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|Ipecac Syrup |
Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9 Home Ipecac SyrupPronouncation: (IPP-uh-kak)Class: Antidote Trade Names: Mechanism of ActionPharmacologyProduces vomiting by local irritant effect and stimulation of chemoreceptor trigger zone. PharmacokineticsEliminationEliminated very slowly. May be detected up to 60 days in urine. PeakWithin 20 to 30 min. Duration20 to 25 min. Indications and UsageTreatment of drug overdose and certain poisonings. ContraindicationsDo not use in semiconscious, unconscious, pregnant, or lactating persons; do not use if strychnine, corrosives (eg, alkalis, strong acids), or petroleum distillates have been ingested. Dosage and AdministrationAdultsPO 15 to 30 mL followed by 3 to 4 glasses of water. May repeat dose within 20 min if vomiting does not occur. Children younger than 1 yrPO 5 to 10 mL followed by 1/ 2 glass of water. Children 1 to 12 yrPO 15 mL followed by 1 to 2 glasses of water. General Advice
Drug InteractionsActivated charcoalWill absorb ipecac syrup. Give activated charcoal only after ipecac syrup has produced vomiting. Milk or carbonated beveragesDo not administer with ipecac syrup. Laboratory Test InteractionsNone well documented. Adverse ReactionsCardiovascularHeart conduction disturbances; atrial fibrillation; fatal myocarditis. CNSDepression. GIDiarrhea. PrecautionsPregnancyCategory C . LactationUndetermined. AbuseSevere cardiomyopathies and death may occur in bulimic and anorexic persons abusing ipecac syrup. Syrup/Fluid extractDo not confuse ipecac syrup with ipecac fluid extract, which is 14 times stronger and has caused some deaths. OverdosageSymptomsCardiac conduction disturbances, bradycardia, atrial fibrillation, hypotension, fatal myocarditis. Patient Information
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