Platinol AQ

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Platinol AQ


Generic Name: Cisplatin (sis-PLA-tin)
Brand Name: Platinol AQ

Platinol AQ can cause severe kidney problems or allergic reactions. Hearing loss (more common in children), bleeding problems, a decrease in your body"s ability to fight infection (weakened immune system), or severe nausea and vomiting may also occur. The risk of these problems increases as the dose or total amount of Platinol AQ used over time increases. Notify your doctor immediately if you develop changes in the amount of urine, rash, trouble breathing, swelling of the face, fast heartbeat, dizziness, ringing in the ears or hearing loss, unusual bruising or bleeding, nausea and vomiting, unusual tiredness, or signs of an infection (eg, fever, persistent sore throat).


Platinol AQ is used for:

Treating cancer of the testes, ovaries, or bladder. Platinol AQ may be used alone or in combination with other medications. It may also be used for other conditions as determined by your doctor.

Platinol AQ is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

Do NOT use Platinol AQ if:

  • you are allergic to any ingredient in Platinol AQ or other platinum-containing products
  • you have hearing problems, kidney problems, or a weakened immune system

Contact your doctor or health care provider right away if any of these apply to you.

Before using Platinol AQ :

Some medical conditions may interact with Platinol AQ . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Platinol AQ . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Bleomycin, iodine-containing radiopaque agents, or methotrexate because the risk of side effects may be increased
  • Ondansetron because the effectiveness of Platinol AQ may be decreased
  • Carbamazepine, hydantoins (eg, phenytoin), or valproic acid because effectiveness may be decreased by Platinol AQ

This may not be a complete list of all interactions that may occur. Ask your health care provider if Platinol AQ may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Platinol AQ :

Use Platinol AQ as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Platinol AQ is administered as an injection at your doctor"s office, hospital, or clinic.
  • If Platinol AQ contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Drinking extra fluids while you are taking Platinol AQ is recommended, especially before and for 24 hours after you receive Platinol AQ . Check with your doctor for instructions.
  • If Platinol AQ accidentally spills on your skin, wash it off immediately with soap and water.
  • If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Platinol AQ , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Platinol AQ .

Important safety information:

  • Platinol AQ may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
  • Platinol AQ may lower your body"s ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.
  • Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Platinol AQ . Vaccinations may be less effective.
  • LAB TESTS, including hearing tests, kidney function, and magnesium, sodium, potassium, and calcium blood levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Platinol AQ with caution in the ELDERLY because they may be more sensitive to its effects, especially the effects on the kidneys and blood cells.
  • Platinol AQ is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Platinol AQ has been shown to cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Platinol AQ during pregnancy. Platinol AQ is excreted in breast milk. Do not breast-feed while taking Platinol AQ .

Possible side effects of Platinol AQ :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; loss of appetite; muscle pain; nausea; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blindness; blood in the urine or stools; blurred vision; chest pain; decreased urine volume or frequency; dizziness; hearing problems; inability to distinguish colors; infection (fever, chills, sore throat, cough); joint pain; lightheadedness; loss of balance; loss of motor function; loss of taste; numbness, tingling, or pain of the hands or feet; pain, redness, or swelling at the site of injection; ringing in the ears; seizures; unusual bruising or bleeding; unusual tiredness; wheezing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include dark urine; deafness; decreased urination; nausea; vision impairment; vomiting; yellowing of the eyes or skin.

Proper storage of Platinol AQ :

Store Platinol AQ as directed on the prescription label. Platinol AQ is usually handled and stored by a health care provider. If you are using Platinol AQ at home, store Platinol AQ as directed by your pharmacist or health care provider. Keep Platinol AQ out of the reach of children and away from pets.

General information:

  • If you have any questions about Platinol AQ , please talk with your doctor, pharmacist, or other health care provider.
  • Platinol AQ is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Platinol AQ . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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