hol and dextrose, alcogol and dextrose, alcobol and dextrose, alconol and dextrose, alcojol and dextrose, alcouol and dextrose, alcoyol and dextrose, alcohil and dextrose, alcohkl and dextrose, alcohll and dextrose, alcohpl and dextrose, alcoh0l and dextrose, alcoh9l and dextrose, alcohok and dextrose, alcohop and dextrose, alcohoo and dextrose, alcohol znd dextrose, alcohol snd dextrose, alcohol wnd dextrose, alcohol qnd dextrose, alcohol abd dextrose, alcohol amd dextrose, alcohol ajd dextrose, alcohol ahd dextrose, alcohol ans dextrose, alcohol anx dextrose, alcohol anc dextrose, alcohol anf dextrose, alcohol anr dextrose, alcohol ane dextrose, alcohol and sextrose, alcohol and xextrose, alcohol and cextrose, alcohol and fextrose, alcohol and rextrose, alcohol and eextrose, alcohol and dwxtrose, alcohol and dsxtrose, alcohol and ddxtrose, alcohol and drxtrose, alcohol and d4xtrose, alcohol and d3xtrose, alcohol and deztrose, alcohol and dectrose, alcohol and dedtrose, alcohol and destrose, alcohol and dexrrose, alcohol and dexfrose, alcohol and dexgrose, alcohol and dexyrose, alcohol and dex6rose, alcohol and dex5rose, alcohol and dexteose, alcohol and dextdose, alcohol and dextfose, alcohol and dexttose, alcohol and dext5ose, alcohol and dext4ose, alcohol and dextrise, alcohol and dextrkse, alcohol and dextrlse, alcohol and dextrpse, alcohol and dextr0se, alcohol and dextr9se, alcohol and dextroae, alcohol and dextroze, alcohol and dextroxe, alcohol and dextrode, alcohol and dextroee, alcohol and dextrowe, alcohol and dextrosw, alcohol and dextross, alcohol and dextrosd, alcohol and dextrosr, alcohol and dextros4, alcohol and dextros3, lcohol and dextrose, acohol and dextrose, alohol and dextrose, alchol and dextrose, alcool and dextrose, alcohl and dextrose, alcoho and dextrose, alcoholand dextrose, alcohol nd dextrose, alcohol ad dextrose, alcohol an dextrose, alcohol anddextrose, alcohol and extrose, alcohol and dxtrose, alcohol and detrose, alcohol and dexrose, alcohol and dextose, alcohol and dextrse, alcohol and dextroe, alcohol and dextros, lacohol and dextrose, aclohol and dextrose, alochol and dextrose, alchool and dextrose, alcoohl and dextrose, alcohlo and dextrose, alcoho land dextrose, alcohola nd dextrose, alcohol nad dextrose, alcohol adn dextrose, alcohol an ddextrose, alcohol andd extrose, alcohol and edxtrose, alcohol and dxetrose, alcohol and detxrose, alcohol and dexrtose, alcohol and dextorse, alcohol and dextrsoe, alcohol and dextroes, aalcohol and dextrose, allcohol and dextrose, alccohol and dextrose, alcoohol and dextrose, alcohhol and dextrose, alcohool and dextrose, alcoholl and dextrose, alcohol and dextrose, alcohol aand dextrose, alcohol annd dextrose, alcohol andd dextrose, alcohol and dextrose, alcohol and ddextrose, alcohol and deextrose, alcohol and dexxtrose, alcohol and dexttrose, alcohol and dextrrose, alcohol and dextroose, alcohol and dextrosse, alcohol and dextrosee, etc.
|