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Generic Name: Acebutolol (a-see-BYOO-toe-lol)
Brand Name: Sectral

Acebutolol is used for:

Treating high blood pressure. It may be used alone or in combination with other medicines. It is used to treat certain kinds of irregular heartbeat, and it may be used for other conditions as determined by your doctor.

Acebutolol is a beta-blocker. It works by causing the heart to beat more slowly and regularly.

Do NOT use Acebutolol if:

  • you are allergic to any ingredient in Acebutolol
  • you have a very slow heart rate, active heart failure, heart block, shock caused by serious heart problems, a slow heart rate, or low blood pressure caused by a heart attack
  • you are taking mibefradil or verapamil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Acebutolol :

Some medical conditions may interact with Acebutolol . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, if you become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart failure, other heart problems (eg, slow heart rate, valve disease, ventricular problems), low blood pressure, or blood vessel problems (eg, narrowing of the blood vessels)
  • if you have breathing or lung problems (eg, bronchitis, asthma, chronic obstructive pulmonary disease), diabetes, overactive thyroid, liver or kidney problems, or if you are having a severe allergic reaction

Some MEDICINES MAY INTERACT with Acebutolol . Tell your health care provider if you are taking any other medicines, especially the following:

  • Indomethacin, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or phenylpropanolamine because the effectiveness of Acebutolol may be decreased
  • Disopyramide, flecainide, ketanserin, mibefradil, or reserpine because side effects such as severe low blood pressure or slow heart rate may occur
  • Mefloquinone or verapamil because risk of serious heart problems may be increased
  • Bupivacaine, disopyramide, flecainide, ketanserin, or quinazolines (eg, alfuzosin) because the actions and side effects of these medicines may be increased
  • Clonidine because severe high blood pressure may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acebutolol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Acebutolol :

Use Acebutolol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Acebutolol may be taken with or without food.
  • Using Acebutolol at the same time each day will help you to remember.
  • Continue to use Acebutolol even if you feel well. Do not miss any doses.
  • If you miss a dose of Acebutolol , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acebutolol .

Important safety information:

  • Acebutolol may cause drowsiness, dizziness, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using Acebutolol alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Acebutolol may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
  • Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.
  • Diabetes patients - Acebutolol may mask signs of low blood sugar, such as a rapid heart beat. Other symptoms such as sweating may still occur. Acebutolol may affect blood sugar levels. Your doctor may need to change the dose of diabetes medicine you take. Check blood glucose levels regularly.
  • Do not stop taking Acebutolol without talking to your doctor first. If Acebutolol is suddenly stopped, it may cause angina (chest pain) or heart attack in some patients.
  • Talk to your doctor before taking any nonprescription cold medicines (including nasal sprays) or diet pills.
  • If your doctor has instructed you to check your blood pressure and heart rate regularly, be sure to do so.
  • Before you have medical or dental treatments, emergency care, or surgery, tell your doctor or dentist that you are using Acebutolol .
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Acebutolol during pregnancy. Acebutolol is excreted in breast milk. Do not breast-feed while taking Acebutolol .

Possible side effects of Acebutolol :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness or lightheadedness; frequent urination; gas; headache; indigestion; mild drowsiness; nausea; sleepiness; sleeplessness; unusual tiredness or weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain or tightness; difficulty breathing, especially when lying down; shortness of breath; swelling of ankles.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include difficulty breathing, especially when lying down; fainting; lightheadedness, especially upon standing; seizures (convulsions); shortness of breath; swelling of ankles; very slow heart rate; weakness; wheezing.

Proper storage of Acebutolol :

Store Acebutolol at room temperature (59 to 77 degrees F; 15 to 25 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acebutolol out of the reach of children and away from pets.

General information:

  • If you have any questions about Acebutolol , please talk with your doctor, pharmacist, or other health care provider.
  • Acebutolol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Acebutolol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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