Zymine

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Zymine, |Zymine

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Zymine

Generic Name: triprolidine (trye PROE li deen)
Brand Names: Zymine

What is triprolidine?

Triprolidine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Triprolidine is used to treat symptoms of seasonal allergy, such as sneezing, itching, watery eyes, and runny nose.

Triprolidine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about triprolidine?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain type of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine such as diphenhydramine or chlorpheniramine. Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by triprolidine.

What should I discuss with my health care provider before taking triprolidine?

Do not take this medication if you are allergic to triprolidine or other antihistamines.

Before using triprolidine, tell your doctor if you are allergic to any drugs, or if you have:

  • glaucoma;

  • kidney disease;

  • an enlarged prostate; or

  • problems with urination.

If you have any of these conditions, you may not be able to use triprolidine, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take triprolidine?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Allergy medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Take triprolidine with food to lessen stomach upset.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken an allergy medicine within the past few days.

Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a triprolidine overdose may include feeling restless or nervous, dizziness, drowsiness, dry mouth, seizure (black-out or convulsions), or coma.

What should I avoid while taking triprolidine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Avoid using other medicines that make you sleepy (such as pain medication, sleeping pills, muscle relaxers, and medicine to treat depression or anxiety). They can add to sleepiness caused by an antihistamine.

Avoid drinking alcohol while you are taking this medication. Alcohol can add to drowsiness caused by an antihistamine. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain type of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine such as diphenhydramine or chlorpheniramine.

Triprolidine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
  • feeling light-headed, fainting;

  • fast, pounding, or uneven heartbeat;

  • confusion, hallucinations, unusual thoughts or behavior;

  • severe dizziness, anxiety, restless feeling, or nervousness; or

  • urinating less than usual or not at all.

Keep using the medication and talk with your doctor if you have any of these less serious side effects:

  • blurred vision;

  • dry mouth, stuffy nose;

  • change in appetite;

  • nausea, stomach pain;

  • constipation, diarrhea;

  • dizziness, drowsiness;

  • problems with memory or concentration;

  • ringing in your ears; or

  • restless or excitability (especially in children).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect triprolidine?

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • an antidepressant;

  • a diuretic (water pill);

  • medication to treat irritable bowel syndrome;

  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

  • aspirin or salicylates (such as Disalcid, Doan"s Pills, Dolobid, Salflex, Tricosal, and others); or

  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

If you are using any of these drugs, you may not be able to use triprolidine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect triprolidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has information about triprolidine written for health professionals that you may read.

What does my medication look like?

Triprolidine is available with a prescription under the brand name Zymine. Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.01. Revision Date: 04/12/2007 11:16:41 AM.



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