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MetroCream Cream

Generic Name: Metronidazole Cream, Gel, and Lotion (me-troe-NIH-duh-zole)
Brand Name: Examples include MetroCream, MetroGel, and MetroLotion

MetroCream Cream is used for:

Treating redness and inflammation associated with the skin disorder rosacea. It also may be used to treat other conditions as determined by your doctor.

MetroCream Cream is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell and destroying the bacteria.

Do NOT use MetroCream Cream if:

you are allergic to any ingredient in MetroCream Cream
you are taking an ergot alkaloid (eg, ergotamine) or disulfiram
you are taking an HIV protease inhibitor that contains alcohol (eg, ritonavir); check with your pharmacist if you are unsure if the medicine contains alcohol
you drink alcohol

Contact your doctor or health care provider right away if any of these apply to you.

Before using MetroCream Cream:

Some medical conditions may interact with MetroCream Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a central nervous system disease

Some MEDICINES MAY INTERACT with MetroCream Cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital) because the effectiveness of MetroCream Cream may be decreased
Aminoquinolines (eg, chloroquine), anticoagulants (eg, warfarin), busulfan, carbamazepine, cyclosporine, disulfiram, ergot alkaloids (eg, ergotamine), ethanol, fluorouracil, HIV protease inhibitors containing alcohol (eg, ritonavir), imatinib, lithium, macrolide immunosuppressants (eg, tacrolimus), or mitomycin because the actions and side effects of these medicines may be increased
Amphotericin B or oral contraceptives (eg, birth control pills) because their effectiveness may be decreased by MetroCream Cream

This may not be a complete list of all interactions that may occur. Ask your health care provider if MetroCream Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use MetroCream Cream:

Use MetroCream Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Wash and completely dry the affected area.
Apply a thin layer of MetroCream Cream to the affected area. Gently rub the medicine in until it is evenly distributed.
MetroCream Cream works best if taken at the same time each day.
To clear up your infection completely, continue using MetroCream Cream for the full course of treatment even if you feel better in a few days.
If you miss a dose of MetroCream Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use MetroCream Cream.

Important safety information:

MetroCream Cream in for external use only. Avoid getting MetroCream Cream in your eyes or on the inside of your nose or mouth.
Do not drink alcohol while you are using MetroCream Cream and for at least 3 days after the last dose.
If severe diarrhea, stomach cramps/pain, or bloody stools occur, contact your doctor at once. This could be a symptom of a serious side effect that needs immediate medical attention. Do not treat diarrhea without consulting your doctor.
It is important to use MetroCream Cream for the full course of treatment. Failure to do so may decrease the effectiveness of MetroCream Cream and may increase the risk that the bacteria will no longer be sensitive to MetroCream Cream and will not be able to be treated by this or certain other antibiotics in the future.
Long-term or repeated use of MetroCream Cream may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
MetroCream Cream is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
MetroCream Cream may decrease the effectiveness of your birth control pill. To prevent pregnancy, use an additional form of birth control while using MetroCream Cream.
PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using MetroCream Cream during pregnancy. MetroCream Cream is excreted in breast milk. If you are or will be breast-feeding while you are using MetroCream Cream, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of MetroCream Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning; itching; mild dryness; redness; skin irritation; stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; diarrhea; nausea; stomach cramps/pain; tingling or numbness in hands and feet.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. MetroCream Cream may be harmful if swallowed.

Proper storage of MetroCream Cream:

Store MetroCream Cream at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep MetroCream Cream out of the reach of children and away from pets.

General information:

If you have any questions about MetroCream Cream, please talk with your doctor, pharmacist, or other health care provider.
MetroCream Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about MetroCream Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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