Methsuximide

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|Methsuximide

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Methsuximide


Generic Name: Methsuximide (meth-SUX-i-mide)
Brand Name: Celontin

Methsuximide is used for:

Treating certain types of seizures when other medicines have failed.

Methsuximide is an anticonvulsant. It works by reducing abnormal nerve transmission in the brain, which helps decrease seizures.

Do NOT use Methsuximide if:

  • you are allergic to any ingredient in Methsuximide or to other succinimides (eg, ethosuximide)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methsuximide :

Some medical conditions may interact with Methsuximide . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have the blood disease porphyria, liver or kidney problems, or lupus

Some MEDICINES MAY INTERACT with Methsuximide . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital) or hydantoins (eg, phenytoin) because the side effects of Methsuximide may be increased
  • Lamotrigine because effectiveness may be decreased by Methsuximide

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methsuximide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methsuximide :

Use Methsuximide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Methsuximide may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • If you miss a dose of Methsuximide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methsuximide .

Important safety information:

  • Methsuximide may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Methsuximide . Using Methsuximide alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • LAB TESTS, including complete blood cell counts, may be required to monitor therapy and check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Methsuximide may cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Methsuximide during pregnancy. It is unknown if Methsuximide is excreted in breast milk. If you are or will be breast-feeding while taking Methsuximide , check with your doctor to discuss the risk to your baby.

If you suddenly stop taking Methsuximide , you may experience WITHDRAWAL symptoms, including seizures.

Possible side effects of Methsuximide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Confusion; constipation; diarrhea; dizziness; drowsiness; headache; incoordination; loss of appetite; nausea; sleeplessness; stomach pain; vomiting; weight loss.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre or aggressive behavior; blurred vision or other vision changes; clumsiness; depression; fever, chills, or sore throat; hallucinations; mood or mental changes; red, swollen, or blistered skin; sensitivity to light; suicidal thoughts or behavior.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include coma; nausea; slow breathing; vomiting.

Proper storage of Methsuximide :

Store Methsuximide at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from light, moisture, and excessive heat (104 degrees F [40 degrees C]). Keep Methsuximide out of the reach of children and away from pets.

General information:

  • If you have any questions about Methsuximide , please talk with your doctor, pharmacist, or other health care provider.
  • Methsuximide is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Methsuximide . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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