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SALICYLIC ACID (Topical)

Some commonly used brand names are:

In the U.S.—

Antinea
Buf-Puf Acne Cleansing Bar with Vitamin E
Calicylic Creme
Clearasil Clearstick Maximum Strength Topical Solution
Clearasil Clearstick Regular Strength Topical Solution
Clearasil Double Textured Pads Maximum Strength
Clearasil Double Textured Pads Regular Strength
Clearasil Medicated Deep Cleanser Topical Solution
Clear Away
Clear by Design Medicated Cleansing Pads
Compound W Gel
Compound W Liquid
Duofilm
Duoplant Topical Solution
Freezone
Gordofilm
Hydrisalic
Ionax Astringent Skin Cleanser Topical Solution
Ionil Plus Shampoo
Ionil Shampoo
Keralyt
Keratex Gel
Lactisol
Listerex Golden Scrub Lotion
Listerex Herbal Scrub Lotion
Mediplast
Noxzema Anti-Acne Gel
Noxzema Anti-Acne Pads Maximum Strength
Noxzema Anti-Acne Pads Regular Strength
Occlusal-HP Topical Solution
Occlusal Topical Solution
Off-Ezy Topical Solution Corn & Callus Remover Kit
Off-Ezy Topical Solution Wart Removal Kit
Oxy Clean Medicated Cleanser
Oxy Clean Medicated Pads Maximum Strength
Oxy Clean Medicated Pads Regular Strength
Oxy Clean Medicated Pads Sensitive Skin
Oxy Night Watch Maximum Strength Lotion
Oxy Night Watch Sensitive Skin Lotion
Paplex
Paplex Ultra
Propa pH Medicated Acne Cream Maximum Strength
Propa pH Medicated Cleansing Pads Maximum Strength
Propa pH Medicated Cleansing Pads Sensitive Skin
Propa pH Perfectly Clear Skin Cleanser Topical Solution Normal/Combination Skin
Propa pH Perfectly Clear Skin Cleanser Topical Solution Oily Skin
Propa pH Perfectly Clear Skin Cleanser Topical Solution Sensitive Skin Formula
P&S
Salac
Salacid
Sal-Acid Plaster
Salactic Film Topical Solution
Sal-Clens Plus Shampoo
Sal-Clens Shampoo
Saligel
Salex
Salonil
Sal-Plant Gel Topical Solution
Sebucare
Stri-Dex Dual Textured Pads Maximum Strength
Stri-Dex Dual Textured Pads Regular Strength
Stri-Dex Dual Textured Pads Sensitive Skin
Stri-Dex Maximum Strength Pads
Stri-Dex Regular Strength Pads
Stri-Dex Super Scrub Pads
Trans-Plantar
Trans-Ver-Sal
Verukan-HP Topical Solution
Verukan Topical Solution
Viranol
Viranol Ultra
Wart-Off Topical Solution
X-Seb

In Canada—

Compound W Gel
Compound W Liquid
Cuplex Gel
Occlusal-HP Topical Solution
Occlusal Topical Solution
Oxy Clean Extra Strength Medicated Pads
Oxy Clean Extra Strength Cleanser Topical Solution
Oxy Clean Medicated Soap
Oxy Clean Regular Strength Medicated Cleanser Topical Solution
Oxy Clean Regular Strength Medicated Pads
Oxy Clean Sensitive Skin Cleanser Topical Solution
Oxy Clean Sensitive Skin Pads
Oxy Night Watch Night Time Acne Medication Extra Strength Lotion
Oxy Night Watch Night Time Acne Medication Regular Strength Lotion
Oxy Sensitive Skin Vanishing Formula Lotion
Salac
Tersac Cleansing Gel
Trans-Ver-Sal

Generic name product may be available in the U.S.

Description

Salicylic acid (sal-i-SILL-ik AS-id) is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Some of these preparations are available only with your doctor"s prescription. Others are available without a prescription; however, your doctor may have special instructions on the proper use of salicylic acid for your medical condition.

Salicylic acid is available in the following dosage forms:

Topical
Cream (U.S.)
Gel (U.S. and Canada)
Lotion (U.S. and Canada)
Ointment (U.S.)
Pads (U.S. and Canada)
Plaster (U.S. and Canada)
Shampoo (U.S.)
Soap (U.S. and Canada)
Topical solution (U.S. and Canada)

Before Using This Medicine

If you are using this medicine without a prescription, carefully read and follow any precautions on the label. For salicylic acid, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to salicylic acid. Also tell your health care professional if you are allergic to any other substances, such as preservatives or dyes.

