Hydrocortisone Solution

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Hydrocortisone Solution


Generic Name: Hydrocortisone Injection Solution (hye-droe-KOR-ti-sone)
Brand Name: Solu-Cortef

Hydrocortisone Solution is used for:

Treating certain conditions associated with decreased adrenal gland function. It is also used to treat severe inflammation due to certain conditions, including severe asthma, severe allergies, rheumatoid arthritis, ulcerative colitis, certain blood disorders, lupus, multiple sclerosis, certain cancers (eg, leukemia), and certain eye and skin conditions. It may also be used for other conditions as determined by your doctor.

Hydrocortisone Solution is a corticosteroid. It works by modifying the body"s immune response to various conditions and decreasing inflammation.

Do NOT use Hydrocortisone Solution if:

  • you are allergic to any ingredient in Hydrocortisone Solution
  • you are taking mifepristone
  • the patient is a premature infant
  • you have a systemic fungal infection
  • you are scheduled to have a smallpox vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hydrocortisone Solution:

Some medical conditions may interact with Hydrocortisone Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of bleeding problems, heart problems (eg, congestive heart failure), heart attack, high blood pressure, kidney problems, liver problems, diabetes, seizures, an underactive thyroid, adrenal gland problems, any mental or mood problems, low blood potassium levels, or high blood sodium levels
  • if you have or have recently had a fungal, bacterial, viral, or other type of infection; herpes infection of the eye; chickenpox; measles; or shingles
  • if you have HIV infection or tuberculosis (TB), or if you have ever had a positive TB skin test
  • if you have any stomach problems (eg, ulcers), intestinal problems (eg, blockage, perforation, infection, unexplained diarrhea, diverticulitis, ulcerative colitis), recent intestinal surgery, or inflammation of the esophagus
  • if you have weak bones (eg, osteoporosis) or muscle problems (eg, myasthenia gravis)
  • if you have had any recent vaccinations (eg, smallpox)

Some MEDICINES MAY INTERACT with Hydrocortisone Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), lithium, or rifampin because they may decrease Hydrocortisone Solution"s effectiveness
  • Aprepitant, clarithromycin, cyclosporine, diltiazem, erythromycin, hormonal contraceptives (eg, birth control pills), itraconazole, ketoconazole, or troleandomycin because side effects, such as adrenal gland or nervous system problems (eg, seizures), may occur
  • Aspirin, mifepristone, or ritodrine because their actions and the risk of their side effects may be increased by Hydrocortisone Solution
  • Live vaccines because their effectiveness may be decreased by Hydrocortisone Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrocortisone Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydrocortisone Solution:

Use Hydrocortisone Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hydrocortisone Solution is usually given as an injection at your doctor"s office, hospital, or clinic. If you will be using Hydrocortisone Solution at home, a health care provider will teach you how to use it. Be sure you understand how to use Hydrocortisone Solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Hydrocortisone Solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Hydrocortisone Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Hydrocortisone Solution.

Important safety information:

  • Hydrocortisone Solution may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills within 12 months after stopping Hydrocortisone Solution.
  • If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does. If you do have contact with anyone who has chickenpox or measles, contact your doctor immediately.
  • Tell your doctor or dentist that you take Hydrocortisone Solution before you receive any medical or dental care, emergency care, or surgery.
  • Check with your doctor before having vaccinations while you are using Hydrocortisone Solution.
  • It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to begin taking additional corticosteroids.
  • Diabetes patients - Hydrocortisone Solution may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including adrenal function tests or blood pressure monitoring, may be performed while you use Hydrocortisone Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Hydrocortisone Solution has benzyl alcohol in it. Do not use it in NEWBORNS or INFANTS. It may cause serious and sometimes fatal nervous system problems and other side effects.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Hydrocortisone Solution.
  • Caution is advised when using Hydrocortisone Solution in CHILDREN; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hydrocortisone Solution while you are pregnant. It is not known if Hydrocortisone Solution is found in breast milk. If you are or will be breast-feeding while you use Hydrocortisone Solution, check with your doctor. Discuss any possible risks to your baby.

If you suddenly stop taking Hydrocortisone Solution, you may experience WITHDRAWAL symptoms, including unbalanced hormones (in both men and women).

Possible side effects of Hydrocortisone Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; clumsiness; dizziness; facial flushing; feeling of whirling motion; general body discomfort; headache; increased appetite; increased sweating; nausea; nervousness; pain, swelling, or redness at the injection site; sleeplessness; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in body fat; changes in menstrual periods; changes in skin color; chest pain; easy bruising or bleeding; mental or mood changes (eg, depression); muscle pain, weakness, or wasting; swelling of feet or legs; seizures; severe nausea or vomiting; sudden severe dizziness or headache; symptoms of infection (eg, fever, chills, sore throat); tendon or bone pain; thinning of the skin; unusual skin sensation; unusual weight gain; vision changes or other eye problems; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include dizziness; fainting; fever; loss of appetite; low blood pressure; low blood sugar; muscle pain; nausea.

Proper storage of Hydrocortisone Solution:

Hydrocortisone Solution is usually handled and stored by a health care provider. If you are using Hydrocortisone Solution at home, store Hydrocortisone Solution as directed by your pharmacist or health care provider. Keep Hydrocortisone Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Hydrocortisone Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Hydrocortisone Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Hydrocortisone Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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