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|Metoclopramide Solution

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Metoclopramide Solution

Generic Name: Metoclopramide Injection Solution (meht-oh-KLOE-pra-mide)
Brand Name: Reglan

Metoclopramide Solution is used for:

Treating symptoms associated with a certain digestive problem in diabetic patients (diabetic gastroparesis) and preventing nausea and vomiting following surgery or administration of certain types of cancer chemotherapy. It is also used during certain medical procedures (eg, small bowel intubation, X-ray of the stomach or bowel). It may also be used for other conditions as determined by your doctor.

Metoclopramide Solution is a gastrointestinal stimulant and anti-nauseant. It works by increasing the movement of the stomach and intestines to help move food and acid out of the stomach more quickly. It also works in certain areas in the brain to decrease nausea.

Do NOT use Metoclopramide Solution if:

you are allergic to any ingredient in Metoclopramide Solution
you have seizures (eg, epilepsy); bleeding, blockage, or perforation in your stomach or intestines; or tumors on your adrenal gland (pheochromocytoma)
you are taking cabergoline or pergolide
you are taking medicines, such as phenothiazines (eg, chlorpromazine) that may cause extrapyramidal reactions (abnormal, involuntary muscle movements of the head, neck, or limbs)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Metoclopramide Solution:

Some medical conditions may interact with Metoclopramide Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have depression, asthma, heart failure, high blood pressure, diabetes, Parkinson disease, blood problems (eg, porphyria), kidney problems, or low levels of an enzyme called methemoglobin reductase

Some MEDICINES MAY INTERACT with Metoclopramide Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

Cisapride or droperidol because side effects, such as muscle rigidity, increased heart rate, and altered mental abilities, may occur
Anticholinergic medicine (eg, hyoscyamine), certain antihistamines (eg, diphenhydramine), or narcotic pain medicines (eg, codeine) because they may decrease Metoclopramide Solution"s effectiveness
Acetaminophen, alcohol, levodopa, phenothiazines (eg, chlorpromazine), sedatives (eg, zolpidem), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), succinylcholine), or tetracycline because the risk of their side effects may be increased by Metoclopramide Solution
Monoamine oxidase inhibitors (eg, phenelzine) because the risk of serious side effects (eg, high blood pressure, seizures) may be increased
Cabergoline, digoxin, or pergolide because their effectiveness may be decreased by Metoclopramide Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Metoclopramide Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Metoclopramide Solution:

Use Metoclopramide Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Metoclopramide Solution is usually given as an injection at your doctor"s office, hospital, or clinic. If you will be using Metoclopramide Solution at home, a health care provider will teach you how to use it. Be sure you understand how to use Metoclopramide Solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
Do not use Metoclopramide Solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
If you miss a dose of Metoclopramide Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Metoclopramide Solution.

Important safety information:

Metoclopramide Solution may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Metoclopramide Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Metoclopramide Solution without first checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Diabetes patients - Metoclopramide Solution may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Metoclopramide Solution. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
Lab tests, including liver and kidney function tests, may be performed while you use Metoclopramide Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Metoclopramide Solution should not be used in CHILDREN younger than 15 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Metoclopramide Solution while you are pregnant. Metoclopramide Solution is found in breast milk. If you are or will be breast-feeding while you use Metoclopramide Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Metoclopramide Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; anxiety; absence of menstrual period; breast growth in males; breast milk production; confusion; diarrhea; dizziness; drowsiness; flushing of the face and upper body; frequent urination; headache; hives; impotence; jitteriness; lack of energy; leakage of urine; pain, swelling, or redness at the injection site; rash; restlessness; sleeplessness; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); altered mental abilities, including lack of response to surroundings; depression with thoughts of suicide; fever; fluid retention; giant hives; increased body heat; increased heart rate; involuntary movements of tongue, face, mouth, or jaw (eg, sticking out of the tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes with involuntary movements of the arms and legs; irregular heart rhythm; irregular pulse and blood pressure; mood changes; muscle rigidness; sweating; tightness in the chest; unusual or unexplained vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; confusion; drowsiness; muscle restlessness; unusual movement of eyes, face, or limbs.

Proper storage of Metoclopramide Solution:

Store vials in the original carton at controlled room temperature between 68 and 77 degrees F (20 and 25 degrees C) until ready to use. Do not store for future use. This product is sensitive to light. It may be stored unprotected from light under normal light conditions up to 24 hours after preparing. Keep Metoclopramide Solution out of the reach of children and away from pets.

General information:

If you have any questions about Metoclopramide Solution, please talk with your doctor, pharmacist, or other health care provider.
Metoclopramide Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Metoclopramide Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

Where can I get more information about Metoclopramide Solution ? We recommend to use www.Drugs.com

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