Tri-Luma

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Tri-Luma


Generic Name: Fluocinolone/Hydroquinone/Tretinoin (floo-oh-SIN-oh-lone/hye-droe-KWIN-one/TREH-tih-noyn)
Brand Name: Tri-Luma

Tri-Luma is used for:

Short-term treatment of moderate to severe melasma (darkening) of the face. It is used in combination with sun avoidance measures, including sunscreen use. It may also be used for other conditions as determined by your doctor.

Tri-Luma is a combination topical corticosteroid, depigmentation agent, and keratolytic. Exactly how Tri-Luma works to treat melasma is unknown.

Do NOT use Tri-Luma if:

  • you are allergic to any ingredient in Tri-Luma

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tri-Luma :

Some medical conditions may interact with Tri-Luma . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have eczema, an abnormally high white blood cell count, a sunburn, or asthma
  • if you have any kind of skin infection, cuts, scrapes, or lessened blood flow to your skin
  • if you have measles, tuberculosis (TB), chickenpox, or shingles, or you have had a positive TB test or a recent vaccination

Some MEDICINES MAY INTERACT with Tri-Luma . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Corticosteroids (eg, prednisone) because the risk of their side effects may be increased by Tri-Luma
  • Medicines that may increase your risk of sunburn (eg, tetracycline, hydrochlorothiazide). Check with your doctor or pharmacist if you are unsure if any of your medicines may increase your sunburn risk.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tri-Luma may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tri-Luma :

Use Tri-Luma as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Tri-Luma . Talk to your pharmacist if you have questions about this information.
  • Tri-Luma is for external use only.
  • Apply Tri-Luma at least 30 minutes before bedtime.
  • Wash your hands before and after using Tri-Luma .
  • Gently wash your face and neck with a mild cleanser. Use your fingers, not a washcloth, to apply the cleanser. Rinse and pat the skin dry. Apply a thin film of medicine to the areas of melasma including about ½ inch of normal appearing skin surrounding each lesion. Rub lightly until the medicine is evenly distributed.
  • Do not cover or bandage the treated area unless otherwise directed by your doctor.
  • You may apply a moisturizer to the face in the morning after washing.
  • If you miss a dose of Tri-Luma , skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tri-Luma .

Important safety information:

  • Avoid getting Tri-Luma in your eyes, nose, or mouth. If you get Tri-Luma in your eyes, rinse thoroughly with water.
  • Do not use Tri-Luma on open wounds.
  • Tri-Luma may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Tri-Luma . Use a sunscreen (minimum SPF 30) or wear protective clothing if you must be outside for more than a short time.
  • Talk with your doctor before you use any other medicines or products on your skin. Avoid using other topical medication, medicated or abrasive soaps, or other products that have a strong drying effect or a high alcohol content. While you are using Tri-Luma , you may use cosmetics and/or moisturizers.
  • Do not apply Tri-Luma to skin that is sunburned. Wait until the burn is fully healed before using Tri-Luma .
  • Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Talk with your doctor before you receive any vaccine while you are taking Tri-Luma .
  • Hormonal contraceptives (eg, birth control pills) may cause or worsen melasma. If you are using hormonal contraception, talk with your doctor about the use of an alternative form of birth control.
  • Do not use Tri-Luma for any condition other than that for which it was prescribed.
  • Weather extremes, such as windy or cold weather, may irritate your skin more while you are using Tri-Luma .
  • Tri-Luma may cause a gradual blue-black darkening of the skin. Black patients may be at higher risk for this side effect. Contact your doctor immediately if you develop this symptom.
  • Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.
  • Tri-Luma may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Tri-Luma should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Tri-Luma .
  • PREGNANCY and BREAST-FEEDING: It is not known if Tri-Luma may cause harm to the fetus after topical use. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tri-Luma while you are pregnant. It is not known if Tri-Luma is found in breast milk after topical use. If you are or will be breast-feeding while you use Tri-Luma , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tri-Luma :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; numbness or tingling of the skin; redness, peeling, mild burning, irritation, stinging, dryness, itching, or feeling of warmth at the application site; sensitivity to sunlight.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive hair growth; gradual blue-black darkening of the skin; inflamed hair follicles; inflammation around the mouth; loss of skin color; muscle weakness; severe or persistent burning, redness, swelling, blistering, oozing, crusting, or irritation of the skin; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include clumsiness; dizziness; excessive redness, peeling, and discomfort; flushing; headache; stomach pain. Tri-Luma may be harmful if swallowed.

Proper storage of Tri-Luma :

Store Tri-Luma at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat and light. Do not store in the bathroom. Keep Tri-Luma out of the reach of children and away from pets.

General information:

  • If you have any questions about Tri-Luma , please talk with your doctor, pharmacist, or other health care provider.
  • This medicine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tri-Luma . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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