Tigecycline

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|Tigecycline

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Tigecycline


Generic Name: Tigecycline (tye-ge-SYE-kleen)
Brand Name: Tygacil

Tigecycline is used for:

Treating certain bacterial infections.

Tigecycline is an antibiotic. It works by killing sensitive bacteria.

Do NOT use Tigecycline if:

  • you are allergic to any ingredient in Tigecycline

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tigecycline :

Some medical conditions may interact with Tigecycline . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a tetracycline antibiotic (eg, doxycycline)
  • if you have liver problems

Some MEDICINES MAY INTERACT with Tigecycline . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Warfarin because side effects may be increased by Tigecycline
  • Hormonal contraceptives (eg, birth control pills) because effectiveness may be decreased by Tigecycline

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tigecycline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tigecycline :

Use Tigecycline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tigecycline is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Tigecycline at home, carefully follow the injection procedures taught to you by your health care provider.
  • If Tigecycline contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • To clear up your infection completely, continue using Tigecycline for the full course of treatment even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Tigecycline , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tigecycline .

Important safety information:

  • Tigecycline may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tigecycline . Using Tigecycline alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Tigecycline may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Tigecycline . Use a sunscreen or protective clothing if you must be outside for a prolonged period.
  • Tigecycline is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
  • It is important to use Tigecycline for the full course of treatment. Failure to do so may decrease the effectiveness of Tigecycline and increase the risk that the bacteria will no longer be sensitive to Tigecycline and will not be able to be treated by this or certain other antibiotics in the future.
  • Long-term or repeated use of Tigecycline may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
  • If severe diarrhea, stomach pain/cramps, or bloody stools occur, contact your doctor immediately. This could be a symptom of a serious side effect requiring immediate medical attention. Do not treat diarrhea without consulting your doctor.
  • Tigecycline may decrease the effectiveness of your birth control pill. To prevent pregnancy, be sure to use an additional form of birth control (eg, condoms) while using Tigecycline .
  • Tigecycline is not recommended for use in CHILDREN younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed. Tigecycline may also cause permanent discoloration of the teeth if used during tooth development (CHILDREN younger than 8 years of age).
  • PREGNANCY and BREAST-FEEDING: Tigecycline may cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Tigecycline during pregnancy. It is unknown if Tigecycline is excreted in breast milk. If you are or will be breast-feeding while you are using Tigecycline , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Tigecycline :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; increased sweating; nausea; pain, swelling, or redness at the injection site; stomach upset; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; fast or slow heartbeat; fever, chills, or sore throat; severe or persistent diarrhea; stomach pain; unusual vaginal itching or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include severe or persistent nausea or vomiting.

Proper storage of Tigecycline :

Tigecycline is usually handled and stored by a health care provider. If you are using Tigecycline at home, store Tigecycline as directed by your pharmacist or health care provider. Keep Tigecycline out of the reach of children and away from pets.

General information:

  • If you have any questions about Tigecycline , please talk with your doctor, pharmacist, or other health care provider.
  • Tigecycline is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tigecycline . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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