Ryneze 12-Hour Tablets

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Ryneze 12-Hour Tablets


Generic Name: Chlorpheniramine/Methscopolamine 12-Hour Tablets (klor-fen-EER-a-meen/meth-skoe-POL-a-meen)
Brand Name: Ryneze

Ryneze 12-Hour Tablets is used for:

Relieving sneezing, runny nose, and watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Ryneze 12-Hour Tablets is an antihistamine and anticholinergic combination. It works by blocking a substance in the body that causes sneezing, runny nose, and watery eyes. It also dries the nose and chest.

Do NOT use Ryneze 12-Hour Tablets if:

  • you are allergic to any ingredient in Ryneze 12-Hour Tablets
  • you are taking sodium oxybate (GHB) or a monamine oxidase inhibitor (MAOI) (eg, phenelzine)
  • you have severe heart blood vessel disease, severe high blood pressure, narrow-angle glaucoma, severe bleeding, severe irritation or other serious problems with the esophagus (eg, esophageal achalasia), peptic ulcer, a blockage of the stomach or bowel, bowel motility problems, severe bowel inflammation (eg, ulcerative colitis), or muscle problems (eg, myasthenia gravis)
  • you are unable to urinate or you are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ryneze 12-Hour Tablets:

Some medical conditions may interact with Ryneze 12-Hour Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a hernia, high blood pressure, nerve problems, prostate gland problems, blockage of your bladder, irregular heartbeat, congestive heart failure or other heart problems, trouble urinating, sleep apnea, asthma, or glaucoma, or you are at risk of developing glaucoma

Some MEDICINES MAY INTERACT with Ryneze 12-Hour Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticholinergic medicines (eg, benztropine), barbiturates (eg, phenobarbital), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Ryneze 12-Hour Tablets"s side effects
  • MAOIs (eg, phenelzine) or sodium oxybate (GHB) because the risk of serious side effects, such as high blood pressure or severe drowsiness, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ryneze 12-Hour Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ryneze 12-Hour Tablets:

Use Ryneze 12-Hour Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Ryneze 12-Hour Tablets by mouth with or without food.
  • Swallow Ryneze 12-Hour Tablets whole. Do not break, crush, or chew before swallowing. Some brands of Ryneze 12-Hour Tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
  • Do not take an antacid or medicine for diarrhea within 1 hour before or 2 hours after you take Ryneze 12-Hour Tablets.
  • If you miss a dose of Ryneze 12-Hour Tablets and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ryneze 12-Hour Tablets.

Important safety information:

  • Ryneze 12-Hour Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Ryneze 12-Hour Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ryneze 12-Hour Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Ryneze 12-Hour Tablets may cause dry mouth. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Ryneze 12-Hour Tablets may reduce sweating. Do not become overheated in hot weather or during exercise or during other activities; heatstroke may occur.
  • Ryneze 12-Hour Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Ryneze 12-Hour Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Ryneze 12-Hour Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Ryneze 12-Hour Tablets.
  • Use Ryneze 12-Hour Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Ryneze 12-Hour Tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Ryneze 12-Hour Tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ryneze 12-Hour Tablets while you are pregnant. Ryneze 12-Hour Tablets is found in breast milk. Do not breast-feed while taking Ryneze 12-Hour Tablets.

Possible side effects of Ryneze 12-Hour Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; change in appetite; constipation; dizziness; drowsiness; dry mouth; fast heartbeat; nausea; nervousness; ringing in the ears; stomach upset or pain; sun sensitivity; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficulty urinating; fainting or feeling faint; fever; flushing; hallucinations; seizures; severe clumsiness; severe drowsiness; shortness of breath; sore throat; unusual bruising or bleeding; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include difficulty breathing; extreme dizziness; extreme drowsiness; fixed/large pupils; hot, dry skin; irregular heartbeat; loss of consciousness; mental or mood changes; persistent vomiting; ringing in the ears; seizures.

Proper storage of Ryneze 12-Hour Tablets:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ryneze 12-Hour Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Ryneze 12-Hour Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Ryneze 12-Hour Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ryneze 12-Hour Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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