Acetazolamide Solution

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|Acetazolamide Solution

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Acetazolamide Solution


Generic Name: Acetazolamide Injection Solution (a-set-a-ZOLE-a-mide)
Brand Name: Generic only. No brands available.

Acetazolamide Solution is used for:

Treating certain types of glaucoma, epilepsy, or edema (fluid buildup) in combination with other medicines. It may also be used to treat other conditions as determined by your doctor.

Acetazolamide Solution is a carbonic anhydrase inhibitor. It reduces fluid pressure in the eyeball by decreasing fluid formation in the eyeball. It also increases the removal of water from the body by the kidney. It also may block certain nerve discharges that may contribute to seizures.

Do NOT use Acetazolamide Solution if:

  • you are allergic to any ingredient in Acetazolamide Solution
  • you have adrenal gland problems, low blood levels of potassium or sodium, kidney problems, liver problems (eg, cirrhosis), high blood levels of chloride, or other electrolyte problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Acetazolamide Solution:

Some medical conditions may interact with Acetazolamide Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney stones, a lung disease, glaucoma (eg, chronic non-congestive angle-closure glaucoma), diabetes, or difficulty breathing
  • if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide

Some MEDICINES MAY INTERACT with Acetazolamide Solution. Tell your health care provider if you are taking any of the following medicines:

  • Salicylates (eg, aspirin) because the risk of toxic side effects of Acetazolamide Solution may be increased
  • Other carbonic anhydrase inhibitors (eg, methazolamide), cyclosporine, quinidine, phenytoin, amphetamine, or sodium bicarbonate because the actions and side effects of these medicines may be increased
  • Primidone, salicylates (eg, aspirin), lithium, or methenamine because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetazolamide Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Acetazolamide Solution:

Use Acetazolamide Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Acetazolamide Solution is usually administered as an intravenous injection at your doctor"s office, hospital, or clinic.
  • If you are using Acetazolamide Solution at home, carefully follow the injection procedures taught to you by your health care provider.
  • If the medicine contains particles or is discolored, or if the vial/container is cracked or damaged in any way, do not use it.
  • Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Acetazolamide Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Acetazolamide Solution.

Important safety information:

  • Acetazolamide Solution may cause drowsiness or temporary vision changes. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Acetazolamide Solution. Using Acetazolamide Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Acetazolamide Solution may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Acetazolamide Solution. Use sunscreen or protective clothing if you must be outside for a prolonged period.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell your doctor or dentist that you are using Acetazolamide Solution.
  • Diabetes patients - Acetazolamide Solution may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • Acetazolamide Solution may interfere with certain lab tests. Make sure your doctor and laboratory personnel know you are taking Acetazolamide Solution.
  • LAB TESTS, including blood electrolyte levels, complete blood cell count, or platelet levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Acetazolamide Solution with caution in the ELDERLY because they may be more sensitive to its effects.
  • Use Acetazolamide Solution with extreme caution in CHILDREN; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Acetazolamide Solution during pregnancy. It is unknown if Acetazolamide Solution is excreted in breast milk. Do not breast-feed while taking Acetazolamide Solution.

Possible side effects of Acetazolamide Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; changes in taste; constipation; diarrhea; drowsiness; frequent urination; loss of appetite; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; changes in hearing; convulsions; dark, bloody stools; dark urine; fast breathing; fever; lack of energy; lower back pain; pain, redness, or swelling at the injection site; red, swollen, or blistered skin; ringing in the ears; sore throat; tingling of the arms or legs; unusual bleeding or bruising; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include abnormal skin sensations (eg, tingling, tickling, itching, burning); buzzing, ringing, or whistling in the ears; drowsiness; loss of appetite; loss of coordination; nausea; tremors; unsteady movements; vomiting.

Proper storage of Acetazolamide Solution:

Store the unmixed medicine at room temperature between 59 and 86 degrees F (15 and 30 degrees C). Store the mixed medicine in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Use Acetazolamide Solution within 12 hours of mixing. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetazolamide Solution, as well as syringes and needles, out of the reach of children and away from pets.

General information:

  • If you have any questions about Acetazolamide Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Acetazolamide Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Acetazolamide Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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