Meclofenamate

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|Meclofenamate

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Meclofenamate


Generic Name: Meclofenamate (mek-loe-FEN-uh-mate)
Brand Name: Generic only. No brands available.

Meclofenamate is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs have been associated with serious, possibly fatal, heart and blood vessel risks, such as heart attack and stroke. This risk increases with long-term use of NSAIDs or if you have heart problems. NSAIDs should not be used right before or after bypass heart surgery. Additionally, NSAIDs can cause serious, possibly fatal stomach ulcers and bleeding, which can occur without warning signs. The following factors increase the risk of serious stomach problems in patients being treated with NSAIDs: history of stomach bleeding or ulcer disease, long-term use of NSAIDs, smoking, use of alcohol, poor health, older age, or use of certain medicines, such as anticoagulants (eg, warfarin) or corticosteroids (eg, prednisone), while taking an NSAID. To reduce your risk of serious side effects, take Meclofenamate exactly as instructed, at the lowest dose possible, and for the shortest time needed.


Meclofenamate is used for:

Treating rheumatoid arthritis, osteoarthritis, menstrual cramps, and mild to moderate pain. It may also be used for other conditions as determined by your doctor.

Meclofenamate is an NSAID. It works by preventing prostaglandins from being produced by the injured tissue. It may take several days before maximum relief is noticed. NSAIDs relieve symptoms of inflammation but do not alter the course of the underlying disease.

Do NOT use Meclofenamate if:

  • you are allergic to any ingredient in Meclofenamate or similar medicines

Contact your doctor or health care provider right away if any of these apply to you.

Before using Meclofenamate :

Some medical conditions may interact with Meclofenamate . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin or an NSAID (eg, ibuprofen, naproxen, celecoxib)
  • if you have kidney or liver disease, diabetes, stomach problems (eg, bleeding, perforation, ulcers), heart disease, high blood pressure, swelling, blood disorders, bleeding or clotting problems, asthma, growths in the nose (nasal polyps), canker sores, if you consume alcoholic beverages, or if you are dehydrated

Some MEDICINES MAY INTERACT with Meclofenamate . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), cyclosporine, heparin, lithium, methotrexate, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Meclofenamate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Meclofenamate :

Use Meclofenamate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Meclofenamate comes with an additional patient information sheet called a Medication Guide. Read it carefully and reread it each time you get Meclofenamate refilled.
  • Meclofenamate may be taken with food if it upsets your stomach. Taking it with food may not decrease the risk of stomach or bowel problems (such as bleeding or ulcers) that may occur while taking Meclofenamate . Talk with your doctor or pharmacist if you experience persistent stomach upset.
  • Take Meclofenamate with a full glass (8 oz/240 mL) of water as directed by your doctor.
  • Swallow whole. Do not crush, break, or chew before swallowing.
  • Do not lie down for 30 minutes after taking Meclofenamate .
  • If you miss a dose of Meclofenamate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Meclofenamate .

Important safety information:

  • Meclofenamate may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Meclofenamate . Using Meclofenamate alone, with other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. Limit alcoholic beverages.
  • Serious stomach ulcers or bleeding can occur with Meclofenamate . Taking Meclofenamate in high doses, taking it for long periods of time, or drinking alcohol increases the risk of these side effects. Taking Meclofenamate with food will NOT reduce the risk of these effects. If you have severe stomach or back pain; black, tar-like stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling, contact your doctor or emergency room immediately.
  • Avoid taking aspirin while taking Meclofenamate unless advised to do so by your health care provider.
  • Meclofenamate may alter certain lab test results. Make sure lab personnel and your doctors know you use Meclofenamate .
  • LAB TESTS, including liver function, kidney function, and complete blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Caution is advised when using Meclofenamate in the ELDERLY because they may be more sensitive to its effects, especially stomach bleeding and kidney effects.
  • Meclofenamate is not recommended for use in CHILDREN younger than 14 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Meclofenamate may cause harm to the fetus. Avoid becoming pregnant while taking Meclofenamate . If you think you may be pregnant, discuss with your doctor the benefits and risks of using Meclofenamate during pregnancy. Meclofenamate is excreted in breast milk. Do not breast-feed while taking Meclofenamate .

Possible side effects of Meclofenamate :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; headache; heartburn; indigestion; nausea; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; itching; tightness in the chest; swelling of the mouth, face, lips, or tongue); black stools; change in the amount of urine; dark urine; easy bruising/bleeding; fast heartbeat; fever; mental/mood changes; persistent sore throat; persistent stomach or abdominal pain; pounding in the chest; ringing in the ears; severe headache; stiff neck; stomach pain; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual tiredness; vision changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; coffee ground-like vomit; difficult or slowed breathing; disorientation; dizziness; extreme drowsiness; extreme tiredness; loss of consciousness; mental confusion; numbness; ringing in the ears; seizures; severe stomach pain; unusually fast or slow heartbeat.

Proper storage of Meclofenamate :

Store Meclofenamate at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Meclofenamate out of the reach of children and away from pets.

General information:

  • If you have any questions about this medicine, please talk with your doctor, pharmacist, or other health care provider.
  • Meclofenamate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Meclofenamate . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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