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|Tricof PD Syrup

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Tricof PD Syrup

Generic Name: Chlorpheniramine/Dihydrocodeine/Phenylephrine Liquid and Syrup (KLOR-fen-IR-a-meen/dye-HYE-droe-KOE-deen/FEN-il-EF-rin)
Brand Name: Examples include Novahistine DH and Pancof PD

Tricof PD Syrup is used for:

Treating symptoms of the common cold, flu, or hay fever, and other upper respiratory allergies such as cough, congestion, runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes. It may also be used for other conditions as determined by your doctor.

Tricof PD Syrup is a narcotic antitussive (cough suppressant), antihistamine, and decongestant combination. The antitussive works by suppressing the cough center in the brain. The antihistamine works by blocking the action of histamine, which reduces the symptoms of an allergic reaction such as itchy, watery eyes and runny nose. The decongestant shrinks swollen nasal passages, which relieves nasal congestion.

Do NOT use Tricof PD Syrup if:

you are allergic to any ingredient in Tricof PD Syrup or any other codeine-related medicine (eg, codeine)
you have diarrhea associated with poisoning, antibiotic use, or a bacterial infection (from eating or drinking contaminated food or water)
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tricof PD Syrup:

Some medical conditions may interact with Tricof PD Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of alcohol or drug abuse, dependence on narcotics, or suicidal thoughts or behaviors
if you have increased pressure in the head, an unusual growth in the brain (eg, tumor), a recent head injury, Parkinson disease, Reye syndrome, the blood disease porphyria, or a blockage of your stomach, bowel, or bladder
if you have a history of epilepsy or seizures, asthma or other breathing problems (eg, sleep apnea), stomach or intestinal problems, chronic constipation, liver problems, glaucoma, an enlarged prostate gland or other prostate problems, difficulty urinating, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, overactive thyroid, seizures, or stroke
if you have recently had abdominal surgery

Some MEDICINES MAY INTERACT with Tricof PD Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturate anesthetics (eg, thiopental), beta-blockers (eg, propranolol), cimetidine, catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, ketorolac, MAOIs (eg, phenelzine), naltrexone, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Tricof PD Syrup"s side effects, including dangerous sleepiness and a decrease in the ability to breathe
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Rifampin or risperidone because they may decrease Tricof PD Syrup"s effectiveness
Bromocriptine or hydantoins (eg, phenytoin) because their actions and the risk of their side effects may be increased by Tricof PD Syrup
Guanadrel, guanethidine, mecamylamine, methyldopa, mexiletine, or reserpine because their effectiveness may be decreased by Tricof PD Syrup
Naltrexone because it may decreases Tricof PD Syrup"s effectiveness and withdrawal symptoms may occur in patients who have become physically dependent on opioids. You must not take naltrexone until you have stopped taking Tricof PD Syrup for 7 to 10 days and after a naloxone challenge test is negative.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tricof PD Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tricof PD Syrup:

Use Tricof PD Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Tricof PD Syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Tricof PD Syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tricof PD Syrup.

Important safety information:

Tricof PD Syrup may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Tricof PD Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tricof PD Syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
If your symptoms do not get better within 7 days or if they get worse, or if you develop a high fever or persistent headache, check with your doctor.
Use Tricof PD Syrup with caution in the ELDERLY; they may be more sensitive to its effects, especially possible breathing problems and drowsiness.
Tricof PD Syrup should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: It is not known if Tricof PD Syrup can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tricof PD Syrup while you are pregnant. Tricof PD Syrup is found in breast milk. If you are or will be breast-feeding while you use Tricof PD Syrup, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Tricof PD Syrup may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Tricof PD Syrup stops working well. Do not take more than prescribed.

When used for longer than a few weeks or at high doses, some people develop a need to continue taking Tricof PD Syrup. This is known as DEPENDENCE or addiction. If you suddenly stop taking Tricof PD Syrup, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Tricof PD Syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; flushing or redness of face.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; coma; confusion; deep sleep or loss of consciousness; difficulty breathing; diminished mental alertness; hallucinations; hot or cold skin; large and unchanging pupils; sedation; seizures; shaking; sleeplessness; slow heartbeat; slowed breathing.

Proper storage of Tricof PD Syrup:

Store Tricof PD Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tricof PD Syrup out of the reach of children and away from pets.

General information:

If you have any questions about Tricof PD Syrup, please talk with your doctor, pharmacist, or other health care provider.
Tricof PD Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tricof PD Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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