Respigam injectable

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Respigam, |Respigam injectable

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Respigam

Generic Name: respiratory syncytial virus immune globulin (RSV IG) (injectable) (RES pir tory SIN sih shull VYE rus ih MUNE GLAW byoo lin)
Brand Names: Respigam

What is RSV IG?

Respiratory syncytial virus immune globulin (RSV IG) is a sterilized solution obtained from pooled human blood. It contains the immunoglobulins (or antibodies) to protect against infection from respiratory syncytial virus (RSV), a virus that can cause serious illness in children. Antibodies are substances in the blood that fight infections.

RSV IG is used to help prevent or reduce the severity of lower respiratory tract (lung) disease caused by respiratory syncytial virus in children who are at increased risk.

RSV IG may also be used for purposes other than those listed here.

What is the most important information I should know about RSV IG?

RSV IG is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although RSV IG is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with the doctor the risks and benefits of using RSV IG.

Treatment with immune globulin products such as RSV IG has been associated with the development of kidney problems, sometimes resulting in kidney failure and/or death. Notify the doctor immediately if symptoms such as decreased urination, sudden weight gain, fluid retention or swelling, or shortness of breath occur. These may be signs of kidney problems. Rare cases of aseptic meningitis syndrome (AMS) have been associated with the use of immune globulin products such as RSV IG. Notify the doctor immediately if symptoms such as severe headache, neck stiffness, drowsiness, fever, eye sensitivity to light, painful eye movements, and nausea or vomiting occur. These may be signs of AMS. Stopping treatment with the immune globulin has resulted in resolution of AMS without any lasting problems.

What should I discuss with my healthcare provider before using RSV IG?

Do not use RSV IG without first talking to your doctor if you have
  • kidney disease;

  • diabetes;

  • IgA deficiency; or

  • had a previous allergic reaction to an immune globulin product.

You may not be able to use RSV IG, or you may require a dosage adjustment or special monitoring during treatment.

RSV IG is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use RSV IG without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether RSV IG passes into breast milk. Do not use RSV IG without first talking to your doctor if you are breast-feeding a baby.

How should I take RSV IG?

RSV IG will be administered by intravenous (into a vein) injection by a healthcare provider in a hospital or clinic setting. If RSV IG is being administered at home, your healthcare provider will give you detailed instructions regarding administration.

RSV IG is usually administered once a month during the RSV season. Your healthcare provider will give you detailed instructions on when the medication should be administered.

Your doctor may want to perform monitoring during treatment with RSV IG to monitor progress and side effects.

Your healthcare provider will store RSV IG as directed by the manufacturer. If RSV IG is being stored at home, your healthcare provider will give you storage instructions.

What happens if I miss a dose?

Contact your healthcare provider if a dose of RSV IG is missed.

What happens if I overdose?

Seek emergency medical attention or contact your healthcare provider if an overdose of RSV IG is suspected.

No information is available regarding an overdose of RSV IG.

What should I avoid while taking RSV IG?

Vaccinations that use live strains of the virus (e.g., measles, mumps, and rubella or MMR) given during and for approximately ten months following treatment with RSV IG may not produce the desired response. Additional doses of the vaccine may be necessary to ensure effectiveness.

RSV IG side effects

RSV IG is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although RSV IG is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with the doctor the risks and benefits of using RSV IG.

Treatment with immune globulin products such as RSV IG has been associated with the development of kidney problems, sometimes resulting in kidney failure and/or death. Notify the doctor immediately if symptoms such as decreased urination, sudden weight gain, fluid retention or swelling, or shortness of breath occur. These may be signs of kidney problems. Rare cases of aseptic meningitis syndrome (AMS) have been associated with the use of immune globulin products such as RSV IG. Notify the doctor immediately if symptoms such as severe headache, neck stiffness, drowsiness, fever, eye sensitivity to light, painful eye movements, and nausea or vomiting occur. These may be signs of AMS. Stopping treatment with the immune globulin has resulted in resolution of AMS without any lasting problems. Notify your doctor immediately if a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to RSV IG is experienced.

Other less serious side effects may also occur. Upon injection of the medication, some patients may experience the following side effects:

  • fever;

  • vomiting;

  • diarrhea; or

  • rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect RSV IG?

Vaccinations that use live strains of the virus (e.g., measles, mumps, and rubella or MMR) given during and for approximately ten months following treatment with RSV IG may not produce the desired response. Additional doses of the vaccine may be necessary to ensure effectiveness.

It is not known whether other medications will interact with RSV IG. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products during treatment with RSV IG.

Where can I get more information?

  • Your pharmacist has additional information about RSV IG written for health professionals that you may read.

What does my medication look like?

RSV IG is available with a prescription under the brand name Respigam. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.01. Revision Date: 9/9/04 2:52:07 PM.



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