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|Primidone Primidone |
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Why should Primidone not be prescribed?You should not take Primidone if you have porphyria (an inherited metabolic disorder) or if you are allergic to phenobarbital. Special warnings about PrimidoneRemember that you must not stop taking Primidone suddenly. It can take several weeks for the full effectiveness of Primidone to be seen. Since Primidone is generally given for long periods of time, your doctor will check your blood count every 6 months. Possible food and drug interactions when taking PrimidoneIf Primidone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Primidone with the following: Avoid alcoholic beverages while you are taking Primidone. Special information if you are pregnant or breastfeedingAlthough the effects of Primidone in pregnancy and nursing infants are not known, recent studies show an increase in birth defects in infants born to epileptic women taking anticonvulsant medications (particularly Dilantin and phenobarbital). Although most pregnant women taking anticonvulsant medication give birth to normal, healthy babies, this possibility may also exist with Primidone. If you are pregnant or plan to become pregnant, inform your doctor immediately. Primidone appears in breast milk and can affect a nursing infant, causing excessive sleepiness and drowsiness. If Primidone is essential to your health, your doctor may advise you to stop breastfeeding. Recommended dosageADULTS For people 8 years of age and older who have not been treated before, the doctor will start Primidone as follows, using either 50-milligram or scored 250-milligram Primidone tablets: Days 1 to 3: 100 to 125 milligrams at bedtime Days 4 to 6: 100 to 125 milligrams 2 times a day Days 7 to 9: 100 to 125 milligrams 3 times a day Day 10 to maintenance: 250 milligrams 3 times a day For most adults and children 8 years of age and over, the usual maintenance dosage is 250 milligrams 3 or 4 times a day. If you need more, your doctor may increase the dose to five or six 250-milligram tablets. You should not take more than 500 milligrams 4 times a day (2000 milligrams or 2 grams). In patients already receiving other anticonvulsants, the usual starting dose of Primidone is 100 to 125 milligrams at bedtime; your doctor will gradually increase this dose to a maintenance level as the other drug is gradually decreased. Your doctor will either find a working level for the combination or withdraw the other medication completely. When Primidone is to be used as a single drug, it will take at least 2 weeks to make the transition from two drugs to one. CHILDREN UNDER AGE 8 Days 1 to 3: 50 milligrams at bedtime Days 4 to 6: 50 milligrams 2 times a day Days 7 to 9: 100 milligrams 2 times a day Day 10 to maintenance: 125 milligrams 3 times a day to 250 milligrams 3 times day The usual maintenance dosage is 125 to 250 milligrams 3 times daily or 10 to 25 milligrams per 2.2 pounds of body weight per day, divided into smaller doses. OverdosageAny medication taken in excess can have serious consequences. If you suspect a Primidone overdose, seek medical attention immediately. Where can I get more information about Primidone Primidone ? 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