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|Malarone |
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DescriptionAntiprotozoals ((AN-ti-pro-to-ZO-uls)) are medicines that are used to prevent and treat malaria, a red blood cell infection transmitted by the bite of a mosquito. This medicine is a combination of two medicines, atovaquone (a-TOE-va-kwone) and proguanil (pro-GWAN-il). This medicine is available only with your doctor"s prescription, in the following dosage form:
Before Using This MedicineIn deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For atovaquone and proguanil, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to atovaquone or proguanil hydrochloride. Also tell your health care professional if you are allergic to any other substances, such as preservatives or dyes. Pregnancy—Atovaquone and proguanil combination has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant It is advisable for pregnant women to avoid traveling to areas where there is a chance of getting malaria. Breast-feeding—It is not known if atovaquone passes into human breast milk, but it was found in the milk of rats. Proguanil passes into breast milk, but in small quantities. Be sure you have discussed the risks and benefits of this medicine with your doctor. Children—Studies on this medicine have been done only in patients who weigh more than 25 pounds (11 kilograms [kg]) for the prevention of malaria and more than 11 pounds (5 kg) for the treatment of malaria and there is no specific information comparing use of atovaquone and proguanil combination in patients of lesser weight. Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of atovaquone and proguanil in the elderly with use in other age groups. Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking atovaquone and proguanil, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems—The presence of other medical problems may affect the use of atovaquone and proguanil. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This MedicineBe sure to take this medicine at the same time each day. Take this medicine with food or with a milky drink. This will help your body absorb the maximal amount of medicine. If you vomit within 1 hour of taking this medicine, take the entire dose again as soon as your stomach can tolerate it. If you or your child have trouble swallowing tablets, you may crush and mix this medicine with condensed milk just before taking it or giving it to your child. Dosing—The dose of atovaquone and proguanil will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of atovaquone and proguanil. If your dose is different, do not change it unless your doctor tells you to do so. The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking atovaquone and proguanil.
Missed dose— If you miss a dose of this medicine, take it as soon as possible. Contact your doctor as soon as possible for additional instructions since you may need additional protective measures. Storage—To store this medicine:
Precautions While Using This MedicineMalaria is spread by the bites of certain kinds of infected female mosquitoes. If you are living in, or will be traveling to, an area where there is a chance of getting malaria, the following mosquito-control measures will help to prevent infection:
Contact your doctor right away if you experience cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue, shortness of breath, skin rash, tightness in chest, unusual tiredness or weakness or wheezing. These could be symptoms of an allergic reaction. Atovaquone and proguanil may cause your skin to be more sensitive to sunlight than it is normally. Be sure to wear protective clothing and a hat or apply a product to the skin that prevents sunburn before going outside. Side Effects of This MedicineAlong with its needed effects, a medicine may cause some unwanted effects. Side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Check with your doctor as soon as possible if any of the following side effects occur: Incidence not known Blistering, peeling, loosening of skin; chills; convulsions; difficulty swallowing; fast heartbeat; hives or welts; increased sensitivity of skin to sunlight; itching, redness or other discoloration of skin; joint or muscle pain; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; loss of bladder control; muscle spasm or jerking of all extremities; puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue; rash; red, irritated eyes; red skin lesions, often with a purple center; seeing, hearing, or feeling things that are not there; severe mental changes; severe sunburn; shortness of breath; skin rash; sores, ulcers or white spots in mouth or on lips; sudden loss of consciousness; tightness in chest; unusual tiredness or weakness; wheezing However, check with your health care professional if any of the following side effects continue or are bothersome : More common Abdominal pain; back pain; coughing; diarrhea; dreams; fever; headache; itching skin ; lack of or loss of strength; nausea; muscle pain; sore throat; sores in mouth; sneezing; vomiting Less common Acid or sour stomach; belching; blurred or loss of vision; disturbed color perception; dizziness; double vision; flu like symptoms; halos around lights; heartburn; indigestion; loss of appetite; night blindness; overbright appearance of lights; sleeplessness; stomach discomfort, upset or pain; trouble sleeping; tunnel vision; unable to sleep; weight loss Rare Discouragement; fear; feeling sad or empty; irritability; lack of appetite; loss of interest or pleasure; nervousness; trouble concentrating Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Developed: 11/03/2000 The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Where can I get more information about Malarone ? We recommend to use www.Drugs.com Typical mistypes for Malarone nalarone, kalarone, jalarone, mzlarone, mslarone, mwlarone, mqlarone, makarone, maparone, maoarone, malzrone, malsrone, malwrone, malqrone, malaeone, maladone, malafone, malatone, mala5one, mala4one, malarine, malarkne, malarlne, malarpne, malar0ne, malar9ne, malarobe, malarome, malaroje, malarohe, malaronw, malarons, malarond, malaronr, malaron4, malaron3, alarone, mlarone, maarone, malrone, malaone, malarne, malaroe, malaron, amlarone, mlaarone, maalrone, malraone, malaorne, malarnoe, malaroen, mmalarone, maalarone, mallarone, malaarone, malarrone, malaroone, malaronne, malaronee, etc.
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