Phenobarbital Elixir

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|Phenobarbital Elixir

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Phenobarbital Elixir


Generic Name: Phenobarbital Elixir (fee-noe-BAR-bih-tal)
Brand Name: Generic only. No brands available.

Phenobarbital Elixir is used for:

Treating and preventing seizures, and treating sleep disorders. It may also be used to treat other conditions as determined by your doctor.

Phenobarbital Elixir is a barbiturate. It works by depressing the central nervous system or brain. In low doses, it causes mild sedation. As the dose increases, it can cause sleep and even coma. As it causes the brain to relax, it also decreases seizure activity.

Do NOT use Phenobarbital Elixir if:

  • you are allergic to any ingredient in Phenobarbital Elixir
  • you have a history of the blood disorder porphyria
  • you are taking methoxyflurane, sodium oxybate (GHB), or voriconazole
  • you consume alcohol
  • you have liver problems or lung disease with breathing problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Phenobarbital Elixir:

Some medical conditions may interact with Phenobarbital Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have depression, pain, breathing problems, suicidal tendencies, or are in shock
  • if you have a history of substance abuse or dependence

Some MEDICINES MAY INTERACT with Phenobarbital Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Ethanol , MAO inhibitors (eg, phenelzine), quinine, sodium oxybate (GHB), stiripentol, or valproic acid because side effects such as increased sedation and difficulty breathing may occur
  • Ethanol, methoxyflurane, orsodium oxybate because the actions and side effects of these medicines may be increased
  • Anticoagulants (eg, warfarin), beta-blockers (eg, propranolol), clozapine, corticosteroids (eg, hydrocortisone), cyclosporine, doxorubicin, doxycycline, estrogens (eg, estradiol), imatinib, metronidazole, steroidal contraceptives (eg, birth control pills), theophylline, or voriconazolebecause the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Phenobarbital Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Phenobarbital Elixir:

Use Phenobarbital Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Phenobarbital Elixir may be taken with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Phenobarbital Elixir and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Phenobarbital Elixir.

Important safety information:

  • Phenobarbital Elixir may cause dizziness, drowsiness, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Phenobarbital Elixir. Using Phenobarbital Elixir alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Phenobarbital Elixir. Phenobarbital Elixir will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Use Phenobarbital Elixir with caution in the ELDERLY because they may be more sensitive to its effects.
  • Phenobarbital Elixir is not recommended for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
  • For WOMEN taking birth control pills: Phenobarbital Elixir may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are using Phenobarbital Elixir and for a month after stopping Phenobarbital Elixir.
  • PREGNANCY and BREAST-FEEDING: Phenobarbital Elixir has been shown to cause harm to the human fetus. If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Phenobarbital Elixir during pregnancy. Phenobarbital Elixir is excreted in breast milk. If you are or will be breast-feeding while you are using Phenobarbital Elixir, check with your doctor to discuss the risks to your baby.

Phenobarbital Elixir may be habit-forming and lead to DEPENDENCE if used in high doses or for a long period of time. If you are on long-term or high dosage therapy, you may have WITHDRAWAL symptoms (eg, anxiety, nausea, sleeplessness, body aches) if you suddenly stop taking Phenobarbital Elixir. Do not stop taking Phenobarbital Elixir suddenly or change the dose without asking your pharmacist or doctor. Also, when Phenobarbital Elixir is used in high doses or for a long period of time, it may not work as well and may require higher doses to have the same effect. This is known as TOLERANCE. Talk with your doctor if Phenobarbital Elixir stops working as well. Do not take more than prescribed. Discuss overuse with your doctor or pharmacist.

Possible side effects of Phenobarbital Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Clumsiness; dizziness; drowsiness; excessive daytime drowsiness ("hangover effect"); feeling of a whirling motion; headache; lightheadedness; nausea; tired feeling; vomiting; weak bones.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficulty sleeping; fainting; intense pain; very slow breathing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include cold, clammy skin; change in size of pupil; deep sleep; loss of consciousness; slowed or fast breathing.

Proper storage of Phenobarbital Elixir:

Store Phenobarbital Elixir at room temperature (59 to 86 degrees F; 15 to 30 degrees C) in a tightly closed container, away from heat, moisture, and light. Do not store in the bathroom. Keep Phenobarbital Elixir out of the reach of children and away from pets.

General information:

  • If you have any questions about Phenobarbital Elixir, please talk with your doctor, pharmacist, or other health care provider.
  • Phenobarbital Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Phenobarbital Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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