Nilandron

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Nilandron, |Nilandron

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Nilandron

Generic Name: nilutamide (nih LUTE ah mide)
Brand Names: Nilandron

What is nilutamide?

Nilutamide is an antiandrogen. It works in the body to prevent the actions of androgens (male hormones).

Nilutamide is used in the treatment of prostate cancer.

Nilutamide may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about nilutamide?

Call your doctor immediately if you develop yellow skin or eyes, dark urine, itching, persistent appetite loss, pain in the upper right stomach area, unexplained "flu-like" symptoms, difficulty breathing, shortness of breath, cough, chest pain, or fever. Alcohol may cause facial flushing, dizziness, and other symptoms in approximately 5% of patients when used during treatment with nilutamide. Do not drink alcohol if you experience any of these symptoms.

Nilutamide may cause a delay in your ability to see in the dark after being in a lighted area. Use caution when driving at night, when entering into a tunnel, and in other similar situations. Tinted glasses may alleviate this side effect.

What should I discuss with my healthcare provider before taking nilutamide?

Before taking this medication, tell your doctor if you have

  • liver disease or

  • asthma or another lung disease.

You may not be able to take nilutamide, or you may require a lower dose or special monitoring if you have any of the conditions listed above.

Nilutamide is in the FDA pregnancy category C. This means that it is not known whether nilutamide will harm an unborn baby. Nilutamide is not indicated for use by women. Do not take this medication if you are pregnant or are planning a pregnancy. It is not known whether nilutamide passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take nilutamide?

Take nilutamide exactly as directed by your doctor. However, if you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Take each dose with a full glass of water.

Nilutamide can be taken with or without food or milk.

Treatment with nilutamide should be started on the day of or on the day after surgical castration to have maximum benefits.

Try to take your dose of nilutamide at the same time every day.

Do not stop taking this medication without first talking to your doctor. Store nilutamide at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a nilutamide overdose are not known but might include decreased activity, slow breathing, dizziness, watering eyes, decreased appetite, vomiting, and sedation.

What should I avoid while taking nilutamide?

Alcohol may cause facial flushing, dizziness, and other symptoms in approximately 5% of patients when used during treatment with nilutamide. Do not drink alcohol if you experience any of these symptoms.

Nilutamide may cause a delay in your ability to see in the dark after you have been in a lighted area. Use caution when driving at night, when entering a tunnel, and in similar situations. Tinted glasses may alleviate this side effect.

Nilutamide side effects

If you experience any of the following serious side effects, stop taking nilutamide, and seek emergency medical attention or notify your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives),

  • shortness of breath, cough, chest pain, or fever;

  • liver damage (yellow skin or eyes, dark urine, itching, persistent appetite loss, pain in the upper right stomach area, or unexplained flulike symptoms).

Other less serious side effects may be more likely to occur. Continue to take nilutamide and talk to your doctor if you experience

  • hot flashes,

  • dizziness,

  • constipation,

  • nausea or vomiting,

  • skin rash,

  • loss of appetite,

  • decreased libido,

  • impotence, or

  • poor visual adaptation to darkness or other changes in vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect nilutamide?

Before taking this medication, tell your doctor if you are taking any of the following medicines

  • warfarin (Coumadin),

  • phenytoin (Dilantin), or

  • theophylline (Theo-Dur, Theochron, Theolair, others).

You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with nilutamide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

  • Your pharmacist has additional information about nilutamide written for health professionals that you may read.

What does my medication look like?

Nilutamide is available with a prescription under the brand name Nilandron. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Nilandron 50 mg-white, cylindrical tablets

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with other, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.06. Revision Date: 8/31/04 4:40:01 PM.



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