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Eryzole, Pediazole, Sulfimycin, |Pediazole

Pediazole

Generic Name: erythromycin and sulfisoxazole (er ith roe MYE sin and sul FI sox a zol)
Brand Names: Eryzole, Pediazole, Sulfimycin

What is erythromycin and sulfisoxazole?

Erythromycin and sulfisoxazole are antibiotics. They fight bacteria in your body.

Erythromycin and sulfisoxazole is used to treat many different types of bacterial infections.

Erythromycin and sulfisoxazole may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about erythromycin and sulfisoxazole?

What should I discuss with my healthcare provider before taking erythromycin and sulfisoxazole?

Before taking erythromycin and sulfisoxazole, tell your doctor if you have

• kidney disease,

• liver disease,

• a glucose 6-phosphate dehydrogenase deficiency (G6PD deficiency), or

• blood problems.

You may not be able to take erythromycin and sulfisoxazole, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

How should I take erythromycin and sulfisoxazole?

Take erythromycin and sulfisoxazole exactly as directed by your doctor. If you do not understand these instructions, ask your nurse, doctor, or pharmacist to explain them to you.

Erythromycin and sulfisoxazole should be taken at evenly spaced intervals throughout the day and night to keep the amount of medication in your blood high enough to treat the infection.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

If you have only missed one dose, you can take the rest of your scheduled doses for the day at evenly spaced intervals.

What happens if I overdose?

Symptoms of a erythromycin and sulfisoxazole overdose include decreased appetite, nausea, vomiting, diarrhea, dizziness, headache, abdominal discomfort, drowsiness, fever, and unconsciousness.

What should I avoid while taking erythromycin and sulfisoxazole?

Erythromycin and sulfisoxazole side effects

• an allergic reaction (shortness of breath; closing of your throat; hives; swelling of your lips, face, or tongue; rash; or fainting);

• blood in your urine;

• liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).

• ringing in your ears;

• difficulty breathing, sore throat, or chills;

• a rash;

• severe watery diarrhea and abdominal cramps; or

• unusual bleeding or bruising.

Other, less serious side effects may be more likely to occur. Continue to take the erythromycin and sulfisoxazole and talk to your doctor if you experience

• headache, fatigue, or dizziness;

• nausea, vomiting, decreased appetite, or diarrhea;

• vaginal yeast infection;

• increased sensitivity to sunlight;

• weakness; or

• increased sensitivity to the sun.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect erythromycin and sulfisoxazole?

• terfenadine (Seldane, Seldane-D);

• astemizole (Hismanal);

• cisapride (Propulsid); or

• pimozide (Orap).

Erythromycin may interact with these medicines resulting in dangerous or life-threatening irregular heartbeats.

Before taking erythromycin and sulfisoxazole, tell your doctor if you are taking any of the following medicines:

• an oral anticoagulant (blood thinner) such as warfarin (Coumadin);

• digoxin (Lanoxin);

• theophylline (Theo-Dur, Theobid, and others);

• midazolam (Versed) or triazolam (Halcion);

• ergotamine (Ercaf, Cafergot, Ergostat, Ergomar) or dihydroergotamine (D.H.E. 45, Migranal);

• carbamazepine (Tegretol);

• valproic acid (Depakote, Depakene);

• tacrolimus (Prograf);

• cyclosporine (Sandimmune, Neoral);

• lovastatin (Mevacor) or simvastatin (Zocor);

• bromocriptine (Parlodel);

• disopyramide (Norpace);

• cisapride (Propulsid);

• other antibiotics;

• pimozide (Orap);

• an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Glynase, Micronase, Diabeta), chlorpropamide (Diabinese), tolbutamide (Orinase), or tolazamide (Tolinase); or

• phenytoin (Dilantin).

You may not be able to take erythromycin and sulfisoxazole or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with erythromycin and sulfisoxazole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins, minerals, and herbal products .

Where can I get more information?

• Your pharmacist has additional information about erythromycin and sulfisoxazole written for health professionals that you may read.

What does my medication look like?

Erythromycin and sulfisoxazole is available with a prescription generically and under several brand names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.