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|Tetanus and Diphtheria Toxoids |
| Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9 Home Tetanus and Diphtheria Toxoids( Adult Strength, Td ) Pronouncation: (TET-ah-nus and diff-THEER-ee-uh toxoids)Class: Toxoid Available as generic only () Mechanism of ActionPharmacologyInduces antibodies against toxins made by Corynebacterium diphtheriae and Clostridium tetani . Indications and UsageAchievement of active immunity against diphtheria and tetanus. Tetanus and diphtheria toxoids (Td) for adult use is preferred agent for immunizing most adults and children after 7 yr. ContraindicationsImmediate hypersensitivity to product, thimerosal, or any product components; during immunosuppression, acute respiratory tract infection (except for emergency booster recall doses). Dosage and AdministrationPrimary Immunizing SeriesAdults and Children 7 yr and older IM A total of 3 doses (0.5 mL each): 1 dose now followed by 1 dose 4 to 8 wk later and then 1 dose 6 to 12 mo after first dose. Booster DosesAdults IM 0.5 mL at 10-yr intervals throughout life to maintain immunity. Drug InteractionsNone well documented. Laboratory Test InteractionsNone well documented. Adverse ReactionsLocalSmall amount of erythema, induration, pain, tenderness, heat, and edema surrounding injection site, persisting for a few days, is not unusual. Nodule may be palpable at injection site for a few weeks. Allow such nodules to recede spontaneously. Sterile abscess and SC atrophy occur rarely. Adverse reactions often associated with multiple prior booster doses may be manifested 2 to more than 12 hr after administration by erythema, boggy edema, pruritus, lymphadenopathy, and induration surrounding point of injection. Pain and tenderness, if present, are usually not primary complaints. SystemicTransient low-grade fever (temperatures over 38°C [100°F]) following Td administration are unusual; chills, malaise, generalized aches and pains, headaches, flushing, generalized urticaria or pruritus, tachycardia, anaphylaxis, hypotension, neurologic complications. People developing significant adverse reactions should not be given Td, even emergency doses, more frequently than every 10 yr. PrecautionsPregnancyCategory C . LactationUndetermined. Anticoagulant therapyAs with all IM injections, give drug with caution to people receiving anticoagulant therapy. SusceptibilityLike all inactivated vaccines, administration of Td to people receiving immunosuppressant drugs, including high-dose corticosteroids or radiation therapy, may result in insufficient response to immunization. They may remain susceptible despite immunization. Patient Information
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