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Adagen, |pegademase bovine

pegademase bovine

Generic Name: pegademase bovine (peg AD de mace bow vine)
Brand Names: Adagen

What are pegademase bovine?

Pegademase bovine is the enzyme called adenosine deaminase (ADA). Without ADA, certain proteins accumulate that harm white blood cells. White blood cells are important for protecting the body from infection.

Pegademase bovine is used to replenish ADA which allows an increase in white blood cells and decreases the risk of infection in conditions such as severe combined immunodeficiency disease (SCID).

Pegademase bovine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about pegademase bovine?

What should I discuss with my healthcare provider before using a pegademase bovine?

Before using pegademase bovine, tell your doctor if you

• are undergoing radiation or receiving chemotherapy; or

• have a bleeding disorder.

You may not be able to use pegademase bovine or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

How should I use pegademase bovine?

Use pegademase bovine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Pegademase bovine is given by intramuscular (IM) injection. Your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject the medication.

Pegademase bovine is usually administered once every 7 days.

Properly store and discard all syringes and needles.

Your doctor may want you to have regularly scheduled blood tests while using pegademase bovine to monitor effectiveness and possible side effects of the medication.

Do not stop taking pegademase bovine without talking to your doctor. It may take several weeks to 6 months to be fully effective. Stopping pegademase bovine may cause your immune system to become less effective and serious infections may occur.

What happens if I miss a dose?

Contact your doctor as soon as possible if you miss a dose of this medication.

What happens if I overdose?

Symptoms of a pegademase bovine overdose are not known.

What should I avoid while using pegademase bovine?

There are no restrictions regarding foods, beverages, or activities during treatment with pegademase bovine unless otherwise directed by your doctor.

Pegademase bovine side effects

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or

• signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor if you experience:

• headache;

• swelling, redness, or pain at the injection site.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect pegademase bovine?

Before using this medication, tell your doctor if you

• are receiving vidarabine eye ointment (Vira-A).

You may not be able to use the pegademase bovine or you may require a dosage adjustment or special monitoring if you are taking the medication listed above.

Drugs other than those listed here may also interact with pegademase bovine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

• Your pharmacist has additional information about pegademase bovine written for health professionals that you may read.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.