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Ultracet, |acetaminophen and tramadol Acetaminophen Aspirin Codeine

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acetaminophen and tramadol

Generic Name: acetaminophen and tramadol (a seet a MIN o fen and TRAM a dol)
Brand Names: Ultracet

What is acetaminophen and tramadol?

Tramadol is a narcotic-like pain reliever.

Acetaminophen is a less potent pain reliever that increases the effects of tramadol.

The combination of acetaminophen and tramadol is used to treat moderate to severe pain.

Acetaminophen and tramadol may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about acetaminophen and tramadol?

Do not take more of this medication than is recommended. An acetaminophen and tramadol overdose can be fatal. The maximum amount of acetaminophen and tramadol is 2 tablets per dose, or 8 tablets per day. Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen is contained in many cold and pain medicines available over the counter. If you take certain products together you may accidentally take too much acetaminophen. Read the label of any other medicine you are using to see if it contains acetaminophen.

Tell your doctor if you drink more than three alcoholic beverages per day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.

Seizures (convulsions) have occurred in some people taking acetaminophen and tramadol. You may be more likely to have a seizure while taking acetaminophen and tramadol if you have a history of seizures or head injury, a metabolic disorder, a brain or spinal cord infection, or if you are taking certain medicines. Talk with your doctor about your individual risk of having a seizure from this medicine.

While you are taking acetaminophen and tramadol, do not drink alcohol or use drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety). These drugs may slow your breathing or increase drowsiness when used together with acetaminophen and tramadol. Acetaminophen and tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my healthcare provider before taking acetaminophen and tramadol?

Do not take this medication if you are allergic to acetaminophen and tramadol, if you are intoxicated (drunk), or if you have recently used any of the following drugs:

alcohol;
narcotic pain medicine;
sedatives or tranquilizers (such as Valium);
medicine for depression or anxiety;
medicine for mental illness (such as bipolar disorder, schizophrenia); or
street drugs.

Seizures have occurred in some people taking acetaminophen and tramadol. Your risk of a seizure may be higher if you have any of these conditions:

a history of drug or alcohol addiction;
a history of epilepsy or other seizure disorder;
a history of head injury;
a metabolic disorder;
an infection of your brain or spinal cord, such as meningitis or encephalitis;
if you are also taking an antidepressant, mood stabilizer, or another narcotic pain medicine; or
if you have taken an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Talk with your doctor about your individual risk of having a seizure from this medicine.

Before taking acetaminophen and tramadol, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease;
asthma or other breathing disorder;
a stomach disorder; or
a history of depression, mental illness, or suicide attempt.

If you have any of these conditions, you may not be able to use acetaminophen and tramadol, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Acetaminophen and tramadol may also cause serious or fatal side effects in a newborn if the mother uses the medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Acetaminophen and tramadol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 16 years of age.

How should I take acetaminophen and tramadol?

Take acetaminophen and tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Acetaminophen and tramadol can be taken with or without food, but take it the same way each time.

Do not stop using this medication suddenly without talking to your doctor. You may need to gradually reduce the dose. Withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems may occur when you stop using acetaminophen and tramadol.

Call your doctor at once if you have any of these withdrawal symptoms after you stop using acetaminophen and tramadol.

Store acetaminophen and tramadol at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. A acetaminophen and tramadol overdose can be fatal.

Symptoms of a acetaminophen and tramadol overdose may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes, feeling light-headed, fainting, or coma.

What should I avoid while taking acetaminophen and tramadol?

Do not drink alcohol while you are taking acetaminophen and tramadol. Alcohol may cause a dangerous decrease in your breathing when used together with acetaminophen and tramadol.

Avoid using drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety). These drugs may slow your breathing or increase drowsiness when used together with acetaminophen and tramadol.

Acetaminophen and tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen is contained in many cold and pain medicines available over the counter. If you take certain products together you may accidentally take too much acetaminophen. Read the label of any other medicine you are using to see if it contains acetaminophen.

Acetaminophen and tramadol side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using acetaminophen and tramadol and call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
a red, blistering, peeling skin rash; or
shallow breathing, weak pulse.

Continue taking acetaminophen and tramadol and talk to your doctor if you have any of these less serious side effects:

dizziness, drowsiness, weakness;
nausea, vomiting, constipation, loss of appetite;
blurred vision;
flushing (redness, warmth, or tingly feeling); or
sleep problems (insomnia).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect acetaminophen and tramadol?

Before taking acetaminophen and tramadol, tell your doctor if you also use:

carbamazepine (Tegretol);
warfarin (Coumadin);
digoxin (Lanoxin, Lanoxicaps);
ketoconazole (Nizoral);
erythromycin (E-Mycin, E.E.S., Ery-Tab);
rifampin (Rifadin, Rimactane, Rifater);
St. John"s wort;
quinidine (Quinaglute, Quinadex, Cardioquin, Quinora); or
an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor); paroxetine (Paxil), or sertraline (Zoloft).

If you are using any of these drugs, you may not be able to use acetaminophen and tramadol or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect acetaminophen and tramadol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about acetaminophen and tramadol written for health professionals that you may read.

What does my medication look like?

Acetaminophen and acetaminophen and tramadol is available with a prescription under the brand name Ultracet. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Ultracet 325 mg/37.5 mg--yellow, capsule-shaped, film-coated tablets.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.06. Revision Date: 05/01/2007 9:15:40 AM.

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