Pregnancy—This medicine may be absorbed through the mother"s skin. Salicylic acid has not been studied in pregnant women. However, studies in animals have shown that salicylic acid causes birth defects when given orally in doses about 6 times the highest dose recommended for topical use in humans. Before using this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant, especially if you will be using salicylic acid on large areas of your body.

Breast-feeding—Salicylic acid may be absorbed through the mother"s skin. However, topical salicylic acid has not been reported to cause problems in nursing babies. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children—Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Older adults—Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of salicylic acid, especially if you are using a 5% or stronger salicylic acid preparation. Make sure you tell your doctor if you have any other medical problems, especially:

Blood vessel disease

Diabetes mellitus (sugar diabetes)—Use of this medicine may cause severe redness or ulceration, especially on the hands or feet

Inflammation, irritation, or infection of the skin—Use of this medicine may cause severe irritation if applied to inflamed, irritated, or infected area of the skin

Influenza (flu) or
Varicella (chicken pox)—This medicine should not be used in children and teenagers with the flu or chicken pox. There is a risk of Reye"s syndrome.

Kidney disease or
Liver disease—Using this medicine for a long time over large areas could result in unwanted effects

Proper Use of This Medicine

It is very important that you use this medicine only as directed . Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.

Keep this medicine away from the eyes and other mucous membranes , such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.

To use the cream, lotion, or ointment form of salicylic acid:

Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:

Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.
Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:

Wipe the pad over the affected areas.
Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:

This medicine comes with patient instructions. Read them carefully before using.
Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation .
Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks . To do so may cause severe irritation.
Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
Cut the plaster to fit the wart, corn, or callus and apply.
For corns and calluses:
- Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
- Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.
For warts:
- Depending on the product, either:
  - Apply plaster and repeat every 48 hours as needed, or
    - Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.
- Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.
If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:

Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:

Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.
If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:

Wet a cotton ball or pad with the topical solution and wipe the affected areas.
Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:

This medicine comes with patient instructions. Read them carefully before using.
This medicine is flammable. Do not use it near heat or open flame or while smoking .
Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation .
Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks . To do so may cause severe irritation.
Avoid breathing in the vapors from the medicine.
Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.
For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.
For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.
If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.

Dosing—The dose of salicylic acid will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of salicylic acid. If your dose is different, do not change it unless your doctor tells you to do so.

For cream dosage form:
- For corns and calluses:
  - Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.
For gel dosage form:
- For acne:
  - Adults and children—Use the 0.5 to 5% gel one time a day.
- For psoriasis:
  - Adults and children—Use the 5% gel one time a day.
- For common warts:
  - Adults and children—Use the 5 to 26% gel one time a day.
For lotion dosage form:
- For acne:
  - Adults and children—Use the 1 to 2% lotion one to three times a day.
- For dandruff and antiseborrhic dermatitis of the scalp:
  - Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.
For ointment dosage form:
- For acne:
  - Adults and children—Use the 3 to 6% ointment as needed.
- For psoriasis and seborrheic dermatitis:
  - Adults and children—Use the 3 to 10% ointment as needed.
- For common warts:
  - Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.
For pads dosage form:
- For acne:
  - Adults and children—Use one to three times a day.
For plaster dosage form:
- For corns, calluses, common warts, or plantar warts:
  - Adults and children—Use one time a day or one time every other day.
For shampoo dosage form:
- For dandruff or seborrheic dermatitis of the scalp:
  - Adults and children—Use on the scalp one or two times a week.
For soap dosage form:
- For acne:
  - Adults and children—Use as needed.
For topical solution dosage form:
- For acne:
  - Adults and children—Use the 0.5 to 2% topical solution one to three times a day.
- For common warts and plantar warts:
  - Adults and children—Use the 5 to 27% topical solution one or two times a day.
- For corns and calluses:
  - Adults and children—Use the 12 to 27% topical solution one or two times a day.

Missed dose—If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage—To store this medicine:

Keep out of the reach of children.
Store away from heat and direct light.
Keep the medicine from freezing.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine , unless otherwise directed by your doctor:

Abrasive soaps or cleansers
Alcohol-containing preparations
Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])
Cosmetics or soaps that dry the skin
Medicated cosmetics
Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.

Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known

Dryness and peeling of skin; flushing; redness of skin; unusually warm skin

Symptoms of salicylic acid poisoning

Confusion; diarrhea; dizziness; fast or deep breathing; headache (severe or continuing); hearing loss; lightheadedness; nausea; rapid breathing; ringing or buzzing in ears (continuing); severe drowsiness; stomach pain; vomiting

Other side effects may occur that usually do not need medical attention. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Skin irritation not present before use of this medicine (mild); stinging

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your health care professional.

Revised: 01/19/2005

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

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