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|Abbokinase Open-Cath |
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Category
DescriptionThrombolytic agents are used to dissolve blood clots that have formed in certain blood vessels. These medicines are usually used when a blood clot seriously lessens the flow of blood to certain parts of the body. Thrombolytic agents are also used to dissolve blood clots that form in tubes that are placed into the body. The tubes allow treatments (such as dialysis or injections into a vein) to be given over a long period of time. These medicines are to be given only by or under the direct supervision of a doctor. These medicines are available in the following dosage forms:
Before Receiving This MedicineIn deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For thrombolytic agents, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to alteplase, anistreplase, streptokinase, or urokinase. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy—Tell your doctor if you are pregnant or if you have recently had a baby. There is a slight chance that use of a thrombolytic agent during the first five months of pregnancy may cause a miscarriage. However, both streptokinase and urokinase have been used in pregnant women and have not been reported to cause this problem. Also, studies in pregnant women (for streptokinase) and studies in animals (for urokinase) have not shown that these medicines cause either miscarriage or harm to the fetus (including birth defects). Studies on birth defects with alteplase and anistreplase have not been done in either pregnant women or animals. Breast-feeding—It is not known whether thrombolytic agents pass into the breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking any of these medicines and who wish to breast-feed should discuss this with their doctor. Children—Studies on these medicines have been done only in adult patients, and there is no specific information comparing the use of thrombolytic agents in children with use in other age groups. However, streptokinase has occasionally been used in children to dissolve blood clots in certain blood vessels. Bleeding may be more likely to occur in children, who are usually more sensitive than adults to the effects of streptokinase. Older adults—The need for treatment with a thrombolytic agent (instead of other kinds of treatment) may be increased in elderly patients with blood clots. However, the chance of bleeding may also be increased. It is especially important that you discuss the use of this medicine with your doctor. Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Before you receive a thrombolytic agent, it is especially important that your doctor know if you are taking any of the following:
Also, tell your doctor if you have had an injection of anistreplase or streptokinase within the past year. If you have, these medicines may not work properly if they are given to you again. Your doctor may decide to use alteplase or urokinase instead. Other medical problems—The presence of other medical problems or recent delivery of a child may affect the use of thrombolytic agents. Make sure you tell your doctor if you have any other medical problems, especially:
Also, tell your doctor if you have recently had any of the following conditions:
If you have recently had a baby, use of these medicines may cause serious bleeding. Proper Use of This MedicineDosing—The dose of these medicines will be different for different patients. The dose you receive will depend on the medicine you receive and will be based on the condition for which you are receiving the medicine. In some cases, the dose will also depend on your body weight. Precautions While Using This MedicineThrombolytic agents can cause bleeding that usually is not serious. However, serious bleeding may occur in some people. To help prevent serious bleeding, carefully follow any instructions given by your health care professional. Also, move around as little as possible, and do not get out of bed on your own, unless your health care professional tells you it is all right to do so . Side Effects of This MedicineAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Tell your health care professional immediately if any of the following side effects occur : More common Bleeding or oozing from cuts, gums, wounds, or around the place of injection; fever; low blood pressure Less common or rare Agitation; bloating; blue or purple toes; blurred vision; bruising; changes in facial skin color; chest pain or discomfort; chills; coma; confusion; darkened urine; decreased urine output; depression; dizziness; double vision; fast or irregular breathing; flushing or redness of skin; gangrenous fingers or toes; headache (mild or severe); hostility; indigestion; irritability; lethargy; loss of appetite; muscle cramps or spasms; muscle pain or stiffness; muscle twitching; nausea; nervousness; numbness or tingling in face, arms, legs; pain in side or abdomen, possibly radiating to the back; pain in toes; pain or discomfort in arms, jaw, back or neck; pounding in the ears; purplish red, net-like, blotchy spots on skin; rapid weight gain; seizures; shortness of breath, troubled breathing, tightness in chest, and/or wheezing; skin rash, hives, or itching; slow or fast heartbeat; stupor; sweating; swelling of eyes, face, lips, or tongue; swelling of hands or ankles; trouble in speaking or walking; unusual tiredness or weakness; vomiting; weakness in arms or legs; yellow eyes or skin Frequency not determined Bluish color of fingernails, lips, skin, palms, or nail beds; cough; difficulty breathing; drowsiness; faintness or lightheadedness when getting up from a lying or sitting position suddenly; fatigue; noisy breathing; welts Symptoms of bleeding inside the body Abdominal or stomach pain or swelling; back pain or backaches; blood in urine; bloody or black, tarry stools; constipation; coughing up blood; dizziness; headaches (sudden, severe, or continuing); joint pain, stiffness, or swelling; muscle pain or stiffness (severe or continuing); nosebleeds; unexpected or unusually heavy bleeding from vagina; vomiting of blood or material that looks like coffee grounds Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Additional InformationOnce a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, alteplase may be used in certain patients with the following condition:
Other than the above information, there is no additional information relating to proper use, precautions, or side effects for this use. Revised: 12/17/2003 The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Where can I get more information about Abbokinase Open-Cath ? 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