Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid

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Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid


Generic Name: Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid (a-seet-a-MIN-oh-fen/dex-troe-meth-OR-fan/dox-IL-a-meen/sue-do-eh-FED-rin)
Brand Name: Examples include NyQuil and Tylenol NightTime Cold & Flu

Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid is used for:

Relieving symptoms of pain, sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid is a decongestant, antihistamine, cough suppressant, and analgesic combination. It works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The analgesic and cough suppressant work in the brain to decrease pain and to reduce dry or unproductive cough.

Do NOT use Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid if:

  • you are allergic to any ingredient in Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are unable to urinate or are having an asthma attack
  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid:

Some medical conditions may interact with Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; an overactive thyroid; liver problems; or if you consume more than 3 alcohol-containing drinks per day
  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, isoniazid, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may be increased
  • Anticoagulants (eg, warfarin), digoxin, or droxidopa because risk of bleeding, irregular heartbeat or heart attack may be increased
  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid:

Use Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may be taken with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid.

Important safety information:

  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid. Using Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not take diet or appetite control medicines while you are taking Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid without checking with your doctor.
  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid contains acetaminophen and pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains acetaminophen or pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may cause liver damage. If you consume 3 or more alcohol-containing drinks every day, ask your doctor if you should take Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid or other pain relievers/fever reducers. Alcohol use combined with Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid may increase your risk for liver damage.
  • If you are scheduled for allergy skin testing, do not take Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid for several days before the test because it may decrease your response to the skin tests.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid.
  • Use Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid with caution in the ELDERLY because they may be more sensitive to its effects.
  • Caution is advised when using Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid in CHILDREN because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid, discuss with your doctor the benefits and risks of using Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid during pregnancy. It is unknown if Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid is excreted in breast milk. Do not breast-feed while taking Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid.

Possible side effects of Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; stomach pain; tremor; trouble sleeping; vision changes; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; and vomiting.

Proper storage of Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid:

Store Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Acetaminophen/Dextromethorphan/Doxylamine/Pseudoephedrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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