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|propylthiouracil Propylthiouracil

propylthiouracil

Generic Name: propylthiouracil (pro pil thye oh YOOR ah sill)
Brand Names:

What is propylthiouracil?

Propylthiouracil prevents the thyroid gland from producing too much thyroid hormone.

Propylthiouracil is used to treat hyperthyroidism (over-active thyroid).

Propylthiouracil may also be used for purposes other than those listed here.

What is the most important information I should know about propylthiouracil?

Rarely, propylthiouracil can affect the blood causing decreased levels of red and white blood cells and platelets. This may cause an increased risk of infection, serious bleeding, anemia, and other problems. Contact your healthcare provider immediately if you experience signs of infection such as fever, sore throat, coughing, or painful or difficult urination (may indicate low white blood cells); such as unusual bleeding or bruising, pinpoint red spots on the skin, nosebleeds, black, bloody, or tarry stools, or blood in urine (may indicate low platelets); or unusual tiredness or weakness (may indicate low red blood cells).

Propylthiouracil can lower the activity of the immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with propylthiouracil. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

What should I discuss with my healthcare provider before taking propylthiouracil?

Before taking propylthiouracil, tell your doctor if you have

• liver problems; or

• a blood disorder.

You may not be able to take propylthiouracil, or you may require a dosage adjustment or special monitoring during treatment.

How should I take propylthiouracil?

Take propylthiouracil exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Propylthiouracil can be taken with or without food.

It is important to take propylthiouracil regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with propylthiouracil to monitor progress and side effects.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Symptoms of a propylthiouracil overdose may include nausea, vomiting, headache, joint pain, fever, itching, rash, numbness or tingling, liver problems, blood problems, and others.

What should I avoid while taking propylthiouracil?

Propylthiouracil can lower the activity of the immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with propylthiouracil. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

Propylthiouracil side effects

Rarely, propylthiouracil can affect the blood causing decreased levels of red and white blood cells and platelets. This may cause an increased risk of infection, serious bleeding, anemia, and other problems. Contact your healthcare provider immediately if you experience signs of infection such as fever, sore throat, coughing, or painful or difficult urination (may indicate low white blood cells); such as unusual bleeding or bruising, pinpoint red spots on the skin, nosebleeds, black, bloody, or tarry stools, or blood in urine (may indicate low platelets); or unusual tiredness or weakness (may indicate low red blood cells).

Other less serious side effects may be more likely to occur. Continue to take propylthiouracil, and contact your doctor if you experience any of the following side effects:

• headache;

• nausea or vomiting;

• skin rash or itching; or

• muscle aches or pains.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect propylthiouracil?

Before taking propylthiouracil, tell your doctor if you are taking any of the following medicines:

• warfarin (Coumadin);

• theophylline (Theo-Dur, Theochron, Elixophyllin, others);

• digoxin (Lanoxin); or

• acebutolol (Sectral), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol XL), penbutolol (Levatol), pindolol (Visken), propranolol (Inderal, InnoPran XL), or timolol (Blocadren).

You may not be able to take propylthiouracil, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with propylthiouracil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals and herbal products.

Where can I get more information?

• Your pharmacist has more information about propylthiouracil written for health professionals that you may read.

What does my medication look like?

Propylthiouracil is available with a prescription as a generic product. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.